Tetrahydrofuran
Medchemexpress LLC Tabersonine | 4429-63-4 | MFCD28140545 | 98.0% | 10 MG
Tabersonine is a monoterpenoid indole alkaloid used as a research reagent. It has been reported as an NLRP3 inhibitor and is used in studies of inflammation, apoptosis, and neurodegeneration. Supplied as a 10 MG solid, it is intended for laboratory research use only and not for human or clinical applications.
- Monoterpenoid indole alkaloid with reported NLRP3 inhibitory activity.
- Useful for studying inflammation, apoptosis, and neurodegenerative processes.
- Molecular formula C21H24N2O2; molecular weight 336.43 g·mol-1.
- Supplied as a 10 MG solid for laboratory research.
- For research use only, not for human or clinical use.
Medchemexpress LLC 2-methoxyethyl 4-((4-(4-chlorophenoxy)-3,5-difluorophenyl)sulfonyl)-3-(hydroxycarbamoyl)piperaz... | 1224964-36-6 | 98.3% | 548.92 | C21H21ClF2N3O8S | 10 MG
XL-784 is a small-molecule selective matrix metalloproteinase (MMP) inhibitor provided for research use. It exhibits potent activity across multiple MMP isoforms and is applied in studies of extracellular matrix remodeling, tumor invasion, and metastasis.
- Selective inhibition of multiple MMPs with reported IC50s in the subnanomolar to micromolar range (e.g., MMP-13 0.56 nM, MMP-2 0.81 nM).
- Suitable for biochemical and cell-based studies of extracellular matrix and cancer biology.
- High purity (98.3%) for reliable experimental outcomes.
- Provided as a solid and as a DMSO solution for flexible dosing.
- Molecular weight 548.92 g/mol; CAS number 1224964-36-6.
![Medchemexpress LLC 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate | 99.5% | 612.63 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439242-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate | 99.5% | 612.63 | 50 MG
GSK2983559 is an orally active and potent receptor interacting protein 2 (RIP2) kinase inhibitor. It blocks many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.
- Blocks MDP-induced IL-8 in THP-1 cells.
- Inhibits MDP-induced IL-6 in mouse.
Medchemexpress LLC ABD957 | 3007772-60-0 | 98.14% | C27H36F3N7O5S | 100 MG
ABD957 is a potent and selective covalent inhibitor of the ABHD17 family of depalmitoylases, with an IC50 of 0.21 μM for ABHD17B. It can block N-Ras signaling and the growth of NRAS-mutant AML cells.
- Blocks N-Ras signaling
- Blocks the growth of NRAS-mutant AML cells
![Medchemexpress LLC Urea, N-1,2-dithiolan-4-yl-N'-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- | 2966536-18-3 | 99.7% | 376.37 g·mol⁻¹ | C14H11F3N2O3S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000296983.png-250.jpg)
Medchemexpress LLC Urea, N-1,2-dithiolan-4-yl-N'-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- | 2966536-18-3 | 99.7% | 376.37 g·mol⁻¹ | C14H11F3N2O3S2 | 10 MG
Fast-TRFS is a selective, superfast fluorogenic probe for thioredoxin reductase (TrxR) that produces fluorescence upon reduction of its disulfide bond, enabling rapid imaging of TrxR activity in live cells. It is supplied as a solid or as a 10 mM solution in DMSO and is suitable for cellular imaging and rapid detection assays.
- Selective probe for thioredoxin reductase (TrxR).
- Superfast fluorogenic response upon disulfide reduction.
- Suitable for live-cell imaging of TrxR activity.
- Available as 10 mg solid and 10 mM solution in DMSO.
- High purity (99.7%) and molecular weight 376.37 g·mol⁻¹.
Medchemexpress LLC Ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate | 1254944-66-5 | MFCD18782736 | 99.9% | C18H19NO3S2 | 10MG
SR8278 is a small-molecule REV-ERBα antagonist used in research to modulate circadian rhythm and metabolic pathways. It is provided as a solid with high reported purity and characterized physicochemical data for use in both in vitro and in vivo studies.
- High reported purity suitable for research use.
- Soluble in DMSO at high concentration; documented in vivo vehicle protocols available.
- Powder storage stability at typical laboratory temperatures for extended periods.
- Applicable as a tool compound for studies of circadian biology, metabolism, and related disease models.
- Available in small research-scale quantities and ready-to-use DMSO solutions for convenience.
![Medchemexpress LLC Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | ≥95.0% | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234826.png-250.jpg)
Medchemexpress LLC Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | ≥95.0% | 10MG
Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | ≥95.0% | 10MG
Medchemexpress LLC BMS-1001 hydrochloride | 2113650-04-5 | 98.0% | 25 MG
A small-molecule hydrochloride salt developed as an orally active inhibitor of the PD-1/PD-L1 immune checkpoint. Intended for preclinical research applications, it is supplied at research-grade purity with batch-specific documentation.
