Organic phosphoric acids and derivatives
Apexbio Technology LLC TAK-632 1228591-30-7 10mM (in 1mL DMSO)
TAK-632 (CAS 1228591-30-7) is a selective inhibitor of RAF kinase isoforms including BRAF CRAF and the mutant BRAF-V600E exhibiting IC50 values of 8 3 nM 1 4 nM and 2 4 nM respectively By targeting the RAF family of serine/threonine kinases TAK-632 disrupts the RAS-RAF-MEK-ERK signaling pathway implicated in MAPK cascade regulation In cellular assays TAK-632 promotes BRAF-CRAF dimerization and demonstrates potent antiproliferative effects in A375 and SK-MEL-2 melanoma cell lines with GI50 values of 6 nM and 11 nM respectively In vivo oral administration in SK-MEL-2 xenograft models inhibits ERK phosphorylation and tumor growth without notable toxicity TAK-632 is suitable for investigating RAF-driven signaling and drug resistance in oncogenic pathway studies
Chem-Impex International, Inc. Dibenzyl phosphate | 1623-08-1 | MFCD00004775 | 5G
Dibenzyl phosphate, 1623-08-1, MFCD00004775, 5G
TARGETMOL CHEMICALS INC sn-Glycerol 3-phosphate 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.sn-Glycerol 3-phosphate, produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway. Purity 98.41%
Medchemexpress LLC Riboflavin phosphate sodium | 130-40-5 | 93.4% | 500 MG
Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2), which is an essential nutrient for animals. It is utilized in research for progressive keratoconus, corneal ectasia, and irregular astigmatism. Riboflavine phosphate sodium is also described as a highly effective NAD+-recycling agent.
- Derivative of Riboflavin (vitamin B2)
- Essential nutrient for animals
- Utilized in research for progressive keratoconus, corneal ectasia, and irregular astigmatism
- Highly effective NAD+-recycling agent
Sigma Aldrich Fine Chemicals Biosciences Sodium phosphate monobasic5KG
Sodium phosphate monobasic5KG
Medchemexpress LLC Trimethyl phosphate | 512-56-1 | 98.0% | C3H9O4P | 1 G
Trimethyl phosphate is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It is for research use only.
- Used as a biochemical reagent
- Suitable for life science-related research
- Not sold to patients
Alkali Scientific 4 Nitrophenyl Phosphate bis Cyclohexylammonium Salt, 1 G
Nitrophenyl Phosphate bis Cyclohexylammonium Salt, 1g is a reagent commonly used in biochemical applications, especially in enzyme assays and molecular biology experiments. This compound is a versatile substrate for phosphatases and other enzymes that hydrolyze phosphoric esters. The cyclohexylammonium salt form helps improve solubility in various solvents, making it suitable for use in diverse reaction systems. It is used to detect phosphatase activity in biological samples and can be applied in studies involving enzyme kinetics, protein assays, and diagnostic procedures. The reagent is available in a 1g format, making it convenient for laboratory-scale applications.
Medchemexpress LLC Sodium phosphate dibasic dodecahydrate | 10039-32-4 | MFCD00149181 | 98.0% | 10g
Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive Phosphoric acid disodium dodecahydrate promotes gel formation improves food texture and thermal properties of materials Phosphoric acid disodium dodecahydrate induces glomerular calcification Phosphoric acid disodium dodecahydrate can be used in kidney disease research[1][2][3]
Medchemexpress LLC ODN 2216 | 332437-00-0 | DNA, d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G) | 100 MG
ODN 2216 is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. It induces high amounts of IFN-α and IFN-β, and also stimulates IFN-α by plasmacytoid DC and IL-12 (p40) production by dendritic cells. This compound can stimulate IFN-γ production in peripheral blood mononuclear cells indirectly via IFN-α/β, activate NK cells, and promote IFN-γ production of TCR-triggered CD4+ T cells.
