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Filtered Search Results
Cambridge Isotope Laboratories 1 2 3 4-TCDD Instrument Performance Check (unlabeled/13C12 99%) in nonane 0 1 mL
1 2 3 4-TCDD Instrument Performance Check (unlabeled/13C12 99%) in nonane 0 1 mL
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Aobchem 1-(4-(Naphthalen-1-yl)phenyl)ethanol | 95% | C18H16O | 1g
1-(4-(Naphthalen-1-yl)phenyl)ethanol | 95% | C18H16O | 1g
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Aobchem AOBCHEM
5001079788 4- BENZYLOXY NAPHTHALEN-1-OL 2
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Medchemexpress LLC Thiobis-β-galactose-propyne | 1989627-40-8 | 98.0% | C27H40O12S2 | 10MG
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Thiobis-β-galactose-propyne is a thiobis-linked galactose derivative used as a multivalent galectin inhibitor in preclinical research. It is supplied as a solid and intended for biochemical and cell-based studies investigating galectin-mediated interactions.
- Multivalent galectin inhibitor suitable for biochemical assays.
- Contains a propyne functional group for click-chemistry conjugation.
- Reported high purity appropriate for in vitro applications.
- Supplied as a solid and stable under recommended frozen storage.
- Available in small mass vials convenient for screening and conjugation work.
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Medchemexpress LLC (6S)-Tetrahydrofolic acid | 71963-69-4 | C19H23N7O6 | 50 MG
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(6S)-Tetrahydrofolic acid is an endogenous metabolite that is significantly more active than its (6R) form. It promotes the binding of fluorodeoxyuridylate to thymidylate synthase and acts as a growth factor for P. cerevisiae. This compound also exhibits a low affinity and high dissociation rate for folate-binding protein.
- Significantly more active than (6R) form
- Promotes binding of fluorodeoxyuridylate to thymidylate synthase
- Acts as a growth factor for P. cerevisiae
- Exhibits low affinity and high dissociation rate for folate-binding protein
- Endogenous metabolite with a molecular weight of 445.43
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Medchemexpress LLC 3-Isoquinolinamine, N-[2-[(3S,4R)-3-fluoro-4-methoxy-1-piperidinyl]-4-pyrimidinyl]-5-(1-met | 2660250-10-0 | 99.4% | C28H37FN6O3S | 50 MG
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BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation. This product is used for the research of lung cancer, including non-small cell lung cancer (NSCLC).
- Potent and highly selective EGFR tyrosine kinase inhibitor
- Reversible and orally active
- Inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation
- Used for research of lung cancer, including non-small cell lung cancer
- Shows inhibitory activity against EGFRm/T790M double and EGFRm/T790M/C797S triple mutants
- Demonstrates robust EGFR pathway inhibition and anti-tumor activity in triple-mutant Osimertinib-resistant models
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Medchemexpress LLC 2-(naphthalen-2-yl)acetonitrile | 7498-57-9 | MFCD00004122 | 100.0% | 167.21 g·mol⁻¹ | C12H9N | 10 G
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2-(Naphthalen-2-yl)acetonitrile is an organic intermediate used in medicinal chemistry for the synthesis of various active compounds. It is provided for research use only and is not intended for human therapeutic use.
- used as a drug intermediate in organic synthesis.
- high purity suitable for research (reported 99.96%).
- chemical formula C12H9N and molecular weight 167.21 g·mol⁻¹.
- available in laboratory-scale pack sizes, including 10 g.
- supplied with safety and datasheet documentation for handling.
- stable solid; store in a cool, dry place as indicated in the SDS.
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Medchemexpress LLC Naphthol AS-BI | 1237-75-8 | 99.86% | 250 MG
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Naphthol AS-BI is a substrate of β-glucuronidase and produces a bright red effect after staining biological tissues. It is intended for research use only.
- Substrate for β-glucuronidase
- Produces bright red effect
- Suitable for staining biological tissues
- For research use only
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Medchemexpress LLC Benfluorex (hydrochloride) | 23642-66-2 | 99.6% | 1 G
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Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator. This compound is for research use only and activates insulin promoter activity.
