Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

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5,326 – 5,340 of 5,862 results

5,326

Medchemexpress LLC Cephalexin hydrochloride | 59695-59-9 | 99.8% | 100 MG

Cephalexin hydrochloride is a potent, orally active, semisynthetic cephalosporin antibiotic. It demonstrates a broad antibacterial spectrum against various gram-positive and gram-negative bacteria by targeting penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. It is utilized in research for conditions such as pneumonia, strep throat, and bacterial endocarditis.

Potent, orally active, semisynthetic cephalosporin antibiotic
Broad antibacterial spectrum against gram-positive and gram-negative bacteria
Inhibits bacterial cell wall assembly by targeting penicillin-binding proteins
Disrupts polymer peptidoglycan biogenesis at 10 μg/mL
Exhibits antibacterial activity in animal models
Used in research for pneumonia, strep throat, and bacterial endocarditis

Pricing & Availability

5,327

Medchemexpress LLC Paroxetine hydrochloride hemihydrate | 110429-35-1 | 100.0% | 100 MG

Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an antidepressant, and has GRK2 inhibitory ability with an IC50 of 14 μM. This product is intended for research use only.

GRK2 inhibition with an IC50 of 14 μM.
Restrains T cell migration induced by CX3CL1.
Inhibits GRK2-induced activation of ERK and reduces pro-inflammatory cytokines in LPS-stimulated BV2 cells.
Attenuates symptoms of CIA rats and prevents histological joint damage.
Reduces myocyte cross-sectional area and ROS formation.
Decreases susceptibility to ventricular tachycardia and LV remodeling.
Attenuates tactile hypersensitivity in CCI models.

Pricing & Availability

5,328

Medchemexpress LLC BI-9787 | 3043939-18-7 | 99.5% | 489.58 | 5 MG

BI-9787 is a zwitterionic inhibitor for ketohexokinase (KHK), demonstrating IC50 values of 12 nM for hKHK-A and 12.8 nM for hKHK-C. It shows good metabolic stability in rat hepatocytes and favorable pharmacokinetic characteristics in rats. This product was designed by Boehringer Ingelheim and is available free of charge through their open innovation portal opnMe.com, alongside its negative control. It is intended for research use only and not for sale to patients.

Zwitterionic inhibitor for ketohexokinase (KHK)
IC50 of 12 nM for hKHK-A and 12.8 nM for hKHK-C
Exhibits good metabolic stability in rat hepatocyte
Shows good pharmacokinetic characteristics in rats
Intended for research use only

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5,329

Medchemexpress LLC Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride (1:1), (2S)- | 4136-37-2 | 179.64 | 1 G

Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride (1:1), (2S)- | 4136-37-2 | 179.64 | 1 G

Pricing & Availability

5,330

Medchemexpress LLC Stachydrine hydrochloride | 4136-37-2 | 179.64 | 500 MG

Stachydrine hydrochloride is the major active constituent of *Leonurus artemisia*, a potential therapy for cardiovascular diseases. It can inhibit the NF-κB signal pathway, exhibiting anti-hypertrophic activities.

Major active constituent of *Leonurus artemisia*
Potential therapy for cardiovascular diseases
Inhibits the NF-κB signal pathway
Exhibits anti-hypertrophic activities
Suppresses p-IκB (ser32) protein in cytosol
Suppresses NF-κB (p65) protein in nucleus
Inhibits MCF-7 and T47D cell proliferation in a dose- and time-dependent manner
Increases frequency of MCF-7 and T47D cells at G1 phase of cell cycle, suggesting cell cycle arrest

Pricing & Availability

5,331

eMolecules 717843-45-3 | 3-Bromo-4-methylpicolinonitrile | ChemScene | MFCD12761209 | 197.035 | C7H5BrN2 | 98.000 | Cc1ccnc(C#N)c1Br | 250mg | 632291282

3-Bromo-4-methylpicolinonitrile | ChemScene | 717843-45-3 | MFCD12761209 | 197.035 | C7H5BrN2 | 98.000 | Cc1ccnc(C#N)c1Br | 250mg | 632291282

Pricing & Availability

5,332

Medchemexpress LLC Arecaidine hydrochloride | 6018-28-6 | 1 ML

Arecaidine hydrochloride is a pyridine alkaloid. It functions as a potent GABA uptake inhibitor and acts as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1), competitively inhibiting L-proline uptake.

Pyridine alkaloid
Potent GABA uptake inhibitor
Functions as a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1)
Competitively inhibits L-proline uptake
Molecular formula: C7H12ClNO2
Derived from plants, specifically Palmae Areca catechu L.