- Induces high amounts of IFN-α and IFN-β
- Stimulates IFN-γ production in peripheral blood mononuclear cells
- Activates NK cells and promotes IFN-γ production of TCR-triggered CD4+ T cells
- Drives Th1 development of naive CD4 T cells
- Significantly decreases apoptosis of thymic DC
- Induces T-cell mediated antitumor immune response in murine vaccination models
Medchemexpress LLC Diethyl decanedioate | 110-40-7 | 99.8% | 258.36 | 25 G
Diethyl decanedioate is an organic compound commonly used as a raw material for flavors and food additives. It can be used to make fruit and mint flavors, and is widely used in some food processing and cosmetic production. Additionally, this compound serves as a reagent and intermediate in some organic synthesis reactions. As a biochemical reagent, it can be utilized as a biological material or organic compound for life science-related research.
- Used as a raw material for flavors and food additives (fruit and mint flavors)
- Widely used in food processing and cosmetic production
- Functions as a reagent and intermediate in organic synthesis reactions
- Biochemical reagent for life science-related research
Medchemexpress LLC Phosphoric acid, calcium salt (2:3) | 7758-87-4 | 98.0% | 10 G
Tricalcium phosphate is a biological material or organic compound widely used in life science research.
- Used in life science research.
- Product has not been fully validated for medical applications.
- For research use only.
- Available as a white to off-white solid.
- Purity of 98.0%.
Medchemexpress LLC Dibenzyl L-glutamate tosylate | 2791-84-6 | 98.4% | 499.58 | 50 G
Dibenzyl L-glutamate tosylate is a glutamic acid derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements and are recognized as beneficial ergogenic dietary substances. They can:
- Influence the secretion of anabolic hormones
- Supply fuel during exercise
- Improve mental performance during stress-related tasks
- Prevent exercise-induced muscle damage
Alkali Scientific 4 Nitrophenyl Phosphate (Disodium Salt, Hexahydrate), 1 Kg
Nitrophenyl Phosphate (Disodium Salt, Hexahydrate) is a chromogenic reagent used for detecting alkaline phosphatase activity in various biological and biochemical assays. The 1kg pack is designed for high-volume laboratories requiring significant quantities of this substrate for enzyme activity measurements. When hydrolyzed by alkaline phosphatase, this compound produces a color change, providing a visual indicator of enzyme activity. This reagent is widely used in clinical diagnostics, microbiological testing, and pharmaceutical research. It is particularly useful for enzyme assays, protein quantification, and enzyme kinetics studies, providing consistent and reproducible results in laboratory settings.
Apexbio Technology LLC Histamine Phosphate 51-74-1 10mM (in 1mL H2O)
Histamine Phosphate (51-74-1) is a small-molecule agonist targeting histamine receptors specifically the H1 and H2 receptors It is designed to activate these receptors thereby regulating vascular function and cellular signaling pathways Histamine Phosphate exerts its biological activity primarily through receptor-mediated signaling leading to vasodilation in arteries and capillaries In in vitro assays Histamine Phosphate demonstrates receptor activation with reported IC50 values for H1 and H2 receptors typically ranging from nanomolar to micromolar concentrations in receptor binding studies Based on these pharmacological properties Histamine Phosphate holds research potential in investigating vascular permeability inflammation gastric acid secretion and in characterizing histamine receptor signaling mechanisms
Apexbio Technology LLC Diethyl Acetamidomalonate 1068-90-2 500g
Diethyl Acetamidomalonate (1068-90-2) is an organic compound containing both amide and ester functional groups It is primarily utilized in chemical synthesis for producing amino acid derivatives and other biologically active molecules Diethyl Acetamidomalonate enables the introduction of acetylamino groups into target compounds via synthetic transformations such as nucleophilic substitution Based on these properties Diethyl Acetamidomalonate holds research potential in the development of novel amino acid analogues and bioactive small-molecule compounds supporting studies in medicinal chemistry and pharmaceutical development