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Filtered Search Results
Medchemexpress LLC 2-Propenamide, N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)- | 890605-54-6 | 98.2% | 283.32 | 100 MG
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Heclin is an inhibitor of HECT E3 ubiquitin ligases, demonstrating inhibitory effects on Smurf2, Nedd4, and WWP1 with IC50 values of 6.8, 6.3, and 6.9 μM, respectively. This compound is utilized in the research of gastric cancer.
- Inhibits cell viability and IGF1 signaling of BGC803 and MKN45 cell lines in vitro.
- Ameliorates epinecidin-1-mediated MyD88 degradation in Raw264.7 cells in vitro.
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eMolecules AA Blocks LLC 2-Oxaspiro[3 3]heptan-6-amine hydrochloride 100mg 796977778 AA01DCW4 0 000 1523618-04-3 MFCD22415297 149 620 C6H12ClNO
AA Blocks LLC 2-Oxaspiro[3 3]heptan-6-amine hydrochloride 100mg 796977778 AA01DCW4 0 000 1523618-04-3 MFCD22415297 149 620 C6H12ClNO
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Medchemexpress LLC 1,4,7-Triazonane | 4730-54-5 | 129.20 | 500 MG
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1,4,7-Triazonane (1,4,7-Triazacyclononane) is an intermediate used in the synthesis of 1,4,7-trifunctionalized derivatives. It is also considered a potential reagent for compleximetric titrations, demonstrating high cation-binding selectivity. It is for research use only.
- Intermediate in the synthesis of 1,4,7-trifunctionalized derivatives
- Potential reagent for compleximetric titrations with high cation-binding selectivity
- Ships at room temperature in continental US
- Store at 4°C, protect from light
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Medchemexpress LLC Act-389949 | 1258417-54-7 | 100.0% | 428.39 g/mol | C20H18F2N6O3 | 25MG
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ACT-389949 is a potent, selective agonist of formyl peptide receptor type 2 (FPR2/ALX) used as a research reagent. Supplied as a powder for in vitro and in vivo studies, the compound has limited solution stability and is typically dissolved fresh; reported properties include an EC50 of about 3 nM for FPR2, molecular formula C20H18F2N6O3, and molecular weight 428.39 g/mol.
- Potent, selective FPR2/ALX agonist with EC50 ≈ 3 nM.
- High reported purity suitable for research applications.
- Provided as a powder for stable storage at -20°C.
- Soluble in DMSO for in vitro assays with reported protocols for in vivo formulations.
- Suitable for pharmacological and mechanistic studies of FPR2 signaling.
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Medchemexpress LLC SIS17 | 2374313-54-7 | 99.4% | 100 MG
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SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor. It inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs. It is intended for research use only.
- Mammalian histone deacetylase 11 (HDAC 11) inhibitor
- Inhibits demyristoylation of serine hydroxymethyltransferase 2
- Does not inhibit other histone deacetylases
- Suitable for research use
- Inhibits HDAC11 with an IC50 value of 0.83 μM
- Increases fatty acylation level of SHMT2 in MCF7 cells
- Exhibits synergistic cytotoxicity in K562 cells when combined with Oxaliplatin
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Medchemexpress LLC Acetic acid, 2-cyano-, 2-[[(3,4-dichlorophenyl)amino]thioxomethyl] hydrazide | 656222-54-7 | 99.8% | 303.17 g/mol | C10H8Cl2N4OS | 10MG
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iKIX1 is a small-molecule antifungal research compound (CAS 656222-54-7) that inhibits the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, resensitizing drug-resistant Candida glabrata to azole antifungals in vitro. It is supplied for research use and is not for human or clinical use.
- Resensitizes azole-resistant Candida glabrata in vitro.
- Inhibits CgGal11A-CgPdr1 interaction to reduce multidrug resistance.
- High purity suitable for research (HPLC purity 99.76%).
- Molecular formula C10H8Cl2N4OS; molecular weight 303.17 g/mol.
- Includes certificate of analysis and safety data sheet for quality and handling information.
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eMolecules Ambeed 2-Oxaspiro[3 3]heptan-6-amine hydrochloride 250mg 525240633 A813225 0 000 1523618-04-3 MFCD22415297 149 620 C6H12ClNO
Ambeed 2-Oxaspiro[3 3]heptan-6-amine hydrochloride 250mg 525240633 A813225 0 000 1523618-04-3 MFCD22415297 149 620 C6H12ClNO
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Medchemexpress LLC Sappanchalcone | 94344-54-4 | 99.5% | C16H14O5 | 1 MG
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Sappanchalcone is a flavonoid isolated from Caesalpinia sappan L. It induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. It reduces MMP with a significant increase in ROS levels in human colon cancer cells and triggers phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells.
