Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g/mol | C10H21N3O5 | 25 G
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Azido-PEG5-alcohol is an azide-terminated polyethylene glycol (PEG) linker containing five ethylene glycol units that is used as a click-chemistry reagent and as a linker in bioconjugation workflows. It participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions and is supplied for research use only.
- Azide functional group for click chemistry
- Five-unit PEG spacer adds hydrophilicity and flexibility
- Suitable for antibody-drug conjugate and PROTAC linker synthesis
- Characterized by NMR and LC-MS, purity >97.0%
- Available in multiple package sizes, including 25 G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC NH2-PEG5-C6-Cl hydrochloride | 2241669-16-7 | 98.0% | 1 G
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NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Applicable in cancer and cancer targeted therapy research
- Classified as PROTAC linkers
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Medchemexpress LLC DBCO-S-S-PEG3-biotin | 1430408-09-5 | 96.9% | 869.12 | 25 MG
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DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Used in the synthesis of PROTACs
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 50 MG
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs and has applications in cancer-programmed cell death.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Applications in cancer-programmed cell death
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 1,11-Bis-maleimidotetraethyleneglycol | 86099-06-1 | 98.0% | 250 MG
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BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands
- One ligand for E3 ubiquitin ligase
- Other ligand for target protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 250 MG
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein. These molecules function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC SX-682 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SX-682 is a potent selective and orally bioavailable inhibitor of CXCR1/2 has the potential to treat castration-resistant prostate cancer. purity: 99%
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 | 2010159-56-3 | MFCD31727698 | 99.3% | 619.80 g/mol | C30H45N5O7S | 500 MG
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(S,R,S)-AHPC-PEG3-NH2 is a VHL E3 ligase ligand-linker conjugate terminating in a primary amine. It is supplied as a research-grade powder for use as a building block in PROTAC synthesis and related chemical biology applications.
- VHL-binding motif for targeted protein degradation studies.
- Three-unit PEG linker with terminal amine for facile conjugation.
- High purity suitable for synthetic applications.
- Supplied as a powder convenient for storage and handling.
- Store and handle per the manufacturer's datasheet recommendations.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bromoacetamido-PEG3-C2-Boc | 1807537-33-2 | C15H28BrNO6 | 1 G
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Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that is utilized in the synthesis of PROTACs. PROTACs themselves are small molecules composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Application: used in the synthesis of PROTACs.
- Mechanism: facilitates the degradation of target proteins via the ubiquitin-proteasome system when incorporated into PROTACs.
- Research use: for research purposes only; not intended for sale to patients.
- Form: liquid (density: 1.252 g/cm3), colorless to light yellow.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dbco-peg3-acid | 2754384-59-1 | 98.4% | 508.56 g/mol | C28H32N2O7 | 10 MG
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DBCO-PEG3-acid is a dibenzocyclooctyne (DBCO)-containing PEG linker designed for copper-free click chemistry (strain-promoted alkyne-azide cycloaddition) in bioconjugation and antibody-drug conjugate synthesis. It is a non-cleavable linker supplied as a solid for laboratory use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C₁₆H₃₂O₉S | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC N-(Amino-PEG3)-N-bis(PEG4-Boc) | 2353409-57-9 | 98.0% | C38H76N2O15 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-(Amino-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Applicable in cancer-programmed cell death research
- Connects two different ligands for PROTAC formation
- Targets E3 ubiquitin ligase and protein of interest
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC N-(Azido-PEG3)-N-bis(PEG4-acid) | 2112731-54-9 | 98.0% | C30H58N4O15 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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N-(Azido-PEG3)-N-bis(PEG4-acid) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an Azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions when combined with Alkyne groups. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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eMolecules 100900-07-0 | 5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt | Combi-Blocks, Inc. | MFCD00051474 | 288.300 | C12H13N2NaO3S | 95.000 | [Na+].NCCNc1cccc2c(cccc12)S([O-])(=O)=O | 1g | 603153060
5-(2-Aminoethylamino)-1-naphthalenesulfonic acid sodium salt | Combi-Blocks, Inc. | 100900-07-0 | MFCD00051474 | 288.300 | C12H13N2NaO3S | 95.000 | [Na+].NCCNc1cccc2c(cccc12)S([O-])(=O)=O | 1g | 603153060
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Chemscene ChemScene | 4-(Trimethylsilyl)benzeneboronic acid | 10G | CS-W001042 | 0.98 | 17865-11-1| MFCD00093348 | 194.12
ChemScene | 4-(Trimethylsilyl)benzeneboronic acid | 10G | CS-W001042 | 0.98 | 17865-11-1| MFCD00093348 | 194.12
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