Azobenzenes

Medchemexpress LLC Iclepertin | 1421936-85-7 | MFCD34474019 | 100.0% | C20H18F6N2O5S | 10MG

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Iclepertin is a potent, selective, orally active glycine transporter 1 (GlyT1) inhibitor provided for research use. The compound elevates extracellular glycine and has been investigated for cognitive impairment in neurological disorders; it is intended only for laboratory research and not for human administration.

• Potent, selective glycine transporter 1 (GlyT1) inhibitor.
• Orally active; relevant for in vivo and in vitro studies.
• High chemical purity (99.97%).
• Used in preclinical research on cognitive impairment and schizophrenia.
• Available in small lab-scale pack sizes suitable for experimental workflows.

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Medchemexpress LLC Mitoguazone 10mg | 459-86-9 | 10MG

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Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis Mitoguazone induces cell apoptosis Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages Mitoguazone has the potential for acute leukemia Hodgkin s and non-Hodgkin s lymphoma treatment[1 [2 [3 [4

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eMolecules​ Medchem Express / Orismilast / 5mg / 719836725 / HY-117960 / / 1353546-86-7 / [null] / 510.290 / C19H15Cl2F2NO7S

Medchem Express / Orismilast / 5mg / 719836725 / HY-117960 / / 1353546-86-7 / [null] / 510.290 / C19H15Cl2F2NO7S

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Medchemexpress LLC 4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 9,10-dihydro-3,5-dihydroxy-2-(4-methoxyphenyl)-8,8-dimethyl | 38226-86-7 | 368.38 | 5 MG

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β-Anhydroicaritin is isolated from Boswellia carterii Birdware and possesses important biological and pharmacological effects. It ameliorates the degradation of periodontal tissue, inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats, and decreases the overproduction of NO, IL-10, TNF-α, MCP-1, and IL-6 in peritonitis mice. Additionally, it inhibits the elevation of intracellular Ca2+ and markedly decreases iNOS protein expression.

• Antiosteoporosis properties
• Estrogen regulation properties
• Antitumor properties
• Ameliorates the degradation of periodontal tissue
• Inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats
• Decreases the overproduction of NO, IL-10, TNF-α, MCP-1, and IL-6 in peritonitis mice
• Inhibits the elevation of intracellular Ca2+
• Markedly decreases iNOS protein expression

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eMolecules​ Medchem Express / Tolinapant / 5mg / 446259580 / HY-109565 / / 1799328-86-1 / [null] / 539.696 / C30H42FN5O3

Medchem Express / Tolinapant / 5mg / 446259580 / HY-109565 / / 1799328-86-1 / [null] / 539.696 / C30H42FN5O3

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eMolecules​ AstaTech / 15-DIHYDROXYPENTAN-3-ONE / 0.25g / 297085484 / 20750 / 95.000 / 4254-85-7 / MFCD06658431 / 118.132 / C5H10O3

AstaTech / 15-DIHYDROXYPENTAN-3-ONE / 0.25g / 297085484 / 20750 / 95.000 / 4254-85-7 / MFCD06658431 / 118.132 / C5H10O3

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Medchemexpress LLC GPX4-IN-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 100 MG

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GPX4-IN-3 is a potent and selective glutathione peroxidase 4 (GPX4) inhibitor and a selective ferroptosis inducer. It demonstrates significant inhibition of GPX4 and effectively induces ferroptosis in various cell lines, showing a strong ability to increase lipid peroxides. This compound also exhibits antitumor activity and good biological safety in preclinical models, effectively suppressing tumor growth.

• Potent glutathione peroxidase 4 (GPX4) inhibitor
• Selective ferroptosis inducer
• Increases lipid peroxide levels
• Induces ferroptosis with satisfactory selectivity
• Increases reactive oxygen species (ROS) levels in 4T1 cells
• Exhibits antitumor activity
• Good biological safety in vivo
• Suppresses tumor growth in mouse xenograft models

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Medchemexpress LLC ELN318463 | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 5 MG

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ELN318463 is a selective γ-secretase inhibitor that targets amyloid precursor protein (APP). It exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase, showing significantly higher selectivity for PS1. This compound behaves as a classic γ-secretase inhibitor and has been shown to reduce brain Aβ levels in models of Alzheimer's disease.

