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Filtered Search Results
Medchemexpress LLC Liensinine perchlorate | 2385-63-9 | MFCD09953798 | 99.7% | 711.20 g/mol | C37H42N2O6·xHClO4 | 10 MG
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Liensinine perchlorate is the perchlorate salt of liensinine, an alkaloid from Nelumbo nucifera supplied as a research reagent. It is used in vitro for biological studies and has reported anti-hypertensive and anti-cancer activities, including induction of apoptosis in colorectal cancer cells. Sold for research use only.
- High purity (99.67%).
- Available in small milligram quantities for screening and mechanistic studies.
- Perchlorate salt form improves solubility for biological assays.
- Identified by CAS number 2385-63-9 for unambiguous chemical reference.
- Handle with appropriate laboratory safety precautions; not for clinical use.
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Medchemexpress LLC Benzobicyclon | 156963-66-5 | MFCD09751259 | 98.0% | 446.97 | C22H19ClO4S2 | 10 MG
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Benzobicyclon analytical standard is supplied for research and analytical applications as a reference material. It is a 4-HPPD inhibitor herbicide that hydrolyzes in water to form the active herbicidal species, producing bleaching and death in susceptible plants. The material is provided at high purity for accurate analytical and testing use.
- Intended for research and analytical applications.
- High purity suitable for reference and analytical workflows.
- Hydrolyzes in water to form the active herbicide.
- Effective against grass, sedge, and broadleaf weeds.
- Suitable for analytical quantification and method development.
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Medchemexpress LLC Erk1/2 inhibitor 2 (ASTX-029) | 2095719-92-7 | >98.0% | 584.04 g/mol | C29H31ClFN5O5 | 25MG
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ASTX029 is a dual-mechanism extracellular signal-regulated kinase (ERK) 1/2 inhibitor developed as a clinical candidate. It inhibits ERK catalytic activity and ERK phosphorylation, with reported ERK2 IC50 ≈ 2.7 nM, and has demonstrated antineoplastic activity in preclinical models and early clinical evaluation. Supplied as a crystalline solid for research use, typical vendor-reported purity is ≥98% (CAS 2095719-92-7).
- Potent dual-mechanism ERK inhibitor with low-nanomolar potency.
- Inhibits both catalytic activity and phosphorylation of ERK.
- Demonstrated antineoplastic activity in preclinical and early clinical studies.
- Supplied as a crystalline solid suitable for in vitro and in vivo formulation.
- Typical purity ≥98% by vendor testing.
- CAS number 2095719-92-7 and molecular weight ≈584.04 g/mol.
- For research use only; not for human therapeutic use.
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Medchemexpress LLC 1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethan-1-one | 1693766-04-9 | 99.5% | 323.39 g·mol⁻¹ | C20H21NO3 | 25 MG
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GSK8573 is a small-molecule research reagent used as a structurally related inactive control for acetyl-lysine competitive bromodomain inhibitors. It exhibits measurable binding to BRD9 (Kd ≈ 1.04 μM) and is supplied with characterization data and storage recommendations for reliable use in biochemical and cell-based assays.
- High purity, supporting reproducible experimental results (reported ≈99.5%).
- Validated as an inactive control for bromodomain inhibitor studies.
- Measurable BRD9 binding, useful for target engagement comparisons.
- Available in multiple pack sizes to suit assay throughput needs.
- Detailed solubility and storage guidance for sample preparation and stability.
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Medchemexpress LLC Naz2329 | 2809469-05-2 | 99.0% | 501.56 g·mol⁻¹ | C21H18F3NO4S3 | 50 MG
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NAZ2329 is a small-molecule research inhibitor that allosterically and preferentially inhibits receptor-type protein tyrosine phosphatases PTPRZ and PTPRG. It is supplied as a solid for laboratory research and is characterized by high purity and established solubility in DMSO.
- Allosterically inhibits PTPRZ and PTPRG (reported IC50: PTPRZ 7.5 μM, PTPRG 4.8 μM).
- Cas number 2809469-05-2.
- Purity 99.02%.
- Molecular formula C21H18F3NO4S3.
- Molecular weight 501.56 g·mol⁻¹.
- Appearance solid, white to off-white.
- Soluble in DMSO (~100 mg/mL).
- Pack size 50 mg.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
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Medchemexpress LLC Ralaniten triacetate | 1637573-04-6 | 98.8% | 521.00 g/mol | C27H33ClO8 | 10MG
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Ralaniten triacetate is an orally active prodrug that targets the androgen receptor N-terminal domain (AR-NTD) and is provided for non-clinical research into AR-driven prostate cancer mechanisms. Manufacturer data include analytical and handling information to support experimental use.
- Prodrug of ralaniten that targets the androgen receptor N-terminal domain.
- Orally active in preclinical studies.
- High purity suitable for research applications.
- Molecular weight 521.00 g/mol; formula C27H33ClO8.
- Appearance: liquid, colorless to light yellow.
- Storage conditions provided for pure form and for solutions.
- For research use only; not for human or veterinary use.
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Medchemexpress LLC N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide | 368449-04-1 | 98.6% | 25MG
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N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide | 368449-04-1 | 98.6% | 25MG
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Medchemexpress LLC D-α-tocopherylquinone | 7559-04-8 | MFCD00135657 | 98.9% | 446.71 | C29H50O3 | 10 MG
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- Oxidation product of α-tocopherol with quinone structure.
