Benzenoids
Medchemexpress LLC PD-L1-IN-1 | 2767424-13-3 | 377.44 | 50 MG
PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC50 of 115 nM. It strongly binds to the PD-L1 protein, enhancing the antitumor immune activity of peripheral blood mononuclear cells in co-culture with PD-L1 expressing cancer cells. It increases IFN-γ release and induces apoptosis.
- Potent PD-L1 inhibitor.
- Enhances antitumor immune activity.
- Induces apoptosis.
- Exhibits low cytotoxicity in healthy cells.
Medchemexpress LLC HPK1-IN-4 | 2739844-28-9 | 99.1% | 434.49 | 50 MG
HPK1-IN-4 is a potent HPK1 (MAPK41) inhibitor with an IC50 of 0.061 nM. It serves as a preclinical immunotherapy tool compound for research applications.
- Potent HPK1 (MAPK41) inhibitor
- IC50 of 0.061 nM
- Targets MAP4K
- Affects the MAPK/ERK pathway
- Preclinical immunotherapy tool compound
Apexbio Technology LLC SM-102,25mg CAS# 2089251-47-6
Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC BSJ-02-162 (CDK4/6-IN-11) | 2139329-47-6 | 98.1% | C43H49N11O7 | 50 MG
CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader. It is composed of a thalidomide-based E3 ligase ligand, a target protein ligand (Palbociclib), and a PROTAC linker. The E3 ligase ligand and linker can combine to form Thalidomide-NH-amido-C4-Br. The product is intended for research use only.
- Potent PROTAC CDK4/6 degrader, effectively degrades CDK4/6.
- Composed of well-defined components including a thalidomide-based E3 ligase ligand, Palbociclib as a target protein ligand, and a PROTAC linker.
- High purity of 98.07% ensures reliable experimental results.
- Available in various quantities, ranging from 5 mg to 500 mg, catering to different research needs.
- Detailed documentation including Data Sheet, SDS, COA, HNMR, RP-HPLC, MS, and Handling Instructions are available.
Medchemexpress LLC (4-NH2)-Exatecan | 2495742-21-5 | 99.9% | C23H21N3O4 | 50 MG
(4-NH2)-Exatecan is a topoisomerase inhibitor and a derivative of Exatecan. It can be utilized in the synthesis of antibody-drug conjugates (ADCs). It contains a linker for connecting to a Ligand Unit, where the linker is attached in a cleavable manner to the amino residue, characterized by the addition of an amino (NH2) functional group at the 4th position of the parent molecule.
- A topoisomerase inhibitor
- Derivative of Exatecan
- Can be utilized in the synthesis of antibody-drug conjugates (ADCs)
- Contains a linker for connecting to a Ligand Unit
- Linker is attached in a cleavable manner to the amino residue
- Characterized by the addition of an amino (NH2) functional group at the 4th position
Enzo Life Sciences Furoxan (10mg). CAS: 125520-62-9
A novel NO donor which only releases NO in the presence of thiols. It is a potent vasodilator and inhibitor of platelet aggregation. Alternative name: 4-Phenyl-3-furoxancarbonitrile. Purity: ≥99% (HPLC). Solubility: Soluble in ethanol (25 mg/ml) or DMSO (25 mg/ml). Long Term Storage: -20°C.
Matrix Scientific 2-CHLORO-4,5-DIFLUOROBENZEN-1G
2-Chloro-4,5-difluorobenzenesulfonyl chloride, 1g,C6H2Cl2F2O2S, MFCD02091388, mw 247.05, [67475-58-5]
Matrix Scientific 3-FLUOROPHENYLBORONIC ACID-5G
3-Fluorophenylboronic acid, 97%; 5g,C6H6BFO2, MFCD00236042, mw 139.92, [768-35-4]
eMolecules Octadecyltriethoxysilane, tech. | 7399-00-0 | MFCD00039875 | 25g
Oakwood Chemical | Octadecyltriethoxysilane, tech. | 25g | 537724944 | S12300 | | 7399-00-0 | MFCD00039875 | 416.762 | C24H52O3Si
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Medchemexpress LLC Sertindole-d4 | 1794737-42-0 | 98.6% | C24H22D4ClFN4O | 1 MG
Sertindole-d4 is a deuterium-labeled form of Sertindole, a well-known neuroleptic medication. This compound is primarily used in research applications, offering stable isotopic labeling for various analytical techniques. It is particularly valuable as a tracer for quantitation during drug development and can serve as an internal standard for precise quantitative analysis using methods like NMR, GC-MS, or LC-MS. Deuterium substitution can also influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled compound for research.
- Acts as a tracer in drug development processes.
- Suitable as an internal standard for quantitative analysis.
- Potential for studying pharmacokinetic and metabolic profiles.
- Useful in NMR, GC-MS, and LC-MS applications.
Medchemexpress LLC PRX-07034 hydrochloride | 903580-39-2 | 98.97% | C21H29Cl2N3O4S | 100 MG
PRX-07034 hydrochloride is a potent and highly selective 5-HT6 receptor antagonist, exhibiting a Ki of 4-8 nM and an IC50 of 19 nM. This compound is valuable for research focused on enhancing working memory and cognitive flexibility.
- Highly selective 5-HT6 receptor antagonist.
- Demonstrates Ki of 4-8 nM and IC50 of 19 nM for 5-HT6 receptor.
- Supports research in enhancing working memory and cognitive flexibility.
- Shows ≥100-fold selectivity for 5-HT6 receptor over 68 other GPCRs, ion channels, and transporters.
- Inhibits multiple 5-HT and dopamine receptors at varying concentrations.
- Enhances delayed spontaneous alternation and strategy switching in animal models.
![eMolecules Medchem Express / KRN5 / 5mg / 446260167 / HY-112126 / / 1800465-47-7 / [null] / 459.473 / C27H22FNO5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502447284.PNG-250.jpg)
eMolecules Medchem Express / KRN5 / 5mg / 446260167 / HY-112126 / / 1800465-47-7 / [null] / 459.473 / C27H22FNO5
Medchem Express / KRN5 / 5mg / 446260167 / HY-112126 / / 1800465-47-7 / [null] / 459.473 / C27H22FNO5
Medchemexpress LLC PRL-3 Inhibitor I | 893449-38-2 | 99.10% | 485.21 | 50 MG
PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM, and it reduces invasion in cell-based assays.
- Potent PRL-3 inhibitor with an IC50 of 0.9 μM.
- Reduces invasion in cell-based assays.
- Chemical formula: C17H11Br2NO2S2
- Molecular weight: 485.21
- Appearance: Light yellow to green yellow solid.
- Soluble in DMSO at 41.67 mg/mL.
- Insoluble in H2O.
- Solid storage: 4°C, protected from light.
- Solution storage: -80°C for 6 months or -20°C for 1 month, protected from light.
Medchemexpress LLC HY-14715B 5mg Medchemexpress, CCT241533 (hydrochloride) CAS:1431697-96-9 Purity:>98%
Medchemexpress, HY-14715B 5mg CCT241533 (hydrochloride) CAS:1431697-96-9 CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 1-(3-Fluorophenyl)biguanide hydrochloride | 2267-49-4 | MFCD00203529 | 1g
Apollo Scientific | 1-(3-Fluorophenyl)biguanide hydrochloride | 1g | 562438949 | PC4149H | 97.000 | 2267-49-4 | MFCD00203529 | 231.660 | C8H11ClFN5
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