Phenylpropanoids and polyketides
Medchemexpress LLC HY-B0275 50mg Medchemexpress, Oxytetracycline CAS:79-57-2 Purity:>98%
Medchemexpress, HY-B0275 50mg Oxytetracycline CAS:79-57-2 Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Catechin 7-O-β-D-glucopyranoside | 65597-47-9 | 452.41 | 1 MG
Catechin 7-O-β-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. It demonstrates antioxidant and anti-inflammatory activities, and mitigates mitochondrial dysfunction. This product can be utilized in research pertaining to intestinal inflammatory diseases.
- Exhibits antioxidant and anti-inflammatory activities
- Attenuates mitochondrial dysfunction
- Protective effect against Streptozotocin-induced cell damage
- Mild protective effect against LPS/D-GalN induced lethality in mice
- Prevents intestinal inflammatory damages in rat colitis models
Medchemexpress LLC Apigenin | 520-36-5 | 270.24 | 1 G
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor that inhibits cytochrome P450 2C9 in a purified enzyme system. It demonstrates dose- and time-dependent inhibition of cell proliferation in SGC-7901 cells.
- Competitive CYP2C9 inhibitor with a Ki of 2 μM.
- Inhibits cytochrome P450 2C9 in a purified, reconstituted enzyme system.
- Demonstrates inhibition of cell proliferation in SGC-7901 cells in a dose- and time-dependent manner.
- Achieves growth inhibition rates of 38%, 71%, and 99% at 20, 40, and 80 μM, respectively, on the 7th day.
- Cloning efficiency in SGC-7901 cells treated with 80 μM for 24 and 48 hours was 9.8% and 5%, respectively.
Medchemexpress LLC Dihydrocoumarin | 119-84-6 | 148.16 | 100 G
Dihydrocoumarin is a compound found in *Melilotus officinalis*. It is a yeast Sir2p inhibitor and also inhibits human SIRT1 and SIRT2. It is suitable for laboratory research and includes the following features and benefits:
- Inhibits yeast Sir2p
- Inhibits human SIRT1 and SIRT2
- Increases cytotoxicity in the TK6 cell line
- Increases apoptosis in the TK6 cell line
- Increases p53 lysine 373 and 382 acetylation
Medchemexpress LLC Isovitexin 7-O-rutinoside | 212271-10-8 | 740.66 | 5 MG
Isovitexin 7-O-rutinoside is an anti-inflammatory agent that can be isolated from the Mongolian anti-hepatic plant Dianthus versicolor.
- Acts as an anti-inflammatory agent
Medchemexpress LLC 7-Methylcoumarin | 2445-83-2 | 50 G
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. It acts as a mechanism-based inhibitor for CYP2A6. This compound has been shown to significantly decrease alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, while also restoring total protein (TP) and albumin (TA) levels in serum and preventing oxidative stress. Additionally, 7-Methylcoumarin can reduce the mitotic activity of *A. sativum* promeristem.
- Potent hepatoprotective properties.
- Antioxidant properties.
- Mechanism-based inhibitor for CYP2A6.
- Decreases ALT, AST, and serum bilirubin in rats with CCl4-induced liver damage.
- Restores total protein and albumin levels in serum.
- Prevents oxidative stress.
- Can decline mitotic activity of *A. sativum* promeristem.
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 1 ML
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2, COX-2, and 5-LOX, and is orally active.
- Inhibits nicotine-induced cytotoxicity and reduces ROS production in renal cells
- Inhibits EV71 3C protease, blocking viral replication
- Decreases malondialdehyde and ROS levels, increases SOD and GSH levels in HepG2 cells
- Inhibits inflammatory cytokines and reduces myocardial injury markers in rat models
- Ameliorates Paclitaxel or Vinorelbine-induced neuropathic pain in mice models
- Reduces fat accumulation, improves hepatic steatosis and oxidative stress in NAFLD models
TARGETMOL CHEMICALS INC CINANSERIN HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. purity: 99%
Medchemexpress LLC Genistein | 446-72-0 | 98.7% | C₁₅H₁₀O₅ | 100 MG
Genistein (Standard) is an analytical standard used in research and analytical applications. This soy isoflavone functions as a multiple tyrosine kinases inhibitor, notably EGFR, and demonstrates chemotherapeutic properties against various cancers by influencing apoptosis, cell cycle regulation, angiogenesis, and metastasis.
- Analytical standard for Genistein
- Intended for research and analytical applications
- Functions as a multiple tyrosine kinases inhibitor (e.g., EGFR)
- Acts as a chemotherapeutic agent against different types of cancer
- Alters apoptosis, cell cycle, and angiogenesis
- Inhibits metastasis
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques like HPLC, GC, and MS
Medchemexpress LLC 6-Methylcoumarin | 92-48-8 | 160.17 | 1 ML
6-Methylcoumarin is a synthetic fragrance primarily used in cosmetics. It has been reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models. Studies show that when HaCaT cells are treated with 6-Methylcoumarin and UVA irradiation, it produces γ-H2AX-positive cells at concentrations from 100 nM.
- Synthetic fragrance widely used in cosmetics.
- Reported to be almost nonphototoxic in epidermal tissue and cell culture phototoxicity test models.
Chem-Impex International, Inc. 3-(4'-Hydroxyphenyl)propionic acid | 501-97-3 | MFCD00002778 | 100G
3-(4'-Hydroxyphenyl)propionic acid, 501-97-3, MFCD00002778, 100G