- Increases GFP-positive cells
- Increases endogenous insulin mRNA
- Stimulates HNF4α expression
- Alters HNF4α protease sensitivity
- Decreases synthesis of acid-soluble products and ketone bodies from oleate
- Increases 14CO2 production into the citric acid cycle
- Inhibits gluconeogenesis from lactate/pyruvate
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Medchemexpress LLC Pramocaine hydrochloride | 637-58-1 | 99.7% | 1 ML
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Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. It is for research use only and not sold to patients.
- Molecular weight: 329.86
- Chemical formula: C17H28ClNO3
- Appearance: solid
- Color: white to off-white
- Purity: 99.74%
- CAS number: 637-58-1
- Shipping: room temperature in continental US
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC Amiselimod hydrochloride | 942398-84-7 | 98.7% | 413.90 | 100 MG
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Amiselimod hydrochloride is converted to its active metabolite Amiselimod phosphate by sphingosine kinases in vivo. It is an orally active and highly selective sphingosine 1-phosphate receptor-1 (S1P1) agonist. This compound is designed to reduce the bradycardia effects associated with fingolimod and other S1P receptor modulators. Amiselimod hydrochloride inhibits chronic colitis by preventing the infiltration of colitogenic Th1 and Th17 cells into the colon and inhibits lupus nephritis by reducing the infiltration of autoreactive T cells into the kidneys. It shows promise for the research of autoimmune diseases.
- Orally active and highly selective sphingosine 1-phosphate receptor-1 (S1P1) agonist.
- Designed to reduce bradycardia effects compared to other S1P receptor modulators.
- Inhibits chronic colitis.
- Inhibits lupus nephritis.
- Promising for research of autoimmune diseases.
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Medchemexpress LLC BI-9787 | 3043939-18-7 | 99.5% | 489.58 | 100 MG
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BI-9787 is a zwitterionic inhibitor for ketohexokinase, with an IC50 of 12 nM for hKHK-A and 12.8 nM for hKHK-C. It shows good metabolic stability in rat hepatocytes and good pharmacokinetic characteristics in rats. The compound was designed by Boehringer Ingelheim and is available through the opnMe.com open innovation portal, along with its negative control. It is intended for research use only and not for sale to patients.
- Purity: 99.46%
- CAS number: 3043939-18-7
- Molecular weight: 489.58
- Formula: C24H29F2N5O2S
- Appearance: Solid
- Color: White to off-white
- IC50 and target: 12 nM (hKHK-A); 12.8 nM (hKHK-C)
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Medchemexpress LLC Lofexidine hydrochloride | 21498-08-8 | 99.7% | 1 ML
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Lofexidine hydrochloride is a selective α2-receptor agonist, commonly used in research to alleviate the physical symptoms of opioid withdrawal. It is intended for research use only.
- Selective α2-receptor agonist
- Alleviates physical symptoms of opioid withdrawal
- For research use only
- Stable under recommended storage conditions
- Solid appearance
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Medchemexpress LLC 2-Butene-1,4-diamine, N1, N4-bis[3-(ethylamino)propyl]-, hydrochloride (1:4), (2Z)- | 206991-64-2 | 95.0% | 402.27 | 25 MG
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PG-11047 (CGC-11047) is a polyamine analogue used for the research of breast cancer. It offers the following features and benefits:
- Inhibits the growth of breast cell lines, with basal-like cell lines being inhibited at lower concentrations than luminal cell lines.
- Causes a significant decrease in S phase fraction at doses that produce little apoptosis.
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Selleck Chemical LLC VitaMin U S4811-25mg
Vitamin U (Methylmethioninesulfonium Chloride Cabagin-U Smethylmethionine) is a vitamin found in green vegetables It is used in the treatment of peptic ulcers colitis and gastritis and has an effect on secretory acid-forming and enzymatic functions of the intestinal tract
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