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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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Histrelin acetate is a GnRH analogue and a GnRH Receptor agonist. It works by increasing serum luteinising hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. It is used in the research of prostate cancer and endometriosis.
Stimulates the release of vasopressin (VP) from isolated rat hypothalamo-neurohypophysial explants
Stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system
Rescues circulating LH concentrations in Csfmop/Csfmop mice
Reduces the number of endometrial glands and atrophies the stroma in rabbits
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Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
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Antioxidant agent-4 is a small-molecule antioxidant reported to exhibit antilipid peroxidative activity. It is supplied for research use and is characterized by its chemical identifiers, purity, and storage stability.
Chemical name 7-methoxybenzo[d][1,3]dioxol-5-ol.
Cas number 50901-34-3.
Molecular formula C8H8O4.
Molecular weight 168.15.
Purity 96.0%.
Storage and stability in solvent: -80°C for 6 months, -20°C for 1 month when stored under nitrogen.
Typical package sizes include 10 mg and solution preparations.
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Antioxidant agent-11 is a chemical compound intended for research use only, exhibiting weak anti-cancer and antioxidant activities. It is supplied as a solid, white to off-white compound with a purity of 95.0%.
Purity of 95.0%
Solid appearance
White to off-white color
Soluble in DMSO at 100 mg/mL (272.91 mM), requiring sonication
Store at 4°C, protected from light; in solvent, -80°C for 6 months or -20°C for 1 month, protected from light
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L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide that demonstrates high affinity to LRP1 with a Ki of 45 nM. It exhibits blood-brain barrier (BBB) permeability and plasma stability, making it suitable as a carrier for Central Nervous System (CNS) drug delivery.
High affinity to LRP1
Blood-brain barrier permeability
Plasma stability
Suitable for CNS drug delivery
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Protirelin acetate is a highly conserved neuropeptide that exerts hormonal control of thyroid-stimulating hormone (TSH) levels and neuromodulatory functions. It is intended for research use only.
Highly conserved neuropeptide
Exerts hormonal control of TSH levels
Functions as a neuromodulator
White to off-white solid appearance
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AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor and a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation, induces a dose-dependent cytotoxic response (mean IC50=1 μM), and induces apoptosis by activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).
Potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 of 6 nM.
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Actinine-d9 chloride is a deuterium-labeled form of Actinine chloride. Actinine chloride is an angiopathic substance produced by gut microbiota from dietary carnitine. This compound is suitable for use as a tracer and as an internal standard in quantitative analyses.
Deuterium labeled compound
Suitable for use as a tracer
Can be used as an internal standard for quantitative analysis
Compatible with NMR, GC-MS, or LC-MS analysis methods
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KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. It conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells and covalently links targeted mRNA and fluorescein to form a delivery system with low re-export and less resistance to serum effects.
Cell membrane-penetrating α-helical amphipathic model peptide.
Conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells.
Forms a delivery system for targeted mRNA and fluorescein.
Exhibits low re-export and less susceptibility to serum effects.
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Ergothioneine-d9 is the deuterium labeled Ergothioneine. Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi. Ergothioneine is generally considered an antioxidant.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Vitamin K1 is a naturally occurring vitamin that is essential for various biological processes, including blood coagulation, bone metabolism, and vascular metabolism.
Naturally occurring vitamin
Required for blood coagulation
Required for bone metabolism
Required for vascular metabolism
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Vitamin A (all-trans-Retinol) is an endogenous metabolite. It plays a role in various biological processes and is studied in contexts such as human gut microbiota metabolism, cellular effects on fibroblasts and cancer cell lines, and its metabolism in hepatic microsomes.
Endogenous metabolite
Role in human gut microbiota metabolism
Exhibits cellular effects on fibroblasts and carcinoma cell lines
Metabolism involves hepatic microsomes
Studied in relation to high-fat diets and methionine-choline deficient diets
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