Organooxygen compounds
Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.8% | C9H12Cl2N4O2 | 25 MG
Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) used for cancer research. It has antiangiogenic effects and inhibits the proliferation of endothelial cells. Tipiracil also acts as a potent inhibitor of thymidine phosphorylase, an enzyme that degrades FTD.
- Thymidine phosphorylase inhibitor (TPI)
- Used for cancer research
- Antiangiogenic effect
- Inhibits proliferation of endothelial cells
- Potent inhibitor of thymidine phosphorylase
- Enzyme degrades FTD
Medchemexpress LLC Voreloxin hydrochloride | 175519-16-1 | 99.6% | 437.90 | 25 MG
Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA double-strand breaks, G2 arrest, and apoptosis.
- Induces G2 arrest partially through topoisomerase II in A549 lung cancer cell line.
- Cytotoxic activity requires DNA intercalation.
- Exhibits potent cytotoxic activity in AML cell lines, including MV4-11 and HL-60.
- Shows additive or synergistic activity in acute leukemia cell lines when combined with cytarabine.
- Causes accumulation of cells in the S and G2 phases of the cell cycle.
- Induces bone marrow aplasia in vivo when combined with cytarabine.
Medchemexpress LLC Terazosin hydrochloride dihydrate | 70024-40-7 | 99.5% | 1 ML
Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive, orally active α1-adrenoceptor antagonist. It functions by relaxing blood vessels and aiding in the opening of the bladder. This compound has potential applications in the treatment of benign prostatic hyperplasia (BPH) and high blood pressure. This product is for research use only.
- Competitive α1-adrenoceptor antagonist
- Relaxes blood vessels
- Aids in opening the bladder
- Potential for treating benign prostatic hyperplasia (BPH)
- Potential for treating high blood pressure
- Does not differentiate cloned α1-adrenoceptor subtypes
- Can promote stone discharge in the treatment of ureteral stones
- Reportedly safe and effective for distal ureteral stones, especially those >5 mm
Medchemexpress LLC Alectinib Hydrochloride | 1256589-74-8 | 99.9% | 200 MG
Alectinib (CH5424802; RO5424802; RG7853) Hydrochloride is a potent, selective, and orally available ALK inhibitor. It has an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
- Potent and selective ALK inhibitor
- Orally available
- Effective central nervous system (CNS) penetration
- Inhibits ALK F1174L and ALK R1275Q
Medchemexpress LLC Amprolium hydrochloride | 137-88-2 | 98.79% | 250 MG
Amprolium hydrochloride is an anti-parasitic drug that is taken orally and acts as an antagonist to thiamine in intestinal absorption. It is for research use only and not sold to patients.
- Acts as an antagonist to thiamine in intestinal absorption
- Targets Coccidia
- Suitable for in vivo and in vitro applications
- For research use only
Medchemexpress LLC 9h-Carbazole-3-methanamine, 9-ethyl-N-methyl-, hydrochloride (1:1) | 1050480-30-2 | 99.3% | 274.79 | 1 ML
PhiKan 083 hydrochloride is a carbazole derivative that binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells.
- Slows down its thermal denaturation rate.
Medchemexpress LLC PRX-07034 hydrochloride | 903580-39-2 | 98.97% | C21H29Cl2N3O4S | 1 ML
PRX-07034 hydrochloride | 903580-39-2 | 98.97% | C21H29Cl2N3O4S | 1 ML
Medchemexpress LLC EPZ020411 hydrochloride | 2070015-25-5 | 98.2% | 50 MG
EPZ020411 hydrochloride is a potent and selective inhibitor of protein arginine methyltransferase 6 (PRMT6) with an IC50 of 10 nM. It exhibits over 10-fold selectivity for PRMT6 compared to PRMT1 and PRMT8. This compound is valuable for cancer research and has demonstrated the ability to decrease H3R2 methylation in A375 cells, as well as reduce neomycin- and cisplatin-induced cell apoptosis, thereby increasing hair cell survival.
- Selective inhibitor of PRMT6
- IC50 of 10 nM for PRMT6
- Over 10-fold selectivity for PRMT6 over PRMT1 and PRMT8
- Can be used for cancer research
- Decreases H3R2 methylation in A375 cells
- Reduces neomycin- and cisplatin-induced cell apoptosis
- Increases hair cell survival
Medchemexpress LLC (R)-(-)-littorine hydrochloride | 21956-47-8 | MFCD30725552 | 99.6% | 325.83 | C17H24ClNO3 | 1 MG
Littorine hydrochloride is a research-grade tropane alkaloid provided as the hydrochloride salt for laboratory use. It is reported in plant species such as Anthocercis fittorea and Datura species and is intended for analytical reference, assay development, and natural product research.
- Supplied as the hydrochloride salt suitable for analytical work.
- Molecular formula corresponds to C17H24ClNO3 (hydrochloride form).
- Offered in small, vial quantities appropriate for reference and assay applications.
- Intended for research use only; not for human or clinical use.
- Consult the SDS and certificate of analysis for storage, handling, and lot-specific purity.
Medchemexpress LLC Pholedrine (hydrochloride) | 877-86-1 | 99.6% | 10 MG
Pholedrine hydrochloride is the hydrochloride salt of pholedrine, an indirectly acting sympathomimetic amine used in research on adrenergic receptors and cardiovascular responses. It is supplied as a solid research chemical with recommended storage at 4°C (sealed), and solution storage at -80°C for long-term preservation.
- Hydrochloride salt form for improved stability.
- Used to study adrenergic receptor activity and cardiovascular effects.
- Available in small milligram pack sizes suitable for research, e.g. 10 MG.
- Molecular formula C10H16ClNO; molecular weight 201.69 g/mol.
- Recommended storage: 4°C sealed; in solution store at -80°C for long-term.
Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | MFCD17215959 | 99.9% | 369.89 | C18H28ClN3O3 | 10 MG
VU0357017 hydrochloride is a brain-penetrant, selective allosteric agonist of the M1 muscarinic acetylcholine receptor used as a research tool to probe M1 receptor pharmacology and signaling. Supplied as the hydrochloride salt, the compound is characterized by a defined molecular weight and high reported purity.
- Potent M1 allosteric agonist with reported EC50 ≈ 477 nM.
- Brain-penetrant small molecule suitable for in vitro and in vivo studies.
- High chemical purity as provided by manufacturer.
- Provided as a hydrochloride salt for improved solubility.
- Available in small research pack sizes for laboratory use.
Aobchem 1-(3-Methylphenyl)ethanol | ≥95% | CAS 7287-81-2 | C9H12O | 5g
1-(3-Methylphenyl)ethanol | ≥95% | CAS 7287-81-2 | C9H12O | 5g