Organoheterocyclic compounds
3,4,7,8-Tetramethyl-1,10-phenanthroline 98.0+%, TCI America™
CAS: 1660-93-1 Molecular Formula: C16H16N2 Molecular Weight (g/mol): 236.318 MDL Number: MFCD00004974 InChI Key: NPAXPTHCUCUHPT-UHFFFAOYSA-N Synonym: 1,10-phenanthroline, 3,4,7,8-tetramethyl,3,4,7,8-tetramethylphenanthroline,3,4,7,8-tetramethyl-1, 10-phenanthroline,chembl99384,3,4,7,8-tetramethyl-1,10 phenanthroline,3,4,7,8-tetramethylpyridino 3,2-h quinoline,acmc-209dtn,3,4,7,8-me4phenan,bidd:gt0406,3,4,7,8-tetramethylphenantroline PubChem CID: 74265 IUPAC Name: 3,4,7,8-tetramethyl-1,10-phenanthroline SMILES: CC1=CN=C2C(=C1C)C=CC3=C(C(=CN=C32)C)C
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97.0+%, TCI America™
CAS: 1126-93-8 Molecular Formula: C8H17BO3 Molecular Weight (g/mol): 172.03 MDL Number: MFCD22054335 InChI Key: AWCHCIVACATJJS-UHFFFAOYSA-N Synonym: Ethoxyboronic Acid Pinacol Ester PubChem CID: 12727575 IUPAC Name: 2-ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane SMILES: CCOB1OC(C)(C)C(C)(C)O1
Medchemexpress LLC Isojacareubin | 50597-93-8 | 1 MG
Isojacareubin can be isolated from *Hypericum japonicum*. It is classified as a flavonoid (flavone) and appears as a light yellow to yellow solid. This compound is for research use only and not sold to patients.
- Covalently inhibits SARS-CoV-2 3CLpro
- Exhibits anti-helicobacter activity
- Inhibits PKC
- Suppresses hepatocellular carcinoma metastasis
- Induces apoptosis
Medchemexpress LLC Isojacareubin | 50597-93-8 | 5 MG
Isojacareubin, a compound isolated from Hypericum japonicum, demonstrates significant biological activities including covalent inhibition of SARS-CoV-2 3CLpro and anti-helicobacter properties. It also functions as a PKC inhibitor, capable of suppressing hepatocellular carcinoma metastasis and inducing apoptosis.
- Isolated from Hypericum japonicum
- Covalently inhibits SARS-CoV-2 3CLpro
- Possesses anti-helicobacter activity
- Inhibits PKC
- Suppresses hepatocellular carcinoma metastasis
- Induces apoptosis
Apexbio Technology LLC Ginsenoside Rd 52705-93-8 20mg
Ginsenoside Rd (CAS 52705-93-8) is a protopanaxadiol-type saponin derived from Panax ginseng This small molecule has been reported to modulate multiple signaling pathways associated with cell proliferation apoptosis and inflammation Experimental evidence suggests that Ginsenoside Rd can suppress tumor cell growth possibly by interfering with cell cycle progression and promoting apoptotic mechanisms Due to these properties it is utilized in biomedical research to investigate mechanisms underlying cancer development and to explore novel therapeutic approaches targeting tumor progression
Apexbio Technology LLC NVP-BSK805 1092499-93-8 50mg
NVP-BSK805 (CAS 1092499-93-8) is a selective Janus kinase 2 (JAK2) inhibitor It acts by blocking JAK2-mediated phosphorylation and subsequent activation of signal transducer and activator of transcription (STAT) proteins particularly STAT5 In kinase assays NVP-BSK805 potently inhibits wild-type JAK2 and the JAK2V617F mutant with IC50 values of approximately 0 58 nM and 0 56 nM respectively It suppresses STAT5 phosphorylation in JAK2-driven cell lines (CHRF-288-11 SET-2 and HEL) and inhibits STAT5 activation in animal models expressing JAK2V617F or treated with erythropoietin highlighting its utility in research on JAK2-related signaling and disorders
Medchemexpress LLC Pebrellin | 13509-93-8 | 374.34 | 1 MG
Pebrellin is a flavonoid that can be isolated from Mentha x piperita leaves. It is intended for research use only.
- Isolated from Mentha x piperita leaves.
- Available in various quantities for research needs.
- Detailed documentation provided including data sheets and safety data sheets.
- Quality control information, such as purity, is readily accessible.
- Storage and handling instructions are specified for product integrity.
- Supported by scientific publications.