• Highly selective inhibition of PS1 γ-secretase.
• Demonstrates potent inhibition of Aβ production in cells.
• Shows reduced brain Aβ levels in animal models.
• Possesses characteristics of a classic γ-secretase inhibitor.
• Off-white to light yellow solid appearance.
• Soluble in DMSO.
• Available in various quantities.
• Stable under recommended storage conditions.

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Medchemexpress LLC Beta-anhydroicaritin | 38226-86-7 | 99.7% | 368.38 g/mol | C21H20O6 | 10 MG

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β-Anhydroicaritin is a prenylflavonoid natural product provided for laboratory research use. It is reported to exhibit biological activities such as anti-osteoporosis, estrogenic modulation, and anti-tumor effects, and is supplied as a small-scale research reagent suitable for biochemical and cellular studies.

• Prenylflavonoid natural product.
• Reported activities include anti-osteoporosis, estrogenic modulation, and anti-tumor effects.
• CAS number 38226-86-7 and molecular formula C21H20O6.
• High purity (99.7%).
• Available as a 10 mg research vial for biochemical assays.

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eMolecules​ Ambeed / (2S4R)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid / 25g / 490492901 / A109231 / / 13504-85-3 / [null] / 265.265 / C13H15NO5

Ambeed / (2S4R)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid / 25g / 490492901 / A109231 / / 13504-85-3 / [null] / 265.265 / C13H15NO5

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eMolecules​ Ambeed / 23-Dimethoxyterephthalaldehyde / 100mg / 599119640 / A532477 / / 179693-85-7 / MFCD18072900 / 194.186 / C10H10O4

Ambeed / 23-Dimethoxyterephthalaldehyde / 100mg / 599119640 / A532477 / / 179693-85-7 / MFCD18072900 / 194.186 / C10H10O4

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eMolecules​ Ambeed / Methyl 4H-thieno[32-b]pyrrole-5-carboxylate / 100mg / 490503631 / A128471 / / 82782-85-2 / MFCD06797484 / 181.210 / C8H7NO2S

Ambeed / Methyl 4H-thieno[32-b]pyrrole-5-carboxylate / 100mg / 490503631 / A128471 / / 82782-85-2 / MFCD06797484 / 181.210 / C8H7NO2S

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eMolecules​ ChemScene / 36-Dibromopicolinaldehyde / 100mg / 714110566 / CS-0146972 / 0.000 / 1215183-85-9 / MFCD16250664 / 264.904 / C6H3Br2NO

ChemScene / 36-Dibromopicolinaldehyde / 100mg / 714110566 / CS-0146972 / 0.000 / 1215183-85-9 / MFCD16250664 / 264.904 / C6H3Br2NO

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Medchemexpress LLC Cdc7-IN-5 (compound I-B) | 1402057-86-6 | 96.7% | C25H23N3O5 | 10MG

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Cdc7-IN-5 is a small-molecule inhibitor of the CDC7 serine-threonine kinase used in research on DNA replication and cell cycle regulation. The compound is provided as a dry solid with molecular formula C25H23N3O5, molecular weight 445.47, and reported purity around 96.7%.

• Inhibits CDC7 kinase activity in biochemical and cellular assays.
• Useful for studies of DNA replication and cell cycle control.
• Supplied as a dry solid with high reported purity for research use.
• Soluble in DMSO for preparation of concentrated stock solutions.
• Available in research-scale quantities, including 10 mg and sample sizes.

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Medchemexpress LLC WR99210 50mg | 47326-86-3 | 394.7 g/mol | C14H18Cl3N5O2 | 50 MG

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WR99210 is a potent dihydrofolate reductase (DHFR) inhibitor used in antiparasitic research and as a selection reagent for Plasmodium transfection. It is supplied as a research-grade free base and is used in laboratory studies that require selective inhibition of parasite DHFR.

• Potent dihydrofolate reductase (DHFR) inhibition with subnanomolar activity.
• Commonly used as a selection reagent for Plasmodium transfection experiments.
• Provided as the free base form suitable for research applications.
• Typical pack size: 50 mg.
• For research use only; not for human or clinical use.

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