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Filtered Search Results
Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.8% | 842.88 | 50 MG
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AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. It exerts antineoplastic activity. Alflutinib is an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exerts antineoplastic activity
- EGFR inhibitor
- Yellow to orange solid
- Store at 4°C, sealed, away from moisture and light
- In solvent: -80°C for 6 months; -20°C for 1 month
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC N-vanillyldecanamide | 31078-36-1 | MFCD01233545 | 99.9% | 307.43 g·mol⁻¹ | C18H29NO3 | 10 MG
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N-Vanillyldecanamide is a capsaicinoid research chemical (CAS 31078-36-1) isolated from the fruits of Capsicum annuum. It has been reported to reduce the radical length of Lactuca sativa seedlings in a dose-dependent manner. The compound is supplied for laboratory research use with supporting documentation for handling and analysis.
- High purity (99.86%) suitable for analytical and biological studies.
- Molecular formula C18H29NO3 and molecular weight 307.43 g·mol⁻¹.
- Supplied in small laboratory quantities, including a 10 mg pack size.
- Available as a solid and as 10 mM solutions in DMSO for convenience.
- Storage: keep at 4°C and protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Typical applications include capsaicinoid activity studies, plant physiology research, and structure-activity investigations.
- Product documentation includes datasheet, COA, and SDS for quality and safety reference.
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Medchemexpress LLC Linzagolix | 935283-04-8 | 99.7% | 508.42 | 50 MG
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Linzagolix is a potent, non-peptide, and orally active GnRH antagonist. It can be used for uterine fibroids, endometriosis, and adenomyosis research. For research use only.
- Potent, non-peptide, and orally active GnRH antagonist
- Used for uterine fibroids, endometriosis, and adenomyosis research
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Medchemexpress LLC Acrylodan | 86636-92-2 | 95.1% | 225.29 g/mol | C15H15NO | 5 MG
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Acrylodan is a thiol-reactive, environment-sensitive fluorescent dye that covalently labels cysteine residues and reports on local dipolarity and conformational dynamics within binding pockets such as Cys34.
- Reacts with thiols to form a covalent fluorescent adduct.
- Sensitive to local dipolarity and protein dynamics.
- Soluble in DMSO at approximately 50 mg/mL; ultrasonic agitation may be required.
- Purity approximately 95.1%; molecular weight 225.29 g/mol.
- Store protected from light; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC CIL62 | 117593-36-9 | 97.0% | 382.45 | 50 MG
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CIL62 is a caspase-3/7-independent cell death inducer that operates via Necrostatin-1 dependent mechanisms. It exhibits antiproliferative activity against human COLO205, IMR32, and K562 cells.
- Caspase-3/7-independent cell death inducer
- Necrostatin-1 dependent mechanism of action
- Antiproliferative activity against COLO205, IMR32, and K562 cells
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eMolecules 109-99-9 | Tetrahydrofuran ACS | Oakwood Chemicals | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
Tetrahydrofuran ACS | Oakwood Chemicals | 109-99-9 | MFCD00005356 | 72.107 | C4H8O | 99.000 | C1CCOC1 | 1l | 480133467
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Medchemexpress LLC Tenuifoliside B | 139726-36-6 | 5 MG
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Tenuifoliside B is a component isolated from Polygalae Radix. It inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. This compound demonstrates potential cognitive improvement and cerebral protective effects, and it has the potential to be an anti-AD lead compound.
- Demonstrates potential cognitive improvement
- Demonstrates cerebral protective effects
- Has the potential to be an anti-AD lead compound
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Medchemexpress LLC Ecliptasaponin D | 206756-04-9 | 5 MG
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Ecliptasaponin D is a triterpenoid glucoside isolated from Eclipta alba (L.) Hassk, which is the aerial part of Eclipta prostrate. Eclipta prostrate is considered a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory properties.
- Triterpenoid glucoside
- Isolated from Eclipta alba (L.) Hassk
- Anti-inflammatory properties
- Hepatoprotective properties
- Antioxidant properties
- Immunomodulatory properties
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Medchemexpress LLC ETZ (C3-CA-DTZ) | 2989379-61-3 | 99.8% | C34H28N6O6 | 100 MG
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ETZ (C3-CA-DTZ) is a promising luciferase substrate, acting as a prosubstrate that can be activated in vivo by non-specific esterase. This activation enhances the brain delivery of luciferin, making it a valuable tool for research applications. It has a molecular weight of 616.62 and a purity of 99.84%.
