Prenol lipids
Selleck Chemical LLC Betulinic acid S3603-10mg
Betulinic acid (ALS-357 Lupatic acid Betulic acid) a pentacyclic triterpenoid from Syzigium claviflorum is a inhibitor of HIV-1 with EC50 of 1 4 M It s reported that Betulinic acid acts as a new inhibitor of NF- B Phase 1/2
Selleck Chemical LLC Paclitaxel S1150-100mg
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Apexbio Technology LLC nor-NOHA (acetate) 1140844-63-8 5mg
nor-NOHA (acetate) (CAS 1140844-63-8) is a potent reversible inhibitor of rat liver arginase (Ki 0 5 M) By competitively inhibiting arginase nor-NOHA modulates the cellular balance between the L-arginine-dependent pathways of nitric oxide synthase (NOS) and arginase affecting nitric oxide production and urea cycle metabolism In vitro studies have shown that nor-NOHA suppresses proliferation migration and invasion of HepG2 hepatocellular carcinoma cells induces apoptosis and alters expression of Arg1 MMP-2 P53 and ECD In vivo nor-NOHA improves endothelial function in rat models of inflammation by enhancing NOS activity increasing EDHF and reducing superoxide anion production This compound is widely used to investigate arginase-related mechanisms in cellular and vascular biology
Apexbio Technology LLC Vitamin C(Synonyms: Ascorbic Acid, L-Ascorbic Acid, Ascorbate, L-(+)-Ascorbic Acid), 10mM (in 1mL DMSO), CAS: 50-81-7.
Vitamin C (CAS 50-81-7) is a water-soluble vitamin studied extensively in biomedical contexts for its potential anticancer and antiviral activities Mechanistically vitamin C exerts antiproliferative effects on tumor cells and promotes apoptosis as demonstrated in murine colon cancer (CT26) cells At concentrations of 100-200 g/ml vitamin C inhibited proliferation significantly higher levels (200-1000 g/ml) induced apoptosis dose-dependently In vivo studies showed vitamin C treatment reduced tumor volume markedly in CT26 and 4T1 tumor-bearing BALB/c mouse models These findings highlight vitamin C s utility in cancer research as a therapeutic adjunct and investigational agent
Abcam Chrysin, Antio x idant flavonoid, 1G
MW 254.24 Da, Purity >99%. Antioxidant flavonoid. Anti-inflammatory and antioxidant properties, also able to induce apoptosis. Potent inhibitor of hypoxia-inducible factor 1α (HIF-1α).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Trolo x , Antio x idant vitamin E derivative, 500MG
MW 250.29 g/mol, Purity >98%. Antioxidant vitamin E derivative. Exhibits lipid peroxidizing, DPPH° scavenging and HO° scavenging activity. Regularly used as an antioxidant standard. Cell-permeable and water soluble.
The product is subject to the following: Abcam Restricted Use Statement