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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Harmol (Methylpyridoindolol) is a (beta)-carboline isolated from nature. purity: 98%
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4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis, and a synthetic analogue of flavanone. It is used in research into hepatic steatosis and dyslipidemia.
Purity of 99.75%
Molecular weight of 240.25 g/mol
Chemical formula C15H12O3
Classified as a flavonoid, flavanone, phenol, and monophenol
Isolated from Aspergillus niger
Provided as a 10 mM solution in DMSO
Store powder at -20°C for 3 years, or 4°C for 2 years
Store solution at -80°C for 6 months, or -20°C for 1 month
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PSB-SB-487 is a small-molecule research compound that functions as a potent GPR55 antagonist and a CB2 receptor agonist. It is intended for research use only and is employed in studies of metabolic disorders, neurodegeneration, pain mechanisms, and oncology. Reported potency includes a GPR55 IC50 of 0.113 μM and a human CB2 Ki of 0.292 μM.
Potent GPR55 antagonist and CB2 agonist with reported potency values.
Molecular formula C26H32O4; molecular weight 408.53 g/mol.
High purity: 98.0%.
Appearance: white to off-white solid.
Recommended storage: powder at -20°C for long term, 4°C for short term; in solvent at -80°C.
Supplied in small milligram quantities suitable for in vitro research and pharmacology.
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AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
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Naphthol-AS-MX-phosphate research grade Selective substrate of alkaline phosphatase. Suitable for dye coupling. Fast Blue RR (1). Fast Red TR-salt (cat. no. 21317) (2). Size - 250MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 30002.01 CAS No.
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7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). It displays therapeutic efficacy toward various neurological diseases.
Protects primary cortical neurons and locus coeruleus neurons from Aβ-induced toxicity
Promotes dendritic growth and synaptogenesis
Prevents synaptic loss and memory deficits in an Alzheimer's Disease model
Activates TrkB in the brain
Inhibits kainic acid-induced toxicity
Decreases infarct volumes in stroke
Neuroprotective in a Parkinson disease model
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Apigenin-7-O-sulfate is a major flavonoid which is found to be a distinctive feature of plants from the Bay of Cadiz and can be extracted from these plants[1]
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A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
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MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.