Phenylpropanoids and polyketides
Medchemexpress LLC Coumarin (Standard) | 91-64-5 | 146.14 | 100 MG
Coumarin (Standard) is the analytical standard of Coumarin, intended for research and analytical applications. It is a potent, orally active anti-inflammatory agent, also exhibiting antinociceptive, antibacterial, antifungal, and anticancer activities.
This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Intended for research and analytical applications.
- Functions as an anti-inflammatory agent.
- Exhibits antinociceptive effects.
- Shows antibacterial activity.
- Displays antifungal activity.
- Demonstrates anticancer activity.
- Suitable for HPLC, GC, and MS research.
Apexbio Technology LLC Tacrolimus (FK506) 104987-11-3 200mg
Tacrolimus (FK506) is a macrolide immunosuppressant that acts as a potent inhibitor of calcineurin thereby selectively suppressing T-cell activation Mechanistically tacrolimus forms a complex with FKBP12 protein which binds to calcineurin and inhibits phosphatase activity subsequently blocking the transcription and secretion of cytokines notably interleukin-2 (IL-2) IL-3 IL-4 and interferon- Tacrolimus demonstrates an IC50 range between 0 1 1 nM in inhibiting IL-2 secretion in cellular assays Due to this mode of action it is commonly utilized in biomedical research focusing on T-cell response modulation cytokine-mediated signaling pathways transplantation immunology and autoimmune disease models both in vitro and in animal transplant studies
Medchemexpress LLC Tacrolimus | 104987-11-3 | MFCD00869680 | ≥98% | 804.01 | 1 G
Tacrolimus (FK506) is a macrocyclic lactone that binds to FK506 binding protein (FKBP) to form a complex. It inhibits calcineurin phosphatase, which in turn inhibits T-lymphocyte signal transduction and IL-2 transcription, exhibiting immunosuppressive properties.
- Binds to FK506 binding protein (FKBP)
- Inhibits calcineurin phosphatase
- Inhibits T-lymphocyte signal transduction
- Inhibits IL-2 transcription
- Possesses immunosuppressive properties
Chem-Impex International, Inc. L-(-)-3-Phenyllactic acid | 20312-36-1 | MFCD00004244 | 100G
L-(-)-3-Phenyllactic acid, 20312-36-1, MFCD00004244, 100G
Cayman Chemical NIcotIflorIn 10mg
A flavonoid; scavenges DPPH and ABTS radicals (EC50s = 0.52 and 0.48 mg/ml, respectively) in cell-free assays; prevents hydrogen peroxide-induced decreases in tyrosine hydroxylase activity in PC12 cells and cell death in isolated rat mesencephalic neurons at 1 µM; decreases infarct size by 24.5, 45.8, and 63.2% at 2.5, 5, and 10 mg/kg, respectively, in a rat model of cerebral ischemia-reperfusion injury induced by transient MCAO
Medchemexpress LLC HY-N0875 5mg Medchemexpress, IKarisoside A CAS:55395-07-8 Purity:>98%
Medchemexpress, HY-N0875 5mg IKarisoside A CAS:55395-07-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-N0423 100mg Medchemexpress, Sophoricoside CAS:152-95-4 Purity:>98%
Medchemexpress, HY-N0423 100mg Sophoricoside CAS:152-95-4 Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and has anti-inflammatory, anti-cancer and immunosuppressive effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Naringin S2329-500mg
Naringin (Naringoside) is a flavanone glycoside which exerts a variety of pharmacological effects such as antioxidant activity blood lipid lowering anticancer activity and inhibition of cytochrome P450 enzymes
Sigma Aldrich Fine Chemicals Biosciences Naringin >=95% (HPLC) | 10236-47-2 | MFCD00148888 | 100G
Naringin >=95% (HPLC) | Purity: >=95% (HPLC) | Mol Wt: 580.53 | 10236-47-2 | MFCD00148888 | 100G
Apexbio Technology LLC AMG 487 473719-41-4 50mg
AMG 487 (CAS 473719-41-4) is a selective small molecule antagonist targeting chemokine receptor CXCR3 a G protein-coupled receptor involved in immune cell migration It competitively inhibits CXCR3 binding to its cognate chemokines including IP-10 and ITAC with IC50 values reported at approximately 8 nM and 8 2 nM respectively Cell-based assays indicate AMG 487 can effectively impede IP-10 ITAC and MIG-mediated chemotaxis and ITAC-induced calcium mobilization AMG 487 is metabolized via CYP3A4 and CYP3A5 to metabolites one of which (M2) inhibits CYP3A Given these characteristics AMG 487 provides a valuable pharmacological tool for investigating CXCR3 functions in inflammatory and immunological research