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Naphthalenes

Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.

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1

eMolecules​ Advanced ChemBlocks BIs(13-bis(26-diisopropylphenyl)imidazol-2-ylidene)copper(I) tetrafluoroborate 5g 798818822 X195391 97.000 886061-48-9 [null] 927.550 C54H72BCuF4N4

Advanced ChemBlocks BIs(13-bis(26-diisopropylphenyl)imidazol-2-ylidene)copper(I) tetrafluoroborate 5g 798818822 X195391 97.000 886061-48-9 [null] 927.550 C54H72BCuF4N4

ENCOMPASS_PREFERRED
2

Medchemexpress LLC CRA-026440 hydrochloride | 847459-98-7 | 98.1% | 456.92 | 100 MG
SDP

CRA-026440 hydrochloride is a potent, broad-spectrum HDAC inhibitor. It shows antitumor and antiangiogenic activities. This compound is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • Potent, broad-spectrum HDAC inhibitor
  • Shows antitumor and antiangiogenic activities
  • Click chemistry reagent
  • Contains an alkyne group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)

ENCOMPASS_PREFERRED
3

Medchemexpress LLC SBI-581 | 98.2% | 383.44 | 1 ML
SDP

SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor with an IC50 of 42 nM. It promotes TKS5α accumulation at RAB11-positive vesicles, inhibits invadopodia formation, and shows reasonable pharmacokinetics and antitumor activity in mice. It is also a click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc).

  • Promotes TKS5α accumulation at RAB11-positive vesicles
  • Inhibits invadopodia formation
  • Shows reasonable pharmacokinetics and antitumor activity in mice
  • Functions as a click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Displays moderate selectivity against a broad panel of kinases

ENCOMPASS_PREFERRED
4

Medchemexpress LLC CRA-026440 hydrochloride | 847459-98-7 | 98.1% | 456.92 | 1 ML
SDP

CRA-026440 hydrochloride is a potent, broad-spectrum Histone Deacetylase (HDAC) inhibitor. It exhibits antitumor and antiangiogenic activities. This compound also functions as a click chemistry reagent, containing an alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.

  • Potent, broad-spectrum HDAC inhibitor
  • Exhibits antitumor and antiangiogenic activities
  • Functions as a click chemistry reagent
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
  • Shows antiproliferative effect on HUVEC endothelial cells
  • Inhibits tumor cell growth and induces apoptosis
  • Inhibits ex vivo angiogenesis
  • Reduces tumor growth in xenograft models

ENCOMPASS_PREFERRED
5

Medchemexpress LLC SBI-581 | 98.2% | 383.44 | 25 MG
SDP

SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor with an IC50 of 42 nM. It promotes TKS5α accumulation at RAB11-positive vesicles and inhibits invadopodia formation. The compound demonstrates reasonable pharmacokinetics in mice and shows antitumor activity. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • Orally active and potent selective serine-threonine kinase TAO3 inhibitor
  • Promotes TKS5α accumulation at RAB11-positive vesicles
  • Inhibits invadopodia formation
  • Demonstrates reasonable pharmacokinetics in mice
  • Shows antitumor activity
  • Click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition
  • Moderate selectivity against a broad panel of kinases

ENCOMPASS_PREFERRED
6

Medchemexpress LLC Ald-Ph-amido-C2-PEG3-azide | 1807540-88-0 | 25 MG
SDP

Ald-Ph-amido-C2-PEG3-azide is a laboratory chemical used for the manufacture of substances and is for research use only. It is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This click chemistry reagent contains an azide group, enabling copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.

  • Used in the synthesis of PROTACs.
  • Functions as a PEG-based PROTAC linker.
  • Contains an azide group for click chemistry reactions.
  • Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc).
  • Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
  • Exploits the intracellular ubiquitin-proteasome system to degrade target proteins.
  • For research use only.

ENCOMPASS_PREFERRED
7

Medchemexpress LLC Ald-Ph-amido-C2-PEG3-azide | 1807540-88-0 | 98.9% | 50 MG
SDP

Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent.

  • Contains an azide group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
  • Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups

ENCOMPASS_PREFERRED
8

Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | MFCD00150062 | 99.2% | 262.73 | 25 MG
SDP

Neocuproine hydrochloride monohydrate can be used to prepare complex solutions for studying antioxidant capacity determination in biological samples based on copper reduction complexes.

  • Appearance: solid
  • Color: off-white to light yellow
  • Handling instructions: store at room temperature, keep dry and cool. In solvent: -80°C 1 year, -20°C 6 months.

ENCOMPASS_PREFERRED
9

Medchemexpress LLC Neocuproine hydrochloride monohydrate | 303136-82-5 | 99.15% | 262.73 | 100 MG
SDP

Neocuproine hydrochloride monohydrate can be used to prepare complex solutions for studying antioxidant capacity determination in biological samples based on copper reduction complexes.

  • Used for research purposes only
  • High purity: 99.15%
  • Available in solid appearance
  • Color: Off-white to light yellow
  • Soluble in DMSO
  • Store at room temperature, keep dry and cool

ENCOMPASS_PREFERRED
10

Medchemexpress LLC BI-847325 | 1207293-36-4 | 98.15% | 464.56 | 50 MG
SDP

BI-847325 is an ATP competitive dual inhibitor of MEK and aurora kinases (AK). It inhibits the growth and survival of both treatment-naive and drug-resistant melanoma cell lines, decreasing the expression of MEK and Mcl-1 while increasing the expression of pro-apoptotic protein Bim. This compound is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • ATP competitive dual inhibitor of MEK and aurora kinases
  • Inhibits MEK2 with an IC50 of 4 nM
  • Inhibits aurora kinases with IC50 values of 15 nM for AK-C and 25 nM for AK-A
  • Inhibits LCK (5 nM) and MAP3K8 (93 nM) at 1,000 nM
  • Induces apoptosis in treatment-naive and drug-resistant xenografted melanoma in vivo
  • Click chemistry reagent with an Alkyne group

ENCOMPASS_PREFERRED