Organooxygen compounds
Medchemexpress LLC 18α-Glycyrrhetinic acid | 1449-05-4 | 470.68 | 50 MG
18α-Glycyrrhetinic acid is a diet-derived compound that functions as an inhibitor of NF-κB and an activator of proteasome. It acts as a pro-longevity and anti-aggregation factor in multicellular organisms and also induces apoptosis.
- Diet-derived compound
- Inhibitor of NF-κB
- Activator of proteasome
- Serves as a pro-longevity factor
- Acts as an anti-aggregation factor
- Induces apoptosis
eMolecules 26575-95-1 | Medchem Express | Alisol B 23-acetate | 10mg | 446275403 | HY-N0805 | MFCD00210473 | 514.747 | C32H50O5
Medchem Express | Acetaminophen-d4 | 5mg | 713707082 | HY-66005S | 64315-36-2 | MFCD01317366 | 155.189 | C8H9NO2
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Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 5 MG
Gypenoside XLIX, isolated from Gynostemma pentaphyllum, is a multifunctional bioactive compound. It acts as a PPAR-α agonist and binds to SIRT1, inhibiting TLR4-mediated NF-κB signaling and reducing ROS accumulation.
- Targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy.
- Inhibits apoptosis, pyroptosis, autophagy, and lipid peroxidation.
- Alleviates sepsis-induced splenic injury, inflammation, and oxidative stress.
- Mitigates sepsis-associated encephalopathy by targeting PPAR-α.
- Prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death.
- Inhibits vascular cell adhesion molecule-1 expression in human endothelial cells.
- Used in research for acute liver/lung injury, cardiomyopathy, and acute kidney injury.
Medchemexpress LLC Benzoylpaeoniflorin | 38642-49-8 | 584.57 | 50 MG
Benzoylpaeoniflorin | 38642-49-8 | 584.57 | 50 MG
Medchemexpress LLC HY-77434 10mg Medchemexpress, 9-Dihydro-13-acetylbaccatin III CAS:142203-65-4 Purity:>98%
Medchemexpress, HY-77434 10mg 9-Dihydro-13-acetylbaccatin III CAS:142203-65-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 39262-14-1 | Medchem Express | Ginsenoside C-K | 5mg | 446275532 | HY-N0904 | MFCD07772261 | 622.884 | C36H62O8
Medchem Express | MF63 | 5mg | 446262666 | HY-13283 | 892549-43-8 | MFCD18384972 | 378.820 | C23H11ClN4
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eMolecules 472-11-7 | Medchem Express | Ruscogenin | 5mg | 482204569 | HY-N0496 | MFCD00210550 | 430.629 | C27H42O4
Medchem Express | (R)-()-Bay-K-8644 | 5mg | 446264991 | HY-15125 | 98791-67-4 | MFCD00153768 | 356.301 | C16H15F3N2O4
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Medchemexpress LLC HY-N0629 5mg Medchemexpress, Maslinic acid CAS:4373-41-5 Purity:>98%
Medchemexpress, HY-N0629 5mg Maslinic acid CAS:4373-41-5 Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α , which is required for p65 activation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Ursodiol 128-13-2 1g
Ursodiol (CAS 128-13-2) also known as ursodeoxycholic acid is a bile acid commonly utilized in the treatment of primary biliary cholangitis (PBC) Mechanistically ursodiol interferes with the progression of PBC and enhances patient survival In cellular models ursodiol has been shown to dose-dependently inhibit the viability of HepG2 and BEL7402 hepatoma cells with IC50 values of 0 92 mmol/L and 0 86 mmol/L respectively while significantly promoting apoptosis in these lines Western blot analyses reveal that ursodiol downregulates the expression of cell cycle regulators including cyclin D1 cyclin D3 Cdk2 and Cdk4 Its antiproliferative and pro-apoptotic properties underscore its value in studies of liver disease and oncogenesis
Apexbio Technology LLC Rocuronium Bromide 119302-91-9 25mg
Rocuronium Bromide (CAS 119302-91-9) is an aminosteroid compound that functions as a non-depolarizing neuromuscular blocking agent It acts by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction thereby inhibiting acetylcholine-induced depolarization and subsequent muscle contraction In research settings Rocuronium Bromide is utilized to investigate neuromuscular transmission and to model pharmacological blockade of skeletal muscle activity supporting studies in anesthesia muscle physiology and synaptic transmission mechanisms
Medchemexpress LLC 11-keto-beta-boswellic acid | 17019-92-0 | MFCD06656312 | 99.9% | 470.68 g/mol | C30H46O4 | 10 MG
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid isolated from Boswellia species with reported anti-inflammatory, metabolic, and neuroprotective activities. It modulates 5-lipoxygenase and NF-κB signaling and is commonly used in preclinical studies. Soluble in DMSO for in vitro use.
- Pentacyclic triterpenic acid with anti-inflammatory activity.
- Demonstrated inhibition of 5-lipoxygenase and NF-κB pathways.
- Reported DPP-4 modulation and neuroprotective effects in animal models.
- High purity suitable for biochemical and cell-based assays.
- Soluble in DMSO; multiple in vivo formulation protocols reported.
![eMolecules 77-52-1 | URSOLIC ACID | AstaTech | MFCD00009621 | 456.711 | C30H48O3 | 95.000 | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O | 25g | 449731464](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502170187.JPG-250.jpg)
eMolecules 77-52-1 | URSOLIC ACID | AstaTech | MFCD00009621 | 456.711 | C30H48O3 | 95.000 | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O | 25g | 449731464
URSOLIC ACID | AstaTech | 77-52-1 | MFCD00009621 | 456.711 | C30H48O3 | 95.000 | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O | 25g | 449731464
eMolecules 6294-40-2 | 1-Bromo-4-methylcyclohexane | MFCD00014282 | 5g
Combi-Blocks | 1-Bromo-4-methylcyclohexane | 5g | 448007489 | QF-3536 | 95.000 | 6294-40-2 | MFCD00014282 | 177.085 | C7H13Br
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Apexbio Technology LLC Triamcinolone 124-94-7 50mg
Triamcinolone (124-94-7) is a small-molecule agonist targeting intracellular glucocorticoid receptors (GR) It is designed to modulate the transcriptional regulation of genes involved in inflammation immune responses cellular proliferation vascular permeability and angiogenesis thereby regulating multiple cellular and immunological pathways Triamcinolone exerts its biological activity primarily through binding to GR and modulating downstream gene expression In cell-based GR assays Triamcinolone demonstrates potent receptor binding with reported IC50 values typically ranging from 0 5 to 5 nM Based on these pharmacological properties Triamcinolone holds research potential in experimental models of dermatological inflammation ophthalmic inflammation autoimmune conditions and investigations of GR-mediated signal transduction and immunoregulatory pathways