Azobenzenes
Medchemexpress LLC Cadrofloxacin 100mg | 153808-85-6 | 100 MG
Cadrofloxacin is an orally active fluoroquinolone antibiotic research chemical with activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria. It is supplied as a powder for laboratory research and analytical applications.
- High purity: 98.2%.
- Molecular weight: 411.38 g/mol.
- Chemical formula: C19H20F3N3O4.
- CAS number: 153808-85-6.
- Supplied as a powder, stable at -20°C for long-term storage.
- Available in 100 MG quantity for research use.
eMolecules 185259-85-2 | Medchem Express | GR-46611 | 5mg | 724441955 | HY-101248 | MFCD00953517 | 377.488 | C23H27N3O2
Medchem Express | PARP10|15-IN-3 | 5mg | 761041080 | HY-146502 | 2892064-88-7 | 274.320 | C15H18N2O3
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eMolecules 1799328-86-1 | Medchem Express | Tolinapant | 5mg | 446259580 | HY-109565 | 539.696 | C30H42FN5O3
Medchem Express | SAG (dihydrochloride) | 1mg | 536984039 | HY-12848C | 2702366-44-5 | 562.980 | C28H30Cl3N3OS
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eMolecules 648927-86-0 | Medchem Express | Firibastat | 5mg | 599150364 | HY-109058 | MFCD20921962 | 368.5 | C8H20N2O6S4
Medchem Express | Firibastat | 5mg | 599150364 | HY-109058 | 648927-86-0 | MFCD20921962 | 368.500 | C8H20N2O6S4
Medchemexpress LLC Beta-anhydroicaritin | 38226-86-7 | 99.7% | 368.38 g/mol | C21H20O6 | 10 MG
β-Anhydroicaritin is a prenylflavonoid natural product provided for laboratory research use. It is reported to exhibit biological activities such as anti-osteoporosis, estrogenic modulation, and anti-tumor effects, and is supplied as a small-scale research reagent suitable for biochemical and cellular studies.
- Prenylflavonoid natural product.
- Reported activities include anti-osteoporosis, estrogenic modulation, and anti-tumor effects.
- CAS number 38226-86-7 and molecular formula C21H20O6.
- High purity (99.7%).
- Available as a 10 mg research vial for biochemical assays.
Chemscene ChemScene | 2-Amino-3-hydroxynitrobenzene | 500G | CS-W008642 | 0.98 | 603-85-0| MFCD00010875 | 154.13
ChemScene | 2-Amino-3-hydroxynitrobenzene | 500G | CS-W008642 | 0.98 | 603-85-0| MFCD00010875 | 154.13
Medchemexpress LLC Voacamine | 3371-85-5 | 5 MG
Voacamine is an indole alkaloid with cannabinoid 1 (CB1) antagonistic activity. It can inhibit nuclear translocation. Voacamine enhances the effect of Doxorubicin by interfering with P-glycoprotein (P-gp) function. It promotes apoptosis-independent autophagic cell death in human osteosarcoma cells. Voacamine activates the mitochondrial-associated apoptosis signaling pathway and inhibits the PI3K/Akt/mTOR signaling pathway to suppress breast cancer progression. Additionally, Voacamine inhibits EGFR to exert oncogenic activity against colorectal cancer.
- Indole alkaloid
- Acts as a cannabinoid 1 (CB1) antagonist
- Enhances Doxorubicin effect through P-gp interference
- Promotes autophagic cell death in osteosarcoma cells
- Suppresses breast cancer progression by inhibiting PI3K/Akt/mTOR signaling
- Exerts oncogenic activity against colorectal cancer by inhibiting EGFR
Medchemexpress LLC Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-aze | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 100 MG
ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor, demonstrating 51-fold selectivity for PS1 with EC50s of 12 nM for PS1 and 656 nM for PS2. It functions as a classic γ-secretase inhibitor, selectively inhibiting Aβ production over Notch signaling in cells. Oral administration *in vivo* leads to an acute reduction of brain Aβ in models of Alzheimer's disease.
- Amyloid precursor protein (APP) selective γ-secretase inhibitor
- Exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase
- Demonstrates 51-fold selectivity for PS1
- Selectively inhibits Aβ production over Notch signaling in cells
- Displaces an active site directed inhibitor *in vitro*
- Leads to acute reduction of brain Aβ *in vivo* in Alzheimer's disease models
Medchemexpress LLC Gpx4-in-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 50 MG
Gpx4-in-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 50 MG
Medchemexpress LLC ELN318463 | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 5 MG
ELN318463 is a selective γ-secretase inhibitor that targets amyloid precursor protein (APP). It exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase, showing significantly higher selectivity for PS1. This compound behaves as a classic γ-secretase inhibitor and has been shown to reduce brain Aβ levels in models of Alzheimer's disease.
- Highly selective inhibition of PS1 γ-secretase.
- Demonstrates potent inhibition of Aβ production in cells.
- Shows reduced brain Aβ levels in animal models.
- Possesses characteristics of a classic γ-secretase inhibitor.
- Off-white to light yellow solid appearance.
- Soluble in DMSO.
- Available in various quantities.
- Stable under recommended storage conditions.
Medchemexpress LLC Iclepertin | 1421936-85-7 | 512.42 | 50 MG
Iclepertin (BI-425809) is a potent, selective, and orally active glycine transporter 1 (GlyT1) inhibitor. It is inactive against GlyT2 and is used for research into Alzheimer's disease and schizophrenia. It inhibits GlyT1 in rat primary neurons and human SK-N-MC cells, and a single oral administration has shown to increase glycine CSF levels in rats.
- Potent, selective, and orally active glycine transporter 1 (GlyT1) inhibitor
- Inactive against GlyT2
- Used for Alzheimer's disease research
- Used for schizophrenia research
- Increases glycine cerebrospinal fluid (CSF) levels
Medchemexpress LLC Regaloside C | 117591-85-2 | 5 MG
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. It targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α, making it applicable to research related to inflammatory diseases.
- Acts as an anti-inflammatory agent.
- Acts as an antioxidant.
- Scavenges ABTS free radicals.
- Scavenges DPPH free radicals.
- Targets multiple molecules.
- Applicable to research related to inflammatory diseases.