Apexbio Technology LLC NVP-BSK805 1092499-93-8 5mg
NVP-BSK805 (CAS 1092499-93-8) is a selective Janus kinase 2 (JAK2) inhibitor It acts by blocking JAK2-mediated phosphorylation and subsequent activation of signal transducer and activator of transcription (STAT) proteins particularly STAT5 In kinase assays NVP-BSK805 potently inhibits wild-type JAK2 and the JAK2V617F mutant with IC50 values of approximately 0 58 nM and 0 56 nM respectively It suppresses STAT5 phosphorylation in JAK2-driven cell lines (CHRF-288-11 SET-2 and HEL) and inhibits STAT5 activation in animal models expressing JAK2V617F or treated with erythropoietin highlighting its utility in research on JAK2-related signaling and disorders
Apexbio Technology LLC NVP-BSK805 1092499-93-8 10mg
NVP-BSK805 (CAS 1092499-93-8) is a selective Janus kinase 2 (JAK2) inhibitor It acts by blocking JAK2-mediated phosphorylation and subsequent activation of signal transducer and activator of transcription (STAT) proteins particularly STAT5 In kinase assays NVP-BSK805 potently inhibits wild-type JAK2 and the JAK2V617F mutant with IC50 values of approximately 0 58 nM and 0 56 nM respectively It suppresses STAT5 phosphorylation in JAK2-driven cell lines (CHRF-288-11 SET-2 and HEL) and inhibits STAT5 activation in animal models expressing JAK2V617F or treated with erythropoietin highlighting its utility in research on JAK2-related signaling and disorders
Medchemexpress LLC Pebrellin | 13509-93-8 | 374.34 | 5 MG
Pebrellin is a flavonoid that can be isolated from *Mentha x piperita* leaves. It is for research use only and not sold to patients.
- Flavonoid isolated from Mentha x piperita leaves
- For research use only
- Purity: 98.51%
- Appearance: Solid
- Color: Light yellow to yellow
- Structure classification: Flavonoids, Flavones
- Initial source: Plants (Leguminosae, *Acacia farnesiana (Linn.) Willd.*), Plants (Labiatae)
- Related to inflammation or immune system disease
- Natural product standard
- Inhibitor
Medchemexpress LLC Rosarin | 84954-93-8 | 428.43 | 1 MG
Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. It exhibits anti-inflammatory and neuroprotective effects, suppressing the expression of proinflammatory factors such as iNOS, IL-1β, and TNF-α in the kidney and prefrontal cortex of the brain in mice.
- Isolated from Rhodiola rosea.
- Exhibits anti-inflammatory effects.
- Exhibits neuroprotective effects.
- Suppresses expression of proinflammatory factors such as iNOS, IL-1β, and TNF-α.
- Pretreatments with Rosarin can suppress iNOS and cytokine expression in murine BV2 cells.
Medchemexpress LLC Dipivefrin hydrochloride | 64019-93-8 | 98.40% | 50 MG
Dipivefrin hydrochloride is an antiglaucoma proagent that is hydrolyzed to the active compound, epinephrine, by esterases in the cornea. This compound induces enhancement of memory involving central beta- but not alpha-adrenergic mechanisms. It is intended for research use only.
- Acts as an antiglaucoma proagent
- Hydrolyzed to epinephrine in the cornea
- Enhances memory
- Involves central beta-adrenergic mechanisms
- Suitable for in vitro and in vivo studies
- Provided as a solid form
- Soluble in DMSO and water
Medchemexpress LLC Pentosan Polysulfate (Sodium) | 140207-93-8 | 5 MG
Pentosan Polysulfate Sodium is an orally bioavailable, semi-synthetic medication with anti-inflammatory, pro-chondrogenic, and potent anti-HIV properties. It is used for the treatment of interstitial cystitis and is suitable for research applications.
- Inhibits HIV-1 activity and antigen expression
- Suppresses NF-κB and decreases proinflammatory actions of TNFα
- Reduces MCP-1 production stimulated by high glucose and advanced glycation end products (AGEs)
- Decreases interstitial inflammation and glomerulosclerosis in nephrectomized rats
- Preserves renal function and reduces albuminuria
- Mitigates severity of renal lesions, including tubulointerstitial inflammation
- Reduces upregulation of TNFα and proinflammatory genes in aging diabetic kidneys
Sigma Aldrich Fine Chemicals Biosciences RO-3306 | 872573-93-8 | MFCD17392573 | 5mg
RO-3306 | Purity: 98% | Mol Wt: 351.45 | 872573-93-8 | MFCD17392573 | 5mg
Medchemexpress LLC Falnidamol | 196612-93-8 | 99.4% | 387.84 | 25 MG
Falnidamol | 196612-93-8 | 99.4% | 387.84 | 25 MG