Tetrahydrofuran
![Medchemexpress LLC N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000245949.png-250.jpg)
Medchemexpress LLC N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide | 140405-36-3 | MFCD00542031 | 99.7% | 312.37 g/mol | C17H20N4O2 | 50 MG
RSVA405 is a small-molecule research compound that potently activates AMP-activated protein kinase (AMPK) and is orally active in vivo. It facilitates CaMKKβ-dependent AMPK activation (EC50 = 1 μM), inhibits mTOR signaling, promotes autophagy and amyloid-β (Aβ) degradation, and shows anti-inflammatory activity via STAT3 inhibition.
- Potent AMPK activator (EC50 = 1 μM).
- Orally active small-molecule research compound.
- Promotes autophagy and increases Aβ degradation.
- Inhibits mTOR signaling and STAT3-mediated inflammation.
- High purity (≈99.7%) light yellow solid.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 25g | 480143991
eMolecules 96-47-9 | 2-Methyltetrahydrofuran | Oakwood Chemicals | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 50g | 480143992
2-Methyltetrahydrofuran | Oakwood Chemicals | 96-47-9 | MFCD00005367 | 86.134 | C5H10O | 99.000 | CC1CCCO1 | 50g | 480143992
![Medchemexpress LLC Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | 99.8% | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232744.png-250.jpg)
Medchemexpress LLC Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | 99.8% | 100MG
Methyl 3-{[(4-methylphenyl)sulfonyl]amino}benzoate | 173436-66-3 | 99.8% | 100MG
Medchemexpress LLC 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 50 MG
CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with a reported IC50 of 0.5 nM. It shows good intestinal permeability in Caco-2 assays and favorable oral pharmacokinetics in mice. The compound is supplied as a solid for research use and includes standard storage recommendations and available solution formulations.
- Potent CSF1R inhibition (IC50 0.5 nM).
- Molecular formula C25H20F3N5O2; molecular weight 479.45 g/mol.
- High purity (98.04%).
- White to off-white solid physical form.
- Stable storage: powder -20°C for up to 3 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple sizes and as a 10 mM solution in DMSO.
Medchemexpress LLC BDP9066 | 2226507-04-4 | 98.18% | 348.44 | 50 MG
BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase (MRCK) inhibitor. It inhibits MRCKβ with an IC50 of 64 nM in SCC12 cells and has Ki values of 0.0136 nM for MRCKα and 0.0233 nM for MRCKβ. This compound demonstrates a therapeutic effect on skin cancer by reducing substrate phosphorylation.
- Potent and selective inhibitor of MRCKα and MRCKβ.
- Exhibits antiproliferative effects, particularly in hematologic cancer cells.
- Inhibits MLC phosphorylation and blocks motility and invasion of SCC12 squamous cell carcinoma.
- Topical application significantly decreases phosphorylated MRCKα S1003 staining and tumor volumes.
Medchemexpress LLC Rhamnocitrin | 569-92-6 | MFCD00006839 | 300.26 | 1 MG
Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons, and is applicable for studying endothelial-related inflammatory diseases and neuroprotection.
- Scavenges DPPH (IC50=28.38 mM).
- Up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE).
- Blocks NFATc3 nuclear translocation and downstream inflammatory factor expression.
- Induces heme oxygenase HO-1 expression and regulates the ERK/p38 MAPK pathway.
- Inhibits antioxidant and pro-inflammatory cytokines (e.g., IL-6, IL-8) and adhesion molecules (e.g., ICAM-1, VCAM-1).
Medchemexpress LLC Decanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- | 31078-36-1 | 5 MG
N-Vanillyldecanamide is a capsaicinoid isolated from the fruits of Capsicum annuum. It significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner. It has a molecular weight of 307.43 and a chemical formula of C18H29NO3. Its appearance is a solid, white to off-white in color. It is for research use only.
- Capsaicinoid isolated from Capsicum annuum
- Significantly reduced radical length of Lactuca sativa seedling
- Molecular weight of 307.43
- Chemical formula of C18H29NO3
- Appears as a white to off-white solid
- For research use only
Medchemexpress LLC AVJ16 | 2775241-92-2 | 99.6% | C28H27N3O4 | 100 MG
AVJ16 is a cancer cell migration inhibitor targeting the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with an affinity (Kd) of 1.4 μM. It interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation, inhibiting proliferation, invasion, and migration of IGF2BP1-expressing lung adenocarcinoma cells. It also suppresses colony formation and spheroid growth, induces apoptosis in certain cell lines, and demonstrates antitumor activity in xenograft mouse models.
- Targets IGF2BP1, a key protein in cancer cell migration.
- Interferes with mRNA binding to regulate gene expression.
- Inhibits proliferation, invasion, and migration of lung adenocarcinoma cells.
- Suppresses colony formation and spheroid growth.
- Induces apoptosis in relevant cell lines.
- Shows antitumor activity in xenograft mouse models.
Medchemexpress LLC Sphondin | 483-66-9 | 1 MG
Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells.
- Inhibits COX-2.
- Attenuates IL-1β-induced COX-2 protein expression and PGE2 release in A549 cells.
Medchemexpress LLC TMX-4100 | 2367619-63-2 | 98.2% | C11H10N4O2S | 100 MG
TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. It demonstrates a high degradation preference for PDE6D with DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. This compound can be utilized for research into multiple myeloma.
- Demonstrates a high degradation preference for PDE6D in MOLT4 cells.
- Exhibits better proteome-wide degradation selectivity in MOLT4 cells.
- Does not hinder the growth of KRAS-dependent cell lines.
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran is an environmentally favorable alternative to tetrahydrofuran (THf) 1 4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications. Many of its benefits include High boiling pointClean organic-water phase separationReduced energy to recover
Medchemexpress LLC Ecliptasaponin D | 206756-04-9 | MFCD30724971 | 99.3% | 634.84 | C36H58O9 | 10 MG
Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba and supplied for research and analytical applications. It is reported to have anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory activities. Identifiers include CAS 206756-04-9 and molecular formula C36H58O9.
- High purity suitable for analytical and screening assays.
- Characterized molecular weight and formula for reproducibility.
- Supplied in small milligram quantities for compound screening and method development.
- Stable when stored at -20°C and protected from light; in solvent store at -80°C for long-term storage.
- Intended for research use only; not for human or clinical use.
Sigma Aldrich Fine Chemicals Biosciences Tetrahydrofuran inhibitor-
Tetrahydrofuran (THf) is widely employed as a solvent. It constitutes the key fragment of various natural products (polyether antibiotics). THf forms a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1 4-diol is formed as an intermediate during the synthesis of THf. Hot THf is useful for the disSOLUTIONon of polyvinylidene chloride (PVDV).
Sigma Aldrich Fine Chemicals Biosciences 2 Methyltetrahydrofuran Bi
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with Safer Solvents and Auxiliaries and Use of Renewable feedstocks. Click here for more information.2-Methyltetrahydrofuran is an environmentally favorable alternative to tetrahydrofuran (THf) 1 4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications. Many of its benefits include High boiling pointClean organic-water phase separationReduced energy to recover