- Promising luciferase substrate
- Activated in vivo by non-specific esterase
- Enhances brain delivery of luciferin
- For research use only
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Medchemexpress LLC Rhamnocitrin | 569-92-6 | 300.26 | 5 MG
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Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons by regulating miR-185, STIM-1, NFATc3, and ERK/p38 MAPK pathways. It can be used in the study of endothelial-related inflammatory diseases and neuroprotection.
- Functions as an anti-inflammatory and antioxidant agent.
- Targets STIM-1, NFATc3, and MAPK pathways.
- Inhibits oxidative stress and inflammatory responses.
- Useful for studying endothelial-related inflammatory diseases.
- Useful for neuroprotection research.
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Medchemexpress LLC Ganodermanontriol | 106518-63-2 | 472.70 | 5 MG
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Ganodermanontriol is a sterol isolated from Ganoderma lucidum that induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells by expressing HO-1. It also exhibits hepatoprotective activity. It has been shown to inhibit breast cancer cell lines MCF-7 and MDA-MB-231 with IC50 values of 5.8 and 9.7 μM, respectively.
- Induces anti-inflammatory activity in damaged hepatic cells.
- Exhibits hepatoprotective activity.
- Inhibits breast cancer cell lines MCF-7 and MDA-MB-231.
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Medchemexpress LLC Rhamnocitrin | 569-92-6 | MFCD00006839 | 300.26 | 1 MG
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Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3, and MAPK pathways. It selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons, and is applicable for studying endothelial-related inflammatory diseases and neuroprotection.
- Scavenges DPPH (IC50=28.38 mM).
- Up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE).
- Blocks NFATc3 nuclear translocation and downstream inflammatory factor expression.
- Induces heme oxygenase HO-1 expression and regulates the ERK/p38 MAPK pathway.
- Inhibits antioxidant and pro-inflammatory cytokines (e.g., IL-6, IL-8) and adhesion molecules (e.g., ICAM-1, VCAM-1).
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Medchemexpress LLC Decanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- | 31078-36-1 | 5 MG
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N-Vanillyldecanamide is a capsaicinoid isolated from the fruits of Capsicum annuum. It significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner. It has a molecular weight of 307.43 and a chemical formula of C18H29NO3. Its appearance is a solid, white to off-white in color. It is for research use only.
- Capsaicinoid isolated from Capsicum annuum
- Significantly reduced radical length of Lactuca sativa seedling
- Molecular weight of 307.43
- Chemical formula of C18H29NO3
- Appears as a white to off-white solid
- For research use only
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Medchemexpress LLC 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g/mol | C25H20F3N5O2 | 50 MG
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CSF1R-IN-1 is a potent small-molecule inhibitor of the colony stimulating factor 1 receptor (CSF1R) with a reported IC50 of 0.5 nM. It shows good intestinal permeability in Caco-2 assays and favorable oral pharmacokinetics in mice. The compound is supplied as a solid for research use and includes standard storage recommendations and available solution formulations.
- Potent CSF1R inhibition (IC50 0.5 nM).
- Molecular formula C25H20F3N5O2; molecular weight 479.45 g/mol.
- High purity (98.04%).
- White to off-white solid physical form.
- Stable storage: powder -20°C for up to 3 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple sizes and as a 10 mM solution in DMSO.
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Medchemexpress LLC Nelonicline | 1026134-63-3 | 99.8% | 313.42 g/mol | C17H19N3OS | 10 MG
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Nelonicline is an orally active, selective agonist of the α7 nicotinic acetylcholine receptor supplied as a research reagent for preclinical and in vitro studies. It has molecular formula C17H19N3OS and molecular weight 313.42 g/mol. For research use only; not for clinical or diagnostic applications.
- Selective α7 nicotinic acetylcholine receptor agonist suitable for receptor pharmacology studies.
- Orally active small molecule compatible with in vivo and in vitro experiments.
- Available as a 10 MG solid and as a 10 mM solution in DMSO for assay use.
- High-purity research compound appropriate for preclinical studies.
- Supplied for research use only, not intended for therapeutic use.
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