Vinylogous acids
Cromolyn sodium salt, 98%
CAS: 15826-37-6 Molecular Formula: C23H14Na2O11 Molecular Weight (g/mol): 512.33 MDL Number: MFCD00057744 InChI Key: VLARUOGDXDTHEH-UHFFFAOYSA-L Synonym: cromolyn sodium,sodium cromoglycate,disodium cromoglycate,sodium cromoglicate,sodium cromolyn,gastrocrom,nasalcrom,cromoglycate disodium,natrium cromoglicat,lomudal PubChem CID: 27503 ChEBI: CHEBI:128458 SMILES: [Na+].[Na+].OC(COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O)COC1=C2C(=O)C=C(OC2=CC=C1)C([O-])=O
Hypoxanthine, 99.5%
CAS: 68-94-0 Molecular Formula: C5H4N4O Molecular Weight (g/mol): 136.11 MDL Number: MFCD00005725 InChI Key: FDGQSTZJBFJUBT-UHFFFAOYSA-N Synonym: hypoxanthine,6-hydroxypurine,9h-purin-6-ol,sarkin,6-oxopurine,sarcine,sarkine,3h-purin-6-ol,7h-purin-6-ol,purin-6 1h-one PubChem CID: 790 ChEBI: CHEBI:17368 SMILES: O=C1N=CNC2=C1NC=N2
Sigma Aldrich Fine Chemicals Biosciences Hypoxanthine powder, BioReagent, suitable for cell culture | 68-94-0 | MFCD00005725 | 5G
Hypoxanthine powder, BioReagent, suitable for cell culture | Purity: >=99% | Mol Wt: 136.11 | 68-94-0 | MFCD00005725 | 5G
Medchemexpress LLC HY-18407 100mg Medchemexpress, N-Methylisatoic anhydride CAS:10328-92-4 Purity:>98%
Medchemexpress, HY-P7198 10ug I-309/CCL1 (CHO-expressed), Human CAS: Recombinant Human I-309/CCL1 (CHO-expressed) attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 4-chloro-1-piperidin-4-yl-N-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyrazole-3-carboxamide | 1817698-21-7 | MFCD28386213 | >98.0% | 371.8 g/mol | C17H18ClN7O | 50MG
BDP5290 is a small-molecule kinase inhibitor selective for Rho-associated kinases (ROCK) and myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK). It is used as a research reagent in biochemical and cell-based assays to probe pathways controlling myosin light chain phosphorylation, cell motility, and tumor cell invasion.
- Potent inhibition of ROCK1 (IC50 5 nM), ROCK2 (IC50 50 nM), MRCKα (IC50 10 nM), and MRCKβ (IC50 100 nM).
- High reported purity: >98.0%.
- Molecular formula C17H18ClN7O and molecular weight 371.8 g/mol.
- Suitable for in vitro and cell-based research applications investigating cytoskeletal regulation.
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | MFCD09878272 | 99.9% | 399.48 | C23H29NO5 | 5 MG
Tesmilifene fumarate is a research-grade small molecule that acts as an H1C (histamine) receptor antagonist. It is reported to potentiate a wide range of cytotoxic agents and may offer some protection to normal cells. The compound is supplied for laboratory research and analytical applications.
- Acts as an H1C receptor antagonist.
- Potentiates a wide range of cytotoxic agents.
- May offer some protection to normal cells.
- Molecular formula C23H29NO5 and molecular weight 399.48.
- Purity typically 99.85%.
- Available in small research quantities, including 5 MG packs.
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | MFCD09878272 | 99.9% | 399.48 g/mol | C23H29NO5 | 25 MG
Tesmilifene fumarate (DPPE fumarate) is an H1C receptor antagonist used as a research reagent to potentiate a broad range of cytotoxic agents and may offer some protection to normal cells. It is supplied as a white to off-white solid and as a DMSO solution for laboratory use.
- Potentiates a wide range of cytotoxic agents.
- May provide partial protection to normal cells during cytotoxic exposure.
- High reported purity (99.85%).
- Molecular weight 399.48 g/mol; formula C23H29NO5.
- Available as solid packs and as a 10 mM solution in DMSO.
- Recommended storage: powder at -20 °C or 4 °C; in solvent at -80 °C or -20 °C.