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5,333

eMolecules 358-23-6 | Trifluoromethanesulfonic anhydride | Oakwood Chemical | MFCD00000408 | 282.130 | C2F6O5S2 | 99.000 | FC(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F | 100g | 537668379

Trifluoromethanesulfonic anhydride | Oakwood Chemical | 358-23-6 | MFCD00000408 | 282.130 | C2F6O5S2 | 99.000 | FC(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F | 100g | 537668379

Pricing & Availability

5,334

eMolecules 1112-67-0 | Tetrabutylammonium chloride | Ambeed | MFCD00011635 | 277.920 | C16H36ClN | 95.000 | [Cl-].CCCC[N+](CCCC)(CCCC)CCCC | 100g | 588341239

Tetrabutylammonium chloride | Ambeed | 1112-67-0 | MFCD00011635 | 277.920 | C16H36ClN | 95.000 | [Cl-].CCCC[N+](CCCC)(CCCC)CCCC | 100g | 588341239

Pricing & Availability

5,335

eMolecules 6313-33-3 | Formamidine Hydrochloride | Accela ChemBio (ASD) | MFCD00012865 | 80.520 | CH5ClN2 | 97.000 | Cl.NC=N | 25g | 510406957

Formamidine Hydrochloride | Accela ChemBio (ASD) | 6313-33-3 | MFCD00012865 | 80.520 | CH5ClN2 | 97.000 | Cl.NC=N | 25g | 510406957

Pricing & Availability

5,336

Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 25 MG

BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma.

Highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2).
IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively.
Potential for the treatment of poorly controlled asthma.
Solid appearance, white to off-white color.

Pricing & Availability

5,337

Medchemexpress LLC Ilginatinib hydrochloride | 1239358-85-0 | 98.9% | 425.89 | 25 MG

Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor. It demonstrates significant selectivity for JAK2 over JAK1, JAK3, and Tyk2. This compound is intended for research use only.

Highly active and orally bioavailable JAK2 inhibitor.
Exhibits selectivity for JAK2 over JAK1, JAK3, and Tyk2.
Potently prolongs survival and reduces splenomegaly in mouse models of myeloproliferative neoplasms.
Suppresses colony-forming unit-granulocyte/macrophage (CFU-GM) formation from myelodysplastic syndrome (MDS)-derived bone marrow mononuclear cells.

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5,338

Medchemexpress LLC Mk-571 sodium | 115103-85-0 | 99.8% | 537.07 | 25 MG

Mk-571 sodium | 115103-85-0 | 99.8% | 537.07 | 25 MG

Pricing & Availability

5,339

Medchemexpress LLC Bi-0115 | 4929-23-1 | 99.7% | 287.74 | 25 MG

BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 μM) that blocks cellular uptake of oxLDL. Its binding triggers receptor inhibition by forming dimers of the homodimeric ligand binding domain.

Selective inhibitor of LOX-1.
Blocks cellular uptake of oxLDL.
Binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain.
Efficiently reduces oxLDL internalization in the cellular context with IC50 values (5.4 μM) in good agreement with determined Kd values in SPR (4.3 μM) and ITC (6.99 μM).

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5,340

Medchemexpress LLC Aceclidine hydrochloride | 6109-70-2 | MFCD00468105 | 98.0% | 205.68 | 1 G

Aceclidine (Quinuclidin-3-yl acetate) hydrochloride is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). It is also a cycloplegic agent, a surfactant, a tonicity adjustor, and optionally a viscosity enhancer and an antioxidant. It has potential for research into various disorders including refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia.

Modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM)
Cycloplegic agent
Surfactant
Tonicity adjustor
Optionally a viscosity enhancer and an antioxidant
Potential for research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia

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Naphthalenes

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Medchemexpress LLC Cephalexin hydrochloride | 59695-59-9 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Paroxetine hydrochloride hemihydrate | 110429-35-1 | 100.0% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BI-9787 | 3043939-18-7 | 99.5% | 489.58 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride (1:1), (2S)- | 4136-37-2 | 179.64 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Stachydrine hydrochloride | 4136-37-2 | 179.64 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Arecaidine hydrochloride | 6018-28-6 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]- | 1093108-50-9 | 99.4% | 501.50 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ilginatinib hydrochloride | 1239358-85-0 | 98.9% | 425.89 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mk-571 sodium | 115103-85-0 | 99.8% | 537.07 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bi-0115 | 4929-23-1 | 99.7% | 287.74 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Aceclidine hydrochloride | 6109-70-2 | MFCD00468105 | 98.0% | 205.68 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More