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Filtered Search Results
Medchemexpress LLC SN-011 | 2249435-90-1 | C25H19FN2O4S | 10MG
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This small-molecule STING inhibitor blocks STING activation by competing with cyclic dinucleotides for the STING binding pocket, reducing downstream interferon signaling. It is reported to inhibit mouse and human STING with an IC50 of 76 nM and is intended for research into STING-driven immune signaling, inflammation, and autoimmunity.
- Potent STING antagonist with reported IC50 of 76 nM.
- Active against mouse and human STING.
- Competitive inhibitor of cyclic dinucleotide binding.
- Provided with analytical data including COA, H NMR, RP-HPLC, and MS.
- Suitable for cell-based and biochemical studies of innate immune signaling.
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Medchemexpress LLC HY-111102 5mg Medchemexpress, FL-411 CAS:2118944-88-8 Purity:>98%
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Medchemexpress, HY-111102 5mg FL-411 CAS:2118944-88-8 FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4(1). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-113972 5mg Medchemexpress, Methyl mycophenolate CAS:31858-66-9 Purity:>98%
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Medchemexpress, HY-113972 5mg Methyl mycophenolate CAS:31858-66-9 Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Rutin | 153-18-4 | MFCD00006830 | 1g
Oakwood Chemicals | Rutin | 1g | 480150585 | 099508 | | 153-18-4 | MFCD00006830 | 610.521 | C27H30O16
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eMolecules 24502-78-1 | Medchem Express | Acetylshikonin | 5mg | 559839911 | HY-N2181 | MFCD00143538 | 330.336 | C18H18O6
Medchem Express | CP-640186 (hydrochloride) | 5mg | 446265299 | HY-15259A | 591778-70-0 | MFCD28167776 | 522.090 | C30H36ClN3O3
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eMolecules 611-24-5 | 2-(METHYLAMINO)PHENOL | AstaTech | MFCD00462180 | 123.155 | C7H9NO | 95.000 | CNc1ccccc1O | 5g | 323603056
2-(METHYLAMINO)PHENOL | AstaTech | 611-24-5 | MFCD00462180 | 123.155 | C7H9NO | 95.000 | CNc1ccccc1O | 5g | 323603056
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Medchemexpress LLC Rki-1447 dihydrochloride | 1782109-09-4 | 99.9% | 399.29 | 10 MG
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RKI-1447 dihydrochloride is a potent and selective ROCK inhibitor, effectively suppressing colorectal carcinoma cell growth and promoting apoptosis. It functions by inhibiting ROCK1 (IC50 14.5 nM) and ROCK2 (IC50 6.2 nM), without affecting AKT, MEK, and S6 kinase phosphorylation. This compound has demonstrated significant anticancer activity in both in vitro and in vivo studies, including the inhibition of mammary tumor growth and antitumor effects in colorectal carcinoma.
- Potent and selective ROCK inhibitor
- Suppresses colorectal carcinoma cell growth
- Promotes apoptosis in a dose-dependent manner
- Inhibits phosphorylation of ROCK substrates MLC-2 and MYPT-1
- Exhibits anticancer activity in colorectal carcinoma (CRC)
- Inhibits mammary tumor growth in transgenic mice
- Shows antitumor activity in CRC without physiological toxicity
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eMolecules 79558-09-1 | Medchem Express | L-165041 | 5mg | 446270728 | HY-20019 | MFCD04974501 | 402.443 | C22H26O7
Medchem Express | L-165041 | 5mg | 446270728 | HY-20019 | 79558-09-1 | MFCD04974501 | 402.443 | C22H26O7
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Medchemexpress LLC Vilanterol trifenatate | 503070-58-4 | MFCD 21362970 | 99.3% | 774.77 g/mol | C44H49Cl2NO7 | 5 MG
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Vilanterol trifenatate is a long-acting β2-adrenergic receptor agonist supplied as a research reagent. It produces sustained activation of airway β2 receptors to increase cAMP and relax bronchial smooth muscle, and is provided as a high-purity solid for preclinical and pharmacological studies.
- Long-acting β2-adrenergic receptor agonist suitable for airway pharmacology studies.
- High reported purity (LCMS 99.3%).
- White to off-white solid, convenient for formulation and analytical work.
- Useful as a reference compound in receptor pharmacology and preclinical respiratory research.
- For research use only; not for human or clinical applications.
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Sigma Aldrich Fine Chemicals Biosciences Phenol 991KG
PHENOL Phenol 991KG
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eMolecules 31677-74-4 | 2-(6-Benzyloxyindolyl)ethylamine Hemisulfate | Toronto Research Chemicals630.760 | C34H38N4O6SOS(O)(=O)=O.NCCc1c[nH]c2cc(OCc3ccccc3)ccc12.NCCc1c[nH]c2cc(OCc3ccccc3)ccc12 | 100mg | 483383598
2-(6-Benzyloxyindolyl)ethylamine Hemisulfate | Toronto Research Chemicals | 31677-74-4630.760 | C34H38N4O6SOS(O)(=O)=O.NCCc1c[nH]c2cc(OCc3ccccc3)ccc12.NCCc1c[nH]c2cc(OCc3ccccc3)ccc12 | 100mg | 483383598
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Medchemexpress LLC HY-N0374 5mg Medchemexpress, Licochalcone C CAS:144506-14-9 Purity:>98%
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Medchemexpress, HY-N0374 5mg Licochalcone C CAS:144506-14-9 Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13458 5mg Medchemexpress, Droxidopa CAS:23651-95-8 Purity:>98%
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Medchemexpress, HY-13458 5mg Droxidopa CAS:23651-95-8 Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Peldesine dihydrochloride | 2772702-10-8 | MFCD32878297 | 99.3% | 314.17 g/mol | C12H13Cl2N5O | 10 MG
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Peldesine dihydrochloride is the dihydrochloride salt of a potent purine nucleoside phosphorylase (PNP) inhibitor used in preclinical biochemical and pharmacological research. It exhibits low-nanomolar PNP inhibition across species and suppresses T-cell proliferation, supporting studies in T-cell lymphoma, psoriasis, and HIV-related immunology.
- Potent PNP inhibition with low-nanomolar IC50s for human, rat, and mouse.
- Inhibits T-cell proliferation (IC50 ~800 nM), useful for immunology studies.
- High purity (~99.3%) suitable for research applications.
- Molecular weight 314.17 g/mol and solid, white to off-white appearance.
- Available in small research pack sizes and as DMSO solution formats for assays.
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Medchemexpress LLC Tyrphostin AG-825 | 149092-50-2 | MFCD01074971 | 98.0% | 397.47 g·mol⁻¹ | C19H15N3O3S2 | 10 MG
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AG-825 (Tyrphostin AG-825) is a selective, ATP-competitive ErbB2 (HER2) tyrosine kinase inhibitor used in cellular and biochemical research to probe ErbB2 signaling and cell proliferation. It exhibits anticancer and anti-inflammatory activity and has been shown to accelerate apoptosis in human neutrophils.
- Selective ErbB2 inhibitor with reported IC50 of 0.35 μM.
- Additional activity against EGFR with IC50 ~19 μM.
- High purity suitable for research, reported at 98.02%.
- Molecular weight 397.47 g·mol⁻¹; formula C19H15N3O3S2.
- Soluble in DMSO (recommended 250 mg/mL with ultrasonic assistance) and formulatable for in vivo use.
- Available in small research pack sizes and larger quantities for expanded studies.
- Stable as powder and in solvent when stored under the recommended conditions.
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