Triterpenoids
Cayman Chemical Betulinic Aldehyde, Purity: ≥98%, CAS: 13159-28-9, 5 mg
A triterpenoid with diverse biological activities; active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively); inhibits dengue virus NS5 RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% at 5 and 10 μg/ml, respectively; inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively)
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.2% | 456.7 g/mol | C30H48O3 | 100 MG
Betulinic acid is a natural pentacyclic triterpenoid (CAS 472-15-1) provided as an analytical reference standard for research and analytical applications. It is used as a qualitative and quantitative standard in method development and validation for HPLC, GC, and MS, and is reported to have biological activities including anti-HIV, anti-malarial, anti-inflammatory, and anti-tumor effects.
- High reported purity for analytical applications.
- Suitable for HPLC, GC, and MS method development.
- Intended for qualitative and quantitative reference standards.
- Supplied as a solid reference material with defined sizes.
- Supports research into multiple biological activities.
Carbosynth LLC. FORSKOLIN 1000 MG
Forskolin | Molecular Weight: 410.5 g/mol | 66575-29-9 | MFCD00082317 | 1000 mg
Enzo Life Sciences Betulinic acid (~95%) (500mg). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 10mM (in 1mL DMSO), CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies
Medchemexpress LLC Lupeol (Clerodol; Monogynol B; Fagarasterol) | 545-47-1 | 426.72 | 25 MG
Lupeol is an active pentacyclic triterpenoid with anti-oxidant, anti-mutagenic, anti-tumor, and anti-inflammatory activities. It is also a potent androgen receptor (AR) inhibitor and is used for cancer research, particularly for androgen-dependent phenotype (ADPC) and castration-resistant phenotype (CRPC) prostate cancer.
- Active pentacyclic triterpenoid
- Anti-oxidant activity
- Anti-mutagenic activity
- Anti-tumor activity
- Anti-inflammatory activity
- Potent androgen receptor (AR) inhibitor
- Can be used for cancer research, especially prostate cancer of ADPC and CRPC phenotypes
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 50 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid. It exhibits weak antihepatotoxic and anti-inflammatory activities.
- Molecular weight: 822.93
- Formula: C42H62O16
- Appearance: Solid
- Color: White to off-white
- Structure classification: Ketones, aldehydes, acids
- Initial source: Plants, specifically Leguminosae, Glycyrrhiza glabra Linn.
- Purity: 99.79%
- In vitro solubility: DMSO: 100 mg/mL (121.52 mM; requires ultrasonic; hygroscopic DMSO significantly impacts solubility, use newly opened DMSO)
Selleck Chemical LLC Ursonic acid S3902-1g
Ursonic acid (Prunol Malol beta-Ursolic acid NSC4060 CCRIS 7123 TOS-BB-0966) present in many plants is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives such as experimental antitumor agents Ursonic acid induces the apoptosis of human cancer cells through multiple signaling pathways
Medchemexpress LLC Limonin | 1180-71-8 | 99.1% | 470.51 | 100 MG
Limonin (Standard) is an analytical standard of Limonin, intended for research and analytical applications. It exhibits inhibitory effects against HIV-1 with an EC50 of 60.0 μM and induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM. Limonin is recognized for its antiviral and antitumor activities. This product is commonly utilized in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS, serving as a reference standard supplied for assay purposes.
- Antiviral activity: Inhibits HIV-1.
- Antitumor activity: Induces apoptosis in human colon adenocarcinoma cells.
- Research grade: Intended for research and analytical applications.
- Analytical standard: Serves as a reference standard for assays.
- Versatile application: Commonly used in HPLC, GC, and MS research experiments.
Medchemexpress LLC Betulinic acid (standard) | 472-15-1 | MFCD00009619 | 99.2% | 456.70 | C30H48O3 | 50 MG
Betulinic acid (analytical standard) is a high-purity pentacyclic triterpenoid supplied for research and analytical applications. Supplied as a 50 mg solid with accompanying certificate of analysis and safety documentation, it is intended for use as a calibration standard and positive control in chromatographic and quantitative assays.
- High purity suitable for analytical use.
- Supplied as a solid 50 mg standard.
- Provided with COA and SDS for traceability.
- Suitable as a calibration standard or reference material.
- Applicable for chromatography, method development, and quantitative analysis.
Medchemexpress LLC Lupeol acetate | 1617-68-1 | MFCD00017362 | 98.0% | 468.75 g/mol | C32H52O2 | 10MG
Lupeol acetate is a triterpenoid acetate supplied as an analytical research standard for use in chemical and biological research. It serves as a reference material for analytical assays and research into anti-inflammatory, antibacterial, and anticancer activities. A certificate of analysis is provided for batch-specific storage and handling recommendations.
- CAS number 1617-68-1
- Chemical formula C32H52O2
- Molecular weight 468.75 g/mol
- Purity 98.0% (NMR)
- Intended for use as an analytical standard and reference material
- Certificate of analysis available for batch-specific storage and handling
Selleck Chemical LLC Betulinic acid S3603-10mg
Betulinic acid (ALS-357 Lupatic acid Betulic acid) a pentacyclic triterpenoid from Syzigium claviflorum is a inhibitor of HIV-1 with EC50 of 1 4 M It s reported that Betulinic acid acts as a new inhibitor of NF- B Phase 1/2
Medchemexpress LLC Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)- | 471-53-4 | 99.9% | 470.68 | 10 G
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
- Anti-ulcerative
- Anti-inflammatory
- Antiproliferative properties
eMolecules 67416-61-9 | (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid | MFCD03788777 | 10mg
Ambeed | (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid | 10mg | 524995179 | A106831 | 67416-61-9 | MFCD03788777 | 512.731 | C32H48O5
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Medchemexpress LLC Limonin | 1180-71-4 | >98% | 470.51 | 1 ML
Limonin is a natural product isolated from Dictamnus dasycarpus. It is known for its antiviral and antitumor activities, inhibiting HIV-1 and inducing apoptosis in human colon adenocarcinoma cells. In vitro studies show limonin's anti-proliferation effects on colon adenocarcinoma cells and pancreatic cancer cell lines, while in vivo research demonstrates its ability to significantly inhibit tumor growth in xenograft mouse models.
- Inhibits HIV-1 with an EC50 of 60.0 μM.
- Induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM.
- Shows anti-proliferation effects on Caco-2 and HCT-116 cells.
- Suppresses cell migration and invasion in HCT-116 cells.
- Activates Erk and p38 MAPK pathways.
- Significantly inhibits tumor growth in HCT-116 xenograft mouse models.