Diterpenoids
Selleck Chemical LLC Docetaxel S1148-250mg
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Medchemexpress LLC HY-N0360 10mg Medchemexpress, Dihydrotanshinone I CAS:87205-99-0 Purity:>98%
Medchemexpress, HY-N0360 10mg Dihydrotanshinone I CAS:87205-99-0 Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC LDN-57444
LDN-57444 is a reversible competitive proteasome inhibitor for Uch-L1 with IC50 of 0 88 M 28-fold selectivity over isoform Uch-L3
AG Scientific Inc Aphidicolin, 1 MG
Aphidicolin is a reversible inhibitor of nuclear DNA replication in eukaryotes and some animal viruses. It interferes with dCTP-specific binding sites on DNA polymerase-alpha. It also works on other DNA polymerases, however it does not work on DNA polymerase-alpha. Viruses inducing DNA polymerase-alpha, such as Herpes simplex, can be affected by aphidicolin because of its mechanism. It could be used for clinical study. Isolated from Nigrospora oryzae.CAS Number: 38966-21-1Molecular Weight: 338.5Chemical Formula: C20H34O4Solubility: Methanol: Clear colorless solution at 10 mg/mlStorage Temperature: 2-8CResearch or further manufacturing use only, not for food or drug use.
Selleck Chemical LLC Paclitaxel S1150-1g
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Medchemexpress LLC HY-N0134 5mg Medchemexpress, Tanshinone I CAS:568-73-0 Purity:>98%
Medchemexpress, HY-N0134 5mg Tanshinone I CAS:568-73-0 Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC TANSHINONE IIA, 50 MG
MedChemExpress LLC| Tanshinone IIA | 50 mg | HY-N0135 | Purity 99.74% | 568-72-9 | MW: 294.34
Apexbio Technology LLC Cryptotanshinone 35825-57-1 20mg
Cryptotanshinone (CAS 35825-57-1) is a bioactive diterpene quinone derived from Salvia miltiorrhiza It modulates cellular signaling pathways by interacting with various molecular targets including components of the STAT3 signaling cascade thereby influencing transcriptional activity Studies indicate that cryptotanshinone alters gene expression profiles associated with cellular stress responses and apoptosis Due to its ability to regulate molecular pathways relevant to cancer biology and oxidative stress cryptotanshinone is widely utilized in biomedical research investigating mechanisms of tumor progression chemoprevention and cytoprotection
TARGETMOL CHEMICALS INC Paclitaxel 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy. Purity 99.92%
Cayman Chemical 10-acetyl Docetaxel 50mg
A derivative of paclitaxel and an inhibitor of microtubule depolymerization; inhibits calcium-induced depolymerization of calf brain MTP in a cell-free assay at 20 µM; cytotoxic to J774.2 cells (EC50 = 0.05 µM)
TARGETMOL CHEMICALS INC Docetaxel 500MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Docetaxel (RP-56976), a semi-synthetic analog of paclitaxel, is a microtubule depolymerization inhibitor (IC50=0.2 uM) that attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity. Purity 99.1%
AdipoGen (+)-Aphidicolin,Chemical. CAS: 38966-21-1
(+)-Aphidicolin, AdipoGen Life Sciences. Chemical. CAS: 38966-21-1. Formula: C20H34O4. MW: 338.5. Isolated from Phoma sp. BS 7210. Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.