- Exhibits antioxidant and anticoagulant activity.
- Reduces oxidative damage from oxidized lipids.
- Interacts with glutathione-S-transferase (GST).
- Used in reactive oxygen species (ROS) and lipid peroxidation research.
- Molecular formula C29H50O3; MW 446.71 Da.
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Medchemexpress LLC p-Ethynylphenylalanine hydrochloride | 188640-63-3 | 99.23% | 225.67 | 50 MG
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p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine hydrochloride) is a potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent, selective, reversible, and competitive inhibitor of tryptophan hydroxylase (TPH).
- Click chemistry reagent.
- Contains an Alkyne group for CuAAc reactions.
- Selectively and reversibly inhibits the biosynthesis of serotonin.
- Decreases 5-HT and 5-HIAA levels in the rat midbrain (at 30 mg/kg; i.p.).
- Does not inhibit aromatic amino acid decarboxylase.
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Medchemexpress LLC Spiro[1H,3H-naphtho[1,8-cd]pyran-1,9'-[9H]xanthen]-3-one, 3',6'-dihydroxy- | 41307-63-5 | 99.9% | 25 MG
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Resorcinolnaphthalein is a small-molecule research reagent (C24H14O5) used as an ACE2 enhancer in biochemical assays. It is supplied as a high-purity solid suitable for in vitro research.
- Functions as an ACE2 enhancer with reported EC50 of 19.5 μM.
- High purity as measured by LCMS (99.9%).
- Provided as a light yellow to orange solid; available in solid quantities and as a 10 mM solution in DMSO.
- Molecular weight 382.4 g/mol; formula C24H14O5.
- Intended for research use only and not for human use.
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Medchemexpress LLC Mpt0b392 | 1346169-92-3 | 99.6% | 404.44 g/mol | C19H20N2O6S | 10 MG
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MPT0B392 is a research-grade microtubule-depolymerizing agent for preclinical studies of tubulin dynamics and cancer drug resistance. It is an orally active quinoline derivative that inhibits tubulin polymerization, activates c-Jun N-terminal kinase (JNK), induces mitotic arrest, and promotes apoptosis. Supplied as a solid or as a 10 mM solution in DMSO for in vitro and in vivo research use.
- Novel microtubule-depolymerizing mechanism supporting tubulin studies.
- Induces JNK activation and mitotic arrest for apoptosis research.
- Available as solid or 10 mM solution in DMSO for flexible dosing.
- High listed purity (99.63%) suitable for biochemical assays.
- Documented molecular weight and formula to aid experimental planning.
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Medchemexpress LLC Bifenthrin | 82657-04-3 | MFCD00143694 | 99.8% | 422.87 | C23H22ClF3O2 | 10 MG
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Bifenthrin is a synthetic pyrethroid insecticide supplied as an analytical standard for research and analytical applications. It is intended for use as a reference material in qualitative and quantitative analysis, method development, and instrument calibration for chromatographic and mass spectrometric techniques.
- Analytical standard suitable for HPLC, GC, and MS.
- High purity (99.8% by LCMS).
- Molecular formula C23H22ClF3O2; molecular weight 422.87.
- Off-white to white solid physical form.
- Store under recommended conditions shown on the certificate of analysis.
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Medchemexpress LLC D-serine, N-[[2-[(3-cyanophenyl)methoxy]-4-...]] hydrochloride | 2113650-04-5 | 98.0% | 100 MG
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BMS-1001 hydrochloride is a small-molecule inhibitor of the PD-1/PD-L1 interaction supplied as the hydrochloride salt for research use. It shows potent binding activity and is intended for in vitro studies of immune checkpoint pathways.
- Orally active PD-1/PD-L1 inhibitor with low cellular toxicity.
- IC50 of 2.25 nM in HTRF binding assay.
- Molecular weight 631.11 and formula C35H35ClN2O7.
- High purity (98.0%) suitable for research applications.
- Provided as a hydrochloride salt to aid solubility in assay buffers.
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Medchemexpress LLC G5-7 10mg | 939681-36-4 | 383.39 g/mol | C22H19F2NO3 | 10 MG
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G5-7 is an orally active, allosteric JAK2 inhibitor intended for research use. It selectively inhibits JAK2-mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3, and has been reported to induce cell cycle arrest, apoptosis, and exhibit antiangiogenic effects relevant to glioma studies.
- Allosteric JAK2 inhibitor with selective inhibition of EGFR (Tyr1068) and STAT3 phosphorylation.
- Reported to induce cell cycle arrest and apoptosis in cellular studies.
- Exhibits antiangiogenic activity relevant to glioma research.
- Off-white to light yellow solid powder suitable for research use.
- High purity (99.55%) to support experimental reproducibility.
- Recommended storage: powder at -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
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Medchemexpress LLC SR8278 | 1254944-66-5 | 99.94% | C18H19NO3S2 | 100 MG
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SR8278 is a REV-ERBα antagonist that inhibits its transcriptional repression activity with an EC50 of 0.47 μM.
- Used to regulate metabolism in organisms
- Studies biological rhythm
- Researches Duchenne muscular dystrophy
- Researches Alzheimer's disease
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