Acyl bromides
Aobchem 5-Benzoyl-2-thiophenecarbonitrile | 95% | CAS 79505-22-9 | C12H7NOS | 500mg
5-Benzoyl-2-thiophenecarbonitrile | 95% | CAS 79505-22-9 | C12H7NOS | 500mg
Aobchem 5-Benzoyl-2-thiophenecarbonitrile | 95% | CAS 79505-22-9 | C12H7NOS | 250mg
5-Benzoyl-2-thiophenecarbonitrile | 95% | CAS 79505-22-9 | C12H7NOS | 250mg
Medchemexpress LLC MitoB bromide | 1247025-84-8 | MFCD28976194 | 99.8% | 477.14 g·mol⁻¹ | C25H23BBrO2P | 5 MG
MitoB bromide is a mitochondria-targeted ratiometric probe used as an exomarker to detect mitochondrial hydrogen peroxide (H2O2) in living animals. It accumulates in mitochondria and is converted by H2O2 to a reaction product that allows quantification of mitochondrial oxidative stress by analytical methods such as mass spectrometry.
- Targeted detection of mitochondrial hydrogen peroxide in vivo.
- Enables ratiometric quantification via conversion to a measurable product.
- Compatible with mass spectrometry and analytical assays for in vivo studies.
- Provided in research-scale quantities with high purity for reproducible results.
Medchemexpress LLC Ipratropium bromide | 22254-24-6 | 1 ML
Ipratropium bromide is a muscarinic receptor antagonist, demonstrating IC50s of 2.9 nM for M1, 2 nM for M2, and 1.7 nM for M3 receptors. This compound effectively relaxes smooth muscle and is utilized in research focusing on conditions such as chronic obstructive pulmonary disease (COPD) and asthma.
- Targets mAChR
- Supports neurological disease and inflammation/immunology research
- Acts as a muscarinic receptor antagonist
- Exhibits IC50 values of 2.9 nM for M1, 2 nM for M2, and 1.7 nM for M3 receptors
- Relaxes smooth muscle
- Suitable for research on chronic obstructive pulmonary disease (COPD) and asthma
Medchemexpress LLC N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine | 67219-55-0 | 98.9% | 633.69 | 5 G
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine, also known as 5'-O-DMT-N4-Bz-dC, is a compound that can be used for the synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. It serves as a useful tool for probing enzyme-catalyzed cleavage processes in DNA.
- Used for synthesis of oligodeoxynucleotides.
- Useful tool for probing enzyme-catalyzed cleavage processes in DNA.
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 10mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC 1,3,5-tri-O-benzoyl-α-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 100 G
1,3,5-Tri-O-benzoyl-α-D-ribofuranose is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This product is intended for research use only and is not sold to patients.
- Targets nucleoside antimetabolite/analog pathways.
- Involved in cell cycle/DNA damage pathways.
- Soluble in DMSO at 100 mg/mL (216.24 mM), requiring ultrasonication.
- Powder is stable for 3 years at -20°C and 2 years at 4°C.
- In solvent, stable for 6 months at -80°C and 1 month at -20°C.
Medchemexpress LLC N4-Benzoyl-2 -O-meth 500mg
N4-Benzoyl-2 -O-methylcytidine is a natural cytidine nucleoside analog Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2]
Medchemexpress LLC (2e)-1-(3,4-dimethoxyphenyl)-5-fluoro-3-(4-fluorophenyl)-2-(2-fluorophenyl)pent-1-en-4-one bromide | 1390654-28-0 | >98.8% | 524.38 | 100 MG
KRN2 bromide is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6, without hindering high-salt-induced NFAT5 and its target gene expressions. KRN2 also dose-dependently inhibits NF-κB p65 binding to Nfat5 promoter 1 and directly blocks the interaction between NF-κB p65 and its DNA binding sequence in the upstream site of Nfat5 exon 1.
- Effectively suppresses AIA in which innate immune cells play a predominant role.
