Cobimetinib-d4 hydrochloride is a deuterated labeled version of Cobimetinib, a potent, selective, and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1. This compound is intended for research use only and not for sale to patients. Deuteration, the incorporation of stable heavy isotopes, is noted for its potential impact on the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.