Diterpenoids
Cayman Chemical -AphIdIcolIn 25mg
Peptde Sequence human FABP4 amno acds 103-118 To be used n conjuncton wth Cayman s FABP4 Polyclonal Antbody (tem No 10004944) to block proten-antbody complex formaton durng mmunochemcal analyss of FABP4
Cayman Chemical -AphIdIcolIn 5mg
A non-cytotoxc nhbtor of ACC and fatty acd synthess blocks the ncorporaton of radolabeled acetate nto palmtate at 1 Ug/ml reduces malonyl-CoA levels relatvely non-toxc to varous cancer cell lnes attenuates the nhbton of feedng observed when FASN nhbtors such as cerulenn and C75 are admnstered to obese ob/ob mce
Cayman Chemical Docetaxel-d9 1mg
An OX1R antagonist (KB 39 8 nM) selective for OX1R over OX2R (KB 1995 3 nM) reduces food intake and increases resting duration in rats as well as inhibits orexin-A-induced increases in food intake at 30 mg/kg inhibits orexin-A-induced increases in grooming time in rats at 10 mg/kg increases the seizure threshold in both the MEST and 6 Hz psychomotor seizure test in mice at 30 and 3 mg/kg respectively reduces morphine-induced analgesia in the formalin test in rats at 0 5-50 nmol i c v reduces acquisition and consolidation of spatial memory in the Morris water maze in rats when administered to the dentate gyrus at 1 5-6 g
Isophytol, 95%, Thermo Scientific™
CAS: 505-32-8 Molecular Formula: C20H40O Molecular Weight (g/mol): 296.539 MDL Number: MFCD00048380 InChI Key: KEVYVLWNCKMXJX-UHFFFAOYSA-N Synonym: isophytol,3,7,11,15-tetramethyl-1-hexadecen-3-ol,1-hexadecen-3-ol, 3,7,11,15-tetramethyl,2,6,10,14-tetramethylhexadec-15-en-14-ol,2,6,10-trimethyl-14-vinylpentadecan-14-ol,1-hexadecene-3-ol, 3,7,11,15-tetramethyl,1-phyten-3-ol,iso-phytol,dsstox_cid_5474 PubChem CID: 10453 IUPAC Name: 3,7,11,15-tetramethylhexadec-1-en-3-ol SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)(C=C)O
Thermo Scientific Chemicals Aphidicolin
CAS: 38966-21-1 Molecular Formula: C20H34O4 Molecular Weight (g/mol): 338.488 MDL Number: MFCD00083214 InChI Key: NOFOAYPPHIUXJR-APNQCZIXSA-N Synonym: aphidicolin,unii-192tj6pp19,ccris 1783,chembl29711,3r,4r,4ar,6as,8r,9r,11as,11bs-4,9-bis hydroxymethyl-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta a naphthalene-3,9-diol,9,15-cyclo-c,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, 3alpha,4alpha,5alpha,17alpha,+-aphidicolin,8,11a-methano-11ah-cyclohepta a naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, 3r-3-alpha,4-alpha,4a-alpha,6a-beta,8-beta,9-beta,11a-beta,11b-beta,+/--aphidicolin,aphidicolin, +/- PubChem CID: 457964 ChEBI: CHEBI:2766 SMILES: CC12CCC(C(C1CCC3C24CCC(C(C3)C4)(CO)O)(C)CO)O
Cayman Chemical Paclitaxel, 33069-62-4, 100 mg
Molecular Formula C47H51NO14, Purity ≥98%, Formula Weight 853.9, Synonyms: NSC 125973; A potent disruptor of microtubules used as a chemotherapeutic compound; inhibits growth of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas with IC50 values ranging from 2.5-7.5 nM; induces mitotic arrest and initiates apoptosis of cancer cells through multiple mechanisms.