Azobenzenes

Medchemexpress LLC 5-chloro-2-fluoro-4-[(1S,2R)-2-(2-methylpyrazol-3-yl)cyclohexyl]oxy-N-pyrimidin-4-ylbenzenesulfonamide | 1450595-86-4 | Not found on authoritative sources | 99.6% | C20H21ClFN5O3S | 10MG

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DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor used in pain research. It shows low-nanomolar inhibition of human NaV1.7, activity in rodent models, and has demonstrated analgesic effects in preclinical studies.

• Potent NaV1.7 inhibition: hNaV1.7 IC50 = 22.8 nM; mNaV1.7 IC50 ≈ 59.4 nM.
• Orally active with reported analgesic effects in preclinical models.
• High purity, typically 99.6% by supplier specification.
• Defined chemical identity: CAS 1450595-86-4; formula C20H21ClFN5O3S; MW 465.93 g·mol⁻¹.
• Soluble in DMSO and compatible with common in vivo formulation vehicles.
• Stable as a solid with recommended refrigerated or frozen storage for long-term retention.

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Medchemexpress LLC GSK1702934A | 924377-85-5 | 99.11% | 395.52 | 10 MG

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GSK1702934A is a selective agonist for TRPC3, a transient receptor potential canonical channel. It plays a role in modulating cardiac contractility and arrhythmogenesis through the activation of TRPC3. In vitro studies have shown its ability to induce TRPC3/6-currents in HEK293 cells, with EC50 values of 0.08 mM for TRPC3 and 0.44 mM for TRPC6. It also induces transient, non-selective conductance and prolonged action potentials in TRPC3-overexpressing myocytes, and promotes NCX currents. In vivo, GSK1702934A has been observed to transiently increase blood pressure in conscious Sprague Dawley rats at doses ranging from 0.3-3 mg/kg.

• Acts as a selective agonist for TRPC3.
• Modulates cardiac contractility and arrhythmogenesis by activating TRPC3.
• Induces TRPC3/6-currents in HEK293 cells.
• Promotes NCX currents in TRPC3-overexpressing myocytes.
• Increases blood pressure in vivo in animal models.

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eMolecules​ 434936-85-3 | IMIDAZO[1,2-A]PYRAZIN-8-OL | AstaTech | MFCD11846490 | 135.126 | C6H5N3O | 95.000 | Oc1nccn2ccnc12 | 0.25g | 268500354

IMIDAZO[1,2-A]PYRAZIN-8-OL | AstaTech | 434936-85-3 | MFCD11846490 | 135.126 | C6H5N3O | 95.000 | Oc1nccn2ccnc12 | 0.25g | 268500354

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Medchemexpress LLC MIND4-19 | 129544-85-0 | 99.9% | 373.47 | 5 MG

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MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. This compound is intended for use in researching Huntington's disease.

• Solid, white to off-white appearance
• Soluble in DMSO for in vitro applications
• Can be dissolved using various co-solvents for in vivo protocols
• Targeted for SIRT2 inhibition

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Medchemexpress LLC Kansuinine A | 57701-86-7 | 99.81% | 730.75 | 10 MG

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Kansuinine A inhibits IL-6-induced Stat3 activation and exhibits antiviral and anticancer activities. It is for research use only. This compound is soluble in DMSO at concentrations ≥ 100 mg/mL.

• Possesses antiviral and anticancer activity
• Inhibits IL-6-induced Stat3 activation
• Shows a survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB (ED50 3.28 μg/mL) and TrkA (ED50 7.92 μg/mL)
• Available documentation includes: data sheet, COA, SDS, HNMR, RP-HPLC, MS, and handling instructions

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Medchemexpress LLC (R)-5,7-Dimethoxyflavanone | 1277188-85-8 | 5 MG

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(R)-5,7-Dimethoxyflavanone exhibits potent antimutagenic activity against MeIQ mutagenesis in Ames test utilizing S. typhimurium TA100 and TA98 strains. Additionally, it significantly and dose-dependently inhibits inflammatory mediators.

• Potent antimutagenic activity
• Inhibits inflammatory mediators
• Molecular weight of 284.31
• Chemical formula C17H16O4
• Appears as a white to off-white solid
• Classified as a flavonoid and flavanone
• Initially sourced from plants

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Medchemexpress LLC MIND4-19 | 129544-85-0 | 99.93% | 373.47 | 100 MG

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MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease.

• Potent SIRT2 inhibitor.
• IC50 value of 7.0 μM for SIRT2.
• Can be used for researching Huntington's disease.