- Isolated from Caesalpinia sappan L.
- Induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells.
- Statistically significant effect on HCT116 cells (IC50 = 37.33 μM) and SW480 cells (IC50 = 54.23 μM).
- Reduces MMP with increased ROS levels in human colon cancer cells.
- Triggers phosphorylation of p53, activating caspases and increasing Bax expression in HCT116 cells.
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Medchemexpress LLC N-(2-((4-(1,1-difluoroethyl)oxazol-2-yl)methyl)-2H-1,2,3-triazol-4-yl)-2-methyl-5-(m-tolyl)oxazole-4 | 1258417-54-7 | 100.0% | 428.39 | C20H18F2N6O3 | 100MG
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ACT-389949 is a potent, selective agonist of formyl peptide receptor 2 (FPR2/ALX) used in pharmacological research on inflammatory pathways. It shows an EC50 of 3 nM for FPR2/ALX internalization and is supplied as a high-purity solid with recommended solvent and formulation guidance for in vitro and in vivo studies.
- Potent FPR2/ALX agonist with an EC50 of 3 nM.
- High reported purity (~99.96%).
- Soluble in DMSO; in vivo formulation protocols available.
- Available in multiple pack sizes from 1 mg to 500 mg.
- Molecular formula C20H18F2N6O3; molecular weight 428.39.
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Medchemexpress LLC BR102910 | 2505339-54-6 | MFCD34565708 | 99.8% | 459.30 | C18H14Cl2F2N4O2S | 50 MG
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A selective fibroblast activation protein (FAP) inhibitor for biochemical and cellular research. It exhibits potent FAP inhibition and weaker activity against prolyl oligopeptidase, making it useful for studies of FAP-related biology and metabolic disease models.
- Potent FAP inhibition (IC50 = 2 nM).
- Also inhibits prolyl oligopeptidase (IC50 = 49.0 μM).
- High purity (99.8%).
- Solid form, white to off-white powder.
- Molecular weight 459.30, formula C18H14Cl2F2N4O2S.
- CAS number 2505339-54-6 for unambiguous identification.
- Store solid at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
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Sigma Aldrich Fine Chemicals Biosciences Heptane suitable for HPLC1L
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. Heptane is an environmentally preferable solvent and greener alternative to hexane for chromatographic purification and thus has been enhanced for Safer Solvents and Auxiliaries. Click here for more information.Tools and techniques for solvent selection green solvent selection guides.Heptane (n-Heptane) is a linear hydrocarbon. Its cetane number has been reported to be 56.
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eMolecules 39487-54-2 | AstaTech | 1-((DIMETHYLAMINO)(PHENYL)METHYL)NAPHTHALEN-2-OL | 0.25g | 483309744 | C90615 | 95 | MFCD10000858 | 277.367 | C19H19NO
AstaTech | 3-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXYLIC ACID | 0.25g | 273167013 | 73418 | 95.000 | 89402-28-8 | MFCD11036125 | 209.100 | C7H3F4NO2
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Medchemexpress LLC Salvigenin | 19103-54-9 | MFCD00238678 | 99.9% | 328.32 g·mol⁻¹ | C18H16O6 | 10 MG
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Salvigenin is a natural polyphenolic flavonoid used in preclinical research for its reported neuroprotective, antitumor, cytotoxic, and immunomodulatory activities. It has been shown to inhibit H2O2-induced apoptosis and is used in biochemical and cell-based studies of ROS signaling and apoptosis pathways. Supplied as a high-purity solid and as a 10 mM solution in DMSO for in vitro use.
- High purity (≈99.9%) suitable for research applications.
- Natural polyphenolic flavonoid with neuroprotective and anticancer activities.
- Inhibits H2O2-induced cell apoptosis; useful for ROS and apoptosis studies.
- Available as a solid and as a 10 mM solution in DMSO for convenient dosing.
- Intended for in vitro biochemical and cell-based assays.
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Medchemexpress LLC SNIPER(BRD)-1 | 2095244-54-3 | 99.7% | 1056.73 | 1 MG
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SNIPER(BRD)-1 is a SNIPER degrader of BRD4, cIAP1, and XIAP. It has IC50 values of 6.8 nM, 17 nM, and 49 nM for cIAP1, cIAP2, and XIAP, respectively. It can be used for cancer research.
- SNIPER degrader of BRD4, cIAP1, and XIAP.
- IC50 values: cIAP1: 6.8 nM, cIAP2: 17 nM, XIAP: 49 nM.
- Can be used for cancer research.
- Significantly reduces protein levels of BRD4, cIAP1, and XIAP in LNCaP cells.
- Purity: 99.68%.
- Appearance: solid, off-white to light yellow.
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Medchemexpress LLC SP-96 50 mg
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SP-96 50MG
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