Medchemexpress LLC Sparfosic acid | 51321-79-0 | 99.3% | 255.12 g/mol | C6H10NO8P | 5 MG
Sparfosic acid is N-phosphonacetyl-L-aspartic acid, a DNA antimetabolite and potent inhibitor of aspartate transcarbamoyl transferase (ATCase). It is used in biochemical and cell-based research to disrupt de novo pyrimidine biosynthesis and has been reported to increase the cytotoxic effect of 5-fluorouracil combined with interferon-alpha in cancer cell models.
- Inhibits aspartate transcarbamoyl transferase (ATCase).
- Acts as a DNA antimetabolite affecting pyrimidine biosynthesis.
- Reported to enhance cytotoxicity of 5-fluorouracil plus interferon-alpha.
- High purity (99.3%) suitable for biochemical studies.
- Available in small research pack sizes (1 mg-100 mg).
- Molecular formula C6H10NO8P; molecular weight 255.12 g/mol.
Medchemexpress LLC Polyporenic acid C | 465-18-9 | 5 MG
Polyporenic acid C is a lanostane-type triterpenoid isolated from Poria cocos. This compound induces apoptosis and exhibits anticancer activity, particularly against non-small cell lung cancer, by affecting various cellular pathways.
- Induces the cleavage of caspase-8 and caspase-3
- Causes the cleavage of PARP
- Reduces the phosphorylation level of Akt (Ser473)
- Increases the phosphorylation of PTEN and p53 (Ser15)
- Activates JNK
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | 99.9% | 399.48 g/mol | C23H29NO5 | 10 MG
Tesmilifene fumarate is the fumarate salt of tesmilifene (DPPE fumarate), a small-molecule H1C receptor antagonist reported to potentiate a wide range of cytotoxic chemotherapies while offering some protection to normal cells. It is supplied for research use in solid and ready-to-use solution formats.
- Potentiates cytotoxic chemotherapy in research settings.
- Acts as an H1C receptor antagonist.
- High purity (≈99.9%).
- Molecular weight 399.48 g/mol; formula C23H29NO5.
- Available in multiple vial sizes and as a 10 mM solution in DMSO.
- Intended for research use and stored at -20°C.
Medchemexpress LLC Ensitrelvir fumarate | 2757470-18-9 | 100.0% | 647.95 g/mol | C26H21ClF3N9O6 | 5 MG
Ensitrelvir fumarate is the fumarate salt of an orally active, non-covalent, non-peptidic inhibitor of the SARS-CoV-2 3CL (main) protease. It is supplied as a high-purity solid for research use in antiviral, enzymatic, and mechanism-of-action studies.
- Potent 3CL protease inhibition (IC50 13 nM).
- Provided as the fumarate salt for improved handling and stability.
- High purity appropriate for biochemical and cell-based assays.
- Solid, white to off-white form for accurate weighing and formulation.
- Small research pack sizes suitable for assay development and screening.
Medchemexpress LLC Revumenib | 2169919-21-3 | 99.99% | 630.82 | 50 MG
Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell-based IC50 of 10-20 nM. It can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
- Potent and specific Menin-MLL inhibitor
- Applicable for research into MLL-rearranged acute leukemias (ALL and AML)
- Shows in vivo plasma IC50 of 53 nM
- Provides significant survival benefit and leukemic control in aggressive MOLM-13 disseminated xenografts in vivo
Medchemexpress LLC Cotadutide acetate | 99.3% | 3728.04 | 5 MG
Cotadutide acetate is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR, with EC50 values of 6.9 pM and 10.2 pM respectively. It is utilized in research for obesity and type 2 diabetes (T2D) due to its ability to facilitate weight loss, improve glycaemic control, and alleviate fibrosis.
- Potent dual agonist of GLP-1 and GCGR.
- Facilitates weight loss and glycaemic control.
- Alleviates fibrosis.
- Used in research for obesity and type 2 diabetes (T2D).
- Stimulates cAMP accumulation in β-cell lines and hepatocytes.
- Potentiates glucose-stimulated insulin secretion.
- Induces mitochondrial turnover and enhances mitochondrial function.
- Suppresses food intake.
- Reduces body weight.
- Reduces hepatic fibrosis and inflammation.