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Filtered Search Results
Pfaltz & Bauer INDENE OXIDE, 768-22-9, MFCD00046870
INDENE OXIDE, 768-22-9, MFCD00046870
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Medchemexpress LLC N,N,N',N'-Tetracyclohexyl-3-oxapentanediamide (Calcium ionophore II) | 74267-27-9 | 99.4% | 460.69 | 100 MG
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N,N,N',N'-Tetracyclohexyl-3-oxapentanediamide, also known as Calcium ionophore II, is a lipophilic ionophore. It is commonly used in preparing calcium ion-selective electrodes due to its ability to facilitate the transport of calcium ions across membranes. This chemical has a high purity of 99.36% and a molecular weight of 460.69.
- High purity for accurate research
- Functions as a lipophilic ionophore
- Essential for creating calcium ion-selective electrodes
- Facilitates efficient calcium ion transport
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Medchemexpress LLC FMF-04-159-R | 2741262-15-5 | 99.8% | 685.02 | 5 MG
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FMF-04-159-R is a cyclin-dependent kinase CDK14 and CDK16 inhibitor with IC50 values of 5.9 and 139.1 nM. This compound is suitable for research applications.
- Acts as a CDK14 and CDK16 inhibitor.
- Demonstrates potent inhibitory activity with low nanomolar IC50 values.
- Ideal for research purposes.
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Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 100 MG
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ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. ETC-159 blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. It is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.
- Potent, orally available PORCN inhibitor.
- Inhibits β-catenin reporter activity with an IC50 of 2.9 nM.
- Blocks the secretion and activity of all Wnts.
- Exhibits robust activity in various cancer models driven by high Wnt signaling.
- Highly efficacious in colorectal cancers (CRCs) with R-spondin translocations.
- Inhibits mouse PORCN with an IC50 of 18.1 nM.
- Demonstrates good oral pharmacokinetics in mice with 100% oral bioavailability after a single oral dose of 5 mg/kg.
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Selleck Chemical LLC ETC-159
ETC-159 (ETC-1922159) is an orally available potent porcupine inhibitor with an IC50 of 2 9 nM for inhibiting -catenin reporter activity in STF3A cells
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Medchemexpress LLC β-Carotene | 7235-40-7 | 536.87 | 1 G
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β-Carotene (Provitamin A) is a naturally-occurring vitamin A precursor and a carotenoid compound. It modulates reactive oxygen species (ROS) and exhibits both antioxidant and anti-inflammatory activities, functioning as either an antioxidant or a prooxidant depending on the biological environment. β-Carotene also demonstrates anticancer activities by inducing apoptosis in breast cancer cells.
- Naturally-occurring vitamin A precursor.
- Modulates reactive oxygen species (ROS).
- Possesses antioxidant and anti-inflammatory activities.
- Acts as an antioxidant or prooxidant.
- Induces apoptosis in breast cancer cells.
- Exhibits anticancer properties.
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Selleck Chemical LLC Lycopene S3943-5mg
Lycopene ( -Carotene) is a linear unsaturated hydrocarbon carotenoid the major red pigment in fruits such as tomatoes pink grapefruit apricots red oranges watermelon rosehips and guava It is a natural antioxidant Lycopene ( -Carotene) is a linear unsaturated hydrocarbon carotenoid the major red pigment in fruits such as tomatoes pink grapefruit apricots red oranges watermelon rosehips and guava It is a natural antioxidant
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Medchemexpress LLC β-Carotene-13C10 | 301150-50-5 | 546.80 | 1 MG
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β-Carotene-13C10 is a 13C-labeled version of β-Carotene, a naturally occurring vitamin A precursor and carotenoid. It modulates reactive oxygen species, demonstrating both antioxidant and anti-inflammatory properties, and can induce apoptosis in breast cancer cells.
- 13C-labeled compound
- Acts as a vitamin A precursor
- Modulates reactive oxygen species
- Exhibits antioxidant and anti-inflammatory activities
- Can function as an antioxidant or prooxidant
- Induces apoptosis in breast cancer cells
- Useful as a tracer
- Can be used as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
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Selleck Chemical LLC ETC-159
ETC-159 (ETC-1922159) is an orally available potent porcupine inhibitor with an IC50 of 2 9 nM for inhibiting -catenin reporter activity in STF3A cells
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Medchemexpress LLC N-(1-((3-(4-(dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1 | 2741262-15-5 | 98.8% | 685.02 g/mol | C28H32Cl3N7O5S | 10 MG
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Small-molecule inhibitor of cyclin-dependent kinases CDK14 and CDK16 for biochemical and cell-based research. It demonstrates potent inhibition with reported IC50 values of 5.9 nM (CDK14) and 139.1 nM (CDK16). The compound is supplied as a purified solid suitable for laboratory use.
- Potent inhibition of CDK14 and CDK16 with reported IC50s of 5.9 nM and 139.1 nM.
- High purity (98.8% by HPLC).
- Well-characterized physicochemical properties, molecular weight 685.02 g/mol.
- Supplied as a solid suitable for low-temperature storage.
- Available in milligram quantities for research use (10 MG).
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Sigma Aldrich Fine Chemicals Biosciences Lycopene 98 HPLC from toma10MG
Lycopene is a carotenoid found in many red fruits and vegetables such as watermelon pink guava and tomato. Lycopene is a potent antioxidant. It is suggested that lycopene is used by the plant to protect against reactive oxygen species (ROS).
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Medchemexpress LLC β-Carotene | 7235-40-7 | 536.87 | 25 G
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β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. It may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. It induces breast cancer cells apoptosis, with anticancer activities.
- Up-regulates PPAR-γ expression and ROS production in MCF-7 cancer cells.
- Decreases the survival of MCF-7 cells in a dose-dependent manner.
- Enhances the expression levels of PPAR-γ mRNA and protein in a time-dependent manner.
- Down-regulates the COX-2 but up-regulates the p21 mRNA level and protein expression.
- Increases the percentage of early apoptosis.
- Induces cytochrome C release.
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Medchemexpress LLC β-Carotene (standard) | 7235-40-7 | 536.87 | 100 MG
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β-Carotene (Standard) is the analytical standard of β-Carotene. This product is intended for research and analytical applications. β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative research experiments in HPLC, GC and MS.
- It is commonly used in quantitative research experiments in HPLC, GC and MS.
- It is commonly used in methodological research experiments in HPLC, GC and MS.
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Indofine Chemical Lycopene, 5 Mg
LYCOPENE 5 MG, Herbal Standards, C40H56, MW: 536.88, >98% by UV, 502-65-8, MFCD00017350
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Aobchem AOBCHEM
5001078936 4-TRICYCLO 3.3.1.13 7 DEC-1-YL
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