Phenylpropanoids and polyketides
TARGETMOL CHEMICALS INC trans-Cinnamic acid 1G
Also available in 1 mL, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro. Purity 99.96%
TARGETMOL CHEMICALS INC Tacrolimus 100MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase. Purity 99.87%
Medchemexpress LLC (-)-Epigallocatechin-3-O-(4-O-methyl)gallate | 224434-07-5 | MFCD06799453 | 472.40 | 1 MG
(-)-Epigallocatechin-3-O-(4-O-methyl)gallate is an orally active catechin derivative found in Taiwanese oolong tea. It can inhibit histamine release and exhibits anti-inflammation and anti-allergic effect. It can be used for researches of immunology and inflammation, such as type I allergic.
- Inhibits histamine release from IgE/antigen-activated mouse mast cells (45% inhibition rate at 50 μg/mL).
- Exhibits excellent plasma stability (only 10% degradation rate at 500 μg/mL for 15 mins).
- Significantly inhibits type I allergic reactions in mice sensitized with ovalbumin (5-50 mg/kg, i.g.).
- Achieved approximately 50% inhibition rate of abdominal wall blue dye permeation at 10 mg/kg in animal models.
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 100 G
4-(3-Fluorobenzyloxy)benzaldehyde is a chemical compound that serves as a drug intermediate. It is used in the synthesis of various active compounds for research purposes.
- Solid appearance
- Functions as a drug intermediate
- Suitable for the synthesis of active compounds
- For research use only
- Shipped at room temperature in continental US
- Store at 4°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | MFCD02605317 | 99.82% | C14H11FO2 | 50 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate used for the synthesis of various active compounds. This product is provided as a solid and is intended for research use only.
- Drug intermediate for synthesis of active compounds
- Provided as a solid
- For research use only
Medchemexpress LLC Myricitrin | 17912-87-7 | 99.8% | 464.38 | 25 MG
Myricitrin, a naturally occurring flavonoid, acts as an orally active nitric oxide (NO) and PKC inhibitor. It exhibits central nervous system activity, including anxiolytic-like effects. Myricitrin also possesses antioxidant, anti-inflammatory, antifibrotic, and anti-malarial properties.
- Orally active NO and PKC inhibitor.
- Central nervous system activity (anxiolytic-like action).
- Antioxidant effects (radical scavenger, metal-ion chelator).
- Anti-inflammatory effects.
- Antifibrotic effects.
- Anti-malarial effects (inhibits *Plasmodium falciparum* proliferation).
- Inhibits aldose reductase activity and low-density lipoprotein oxidation.
- Exhibits scavenging activity against DPPH, NO radicals, and H2O2.
- Inhibits TNFα production and enhances RANTES production in LPS-stimulated Raw264.7 cells.
Medchemexpress LLC Ferulic acid | 1135-24-6 | MFCD00004555 | 100.0 % | 194.18 | 25 MG
Ferulic acid (Standard) serves as the analytical standard for Ferulic acid, primarily intended for research and analytical applications. It is also recognized as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, exhibiting IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
- Analytical standard for Ferulic acid
- Intended for research and analytical applications
- Novel fibroblast growth factor receptor 1 (FGFR1) inhibitor
Apexbio Technology LLC 2-Methoxycinnamaldehyde 1504-74-1 100mg
2-Methoxycinnamaldehyde (CAS 1504-74-1) is a natural compound derived from cinnamon investigated for its biomedical properties Studies indicate that it disrupts mitochondrial membrane potential leading to mitochondrial dysfunction This effect is associated with the activation of caspase-3 and caspase-9 resulting in the induction of apoptosis and reduced cellular proliferation Additionally 2-Methoxycinnamaldehyde has been shown to inhibit the migration of human aortic smooth muscle cells in response to platelet-derived growth factor (PDGF) These attributes support its application in research exploring cancer cell apoptosis and vascular smooth muscle cell biology