- Effectively suppresses CIA as well as AIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Medchemexpress LLC Azido-choline bromide | 2059973-54-3 | 99.6% | 239.11 g·mol⁻¹ | C6H15BrN4O | 1 ML
N3-Cho bromide (azido-choline bromide) is an azide-bearing choline analogue supplied as a ready-to-use 10 mM solution in DMSO for bioorthogonal labeling and click chemistry applications. It is intended for incorporation into membrane mimetics and for use in azide-alkyne cycloaddition workflows.
- Contains an azide functional group compatible with click chemistry reactions.
- Supplied as a 10 mM solution in DMSO, ready for dilution or reaction.
- High purity (listed at 99.63%), suitable for research use.
- Soluble in DMSO and water.
- Stable in solution when sealed at -80°C (up to 6 months) or -20°C (up to 1 month).
- Useful for membrane labeling and synthesis of phospholipid head-group analogues.
Medchemexpress LLC Cetrimonium bromide-d42 | 907216-28-8 | 99.8% | 406.71 | C19D42BrN | 10 MG
Deuterium-labeled cetrimonium bromide (d42) is a stable isotope-labeled form of the cationic surfactant cetrimonium bromide, supplied for research use as a tracer or internal standard. It is provided as a powder at high purity with defined storage conditions.
- Deuterium labeled (d42) tracer/internal standard.
- Purity 99.8%.
- Molecular formula C19D42BrN; molecular weight 406.71.
- CAS number 907216-28-8.
- Supplied as a powder in small pack sizes (5 mg, 10 mg, 25 mg; larger sizes by inquiry).
- Storage: powder -20°C (3 years); in solvent -80°C (6 months), -20°C (1 month).
Medchemexpress LLC QX-314 (bromide) | 24003-58-5 | MFCD00083182 | 96.6% | 343.30 | C16H27BrN2O | 1 ML
QX-314 bromide is a membrane-impermeable, permanently charged sodium channel blocker provided as a ready-to-use 10 mM solution in DMSO or as a solid for reconstitution. It is commonly used in electrophysiology and neurophysiology experiments to selectively block intracellular voltage-gated sodium channels during recordings and manipulations.
- Membrane-impermeable quaternary lidocaine derivative.
- Available as 10 mM solution in DMSO or solid for reconstitution.
- Used to block intracellular voltage-gated sodium channels in electrophysiology.
- CAS number 24003-58-5 for unambiguous identification.
- Supplied with reported purity suitable for research applications.
Medchemexpress LLC Bromoacetyl-PEG3-DBCO | 00-00-0 | 98.6% | 600.50 | C29H34BrN3O6 | 5 MG
Bromoacetyl-PEG3-DBCO is a heterobifunctional PEG-based linker for bioconjugation and PROTAC synthesis. It combines a DBCO bioorthogonal handle with a bromoacetyl electrophile and a short PEG3 spacer to enable efficient, selective conjugation and good solubility in small-scale synthetic workflows.
- Contains a DBCO moiety for strain-promoted alkyne-azide cycloaddition (SPAAC).
- Provides a bromoacetyl reactive handle for selective conjugation to thiols.
- PEG3 spacer enhances solubility and flexibility in conjugates.
- High purity (~98.6%) suitable for synthetic applications.
- Oil appearance facilitates handling for small-scale synthesis.
- Recommended storage at -20°C in pure form for long-term stability.
- Available in milligram-scale quantities for research use.
Apexbio Technology LLC Tiotropium Bromide hydrate 139404-48-1 10mg
Tiotropium Bromide hydrate is a small-molecule antagonist targeting muscarinic acetylcholine receptors (mAChRs) It is designed to competitively inhibit mAChRs thereby modulating airway smooth muscle contraction and mediating bronchodilation Tiotropium Bromide hydrate exerts its biological activity primarily through competitive antagonism at mAChRs resulting in relaxation of airway smooth muscle Based on these pharmacological properties Tiotropium Bromide hydrate holds research potential in respiratory pharmacology particularly for investigating mechanistic pathways in chronic obstructive pulmonary disease (COPD) receptor-ligand interactions and pulmonary pharmacodynamics associated with airway obstruction