- Orally active PD-1/PD-L1 inhibitor for immunology research.
- Hydrochloride salt form to improve solubility.
- High purity suitable for preclinical studies (≈98.0%).
- Available in small-scale quantities for screening and assays.
- Supplied with certificate of analysis and batch data.
Medchemexpress LLC Vebicorvir (ABI-H0731) | 2090064-66-5 | 99.7% | 467.44 g·mol^-1 | C19H12F3N3O4S2 | 5 MG
Vebicorvir (ABI-H0731) is a research-grade small-molecule inhibitor of the hepatitis B virus (HBV) core protein. It functions as a core protein allosteric modulator that suppresses formation of covalently closed circular DNA (cccDNA) in cellular infection models. For research use only.
- Inhibits HBV core protein via allosteric modulation.
- Suppresses cccDNA formation in cellular models (reported EC50 1.84-7.3 μM).
- High chemical purity suitable for biochemical and cellular assays.
- Molecular formula C19H12F3N3O4S2; molecular weight 467.44 g·mol^-1.
- Supplied as a solid, soluble in common organic solvents.
- For research use only; not for human or clinical use.
Medchemexpress LLC G5-7 25mg | 939681-36-4 | 25 MG
G5-7 is an orally active, allosteric JAK2 inhibitor used for research applications. It selectively inhibits JAK2-mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3, and has been reported to induce cell cycle arrest, promote apoptosis, and exhibit antiangiogenic effects.
- Allosteric JAK2 inhibitor with oral activity.
- Selective inhibition of JAK2-mediated EGFR and STAT3 phosphorylation.
- Reported to induce cell cycle arrest and apoptosis.
- Exhibits antiangiogenic activity and glioma research relevance.
- Provided as a solid; 25 mg pack available.
- High purity (approximately 99.6%).
Medchemexpress LLC Nusinersen | 1258984-36-9 | 98.9% | 7127.3 g/mol | C234H340N61O128P17S17 | 5 MG
Nusinersen is an antisense oligonucleotide that modulates SMN2 pre-mRNA splicing to increase production of full-length survival motor neuron (SMN) protein. This research-grade material (CAS 1258984-36-9) is supplied as a purified oligonucleotide for laboratory biochemical and cellular studies; typical pack size is 5 mg and reported purity is 98.91%.
- Antisense oligonucleotide for SMN2 splicing modulation.
- High purity (approximately 98.9%) suitable for biochemical assays.
- Supplied as a solid oligonucleotide for in vitro and ex vivo use.
- Applicable to studies of spinal muscular atrophy mechanisms and SMN biology.
- Characterized by defined molecular formula and molecular weight for reproducible experiments.
Medchemexpress LLC Resorcinolnaphthalein | 41307-63-5 | 99.9% | 10 MG
Resorcinolnaphthalein is a small-molecule research reagent that functions as an angiotensin-converting enzyme 2 (ACE2) enhancer. It is supplied as a solid with high reported purity and is intended for laboratory research use only.
- CAS number 41307-63-5.
- Molecular formula C24H14O5.
- Molecular weight 382.36 g/mol.
- Purity 99.9% (reported).
- Appearance solid, light yellow to orange.
- Biological activity ACE2 enhancer; EC50 19.5 μM.
- Storage recommendations: powder -20°C up to 3 years, 4°C up to 2 years; in solvent -80°C up to 2 years, -20°C up to 1 year.
Medchemexpress LLC Nusinersen | 1258984-36-9 | 7127.30 | 10 MG
Nusinersen is an antisense oligonucleotide active molecule that functions by modifying the pre-messenger RNA splicing of the SMN2 gene, promoting the production of full-length SMN protein. It has been shown to improve spinal muscular atrophy, ameliorating motor function and preventing motoneuron Cajal body disassembly in SMA mouse models.
- Functions as an antisense oligonucleotide active molecule
- Modifies pre-messenger RNA splicing of the SMN2 gene
- Promotes production of full-length SMN protein
- Improves spinal muscular atrophy
- Ameliorates motor function in SMA mouse models
- Prevents motoneuron Cajal body disassembly
- Rescues skeletal muscle fiber size and oxidative metabolism
Medchemexpress LLC Melanin probe-2 (compound 5) | 1285446-04-9 | 99.4% | 300.19 | 50 MG
Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor. It is suitable for the synthesis of 18F-Labeled Picolinamide PET probe (HY-136404).
- Non-radioactive bromopicolinamide precursor
- Used for the synthesis of 18F-Labeled Picolinamide PET probe
eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 500g | 480143994
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 500g | 480143994