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eMolecules​ 1661845-86-8 | Medchem Express | CRT0105950 | 5mg | 784543803 | HY-120025 | 393.89 | C21H16ClN3OS

ChemScene | 23-Dichloro-6-nitroquinoxaline | 1g | 569146224 | CS-0105603 | 2379-60-4 | MFCD00454905 | 244.030 | C8H3Cl2N3O2

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eMolecules​ 51334-85-1 | AstaTech | 4-(P-TOLYL)PHTHALAZIN-1(2H)-ONE | 0.25g | 696740265 | D74982 | 98 | MFCD00222976 | 236.274 | C15H12N2O

AstaTech | 4-(P-TOLYL)PHTHALAZIN-1(2H)-ONE | 0.25g | 696740265 | D74982 | 98.000 | 51334-85-1 | MFCD00222976 | 236.274 | C15H12N2O

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eMolecules​ 144231-85-6 | Medchem Express | Calpain-2-IN-1 | 5mg | 769193475 | HY-145155 | MFCD28400876 | 527.618 | C28H37N3O7

ChemScene | (S)-1-(26-Dimethoxyphenyl)ethan-1-amine hydrochloride | 100mg | 569145801 | CS-0101659 | 1956437-80-1 | MFCD24424960 | 217.690 | C10H16ClNO2

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Medchemexpress LLC Fluorofenidone | 848353-85-5 | 99.8% | 10MG

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Fluorofenidone | 848353-85-5 | 99.8% | 10MG

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Medchemexpress LLC Eln318463 | 851600-86-7 | 99.5% | 471.8 g/mol | C19H20BrClN2O3S | 10 MG

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This compound is an amyloid precursor protein (APP)-selective γ-secretase inhibitor for in vitro research. It preferentially inhibits PS1-containing γ-secretase (EC50 = 12 nM) over PS2 (EC50 = 656 nM), providing ~51-fold selectivity. The solid is high purity, soluble in DMSO, and intended for biochemical and cellular assay applications.

• High purity (99.5%).
• APP-selective γ-secretase inhibitory activity.
• Potent PS1 inhibition (EC50 12 nM), reduced PS2 activity.
• Soluble in DMSO for assay preparation.
• Suitable for biochemical and cellular assays.

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Medchemexpress LLC EPQpYEEIPIYL | 147612-86-0 | 99.5% | 1473.52 | 1 MG

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EPQpYEEIPIYL is a phosphopeptide that functions as a Src homology 2 (SH2) domain ligand. It activates members of the Src family, such as Lck, Hck, and Fyn, by binding to their SH2 domains. The phosphopeptide pY324, derived from hmT with the sequence EPQpYEEIPIYL, exhibits high-affinity binding to GST fusion proteins of the Lck SH2 domain and the Src SH2 domain. This product is used in cancer and cancer targeted therapy research, and is related to the protein tyrosine kinase/RTK pathway.

• Phosphopeptide and Src homology 2 (SH2) domain ligand
• Activates Src family members such as Lck, Hck, and Fyn
• High-affinity binding to GST fusion proteins of Lck SH2 domain and Src SH2 domain
• Soluble in H2O at 2 mg/mL (1.36 mM) with ultrasonic treatment and pH adjustment to 2 with HCl
• Used in cancer and cancer targeted therapy research
• Related to the protein tyrosine kinase/RTK pathway

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eMolecules​ 93913-86-1 | 3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid | J & W PharmLab LLC | MFCD08235220 | 206.245 | C11H14N2O2 | 96.000 | OC(=O)C1CCN(CC1)c1ccncc1 | 1g | 525323339

3,4,5,6-Tetrahydro-2H-[1,4']bipyridinyl-4-carboxylic acid | J & W PharmLab LLC | 93913-86-1 | MFCD08235220 | 206.245 | C11H14N2O2 | 96.000 | OC(=O)C1CCN(CC1)c1ccncc1 | 1g | 525323339

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Medchemexpress LLC Cadrofloxacin 50mg | 153808-85-6 | 411.38 g/mol | C19H20F3N3O4 | 50 MG

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Cadrofloxacin is a fluoroquinolone-class antibacterial compound for laboratory research. It is a small-molecule agent with formula C19H20F3N3O4 and a molecular weight of 411.38 g/mol, supplied at high purity for experimental and analytical use.

• Fluoroquinolone antibiotic for research applications.
• Molecular formula C19H20F3N3O4.
• Molecular weight 411.38 g/mol.
• Purity >98.2% (HPLC) as stated by supplier.
• Available in small pack sizes suitable for laboratory use, including 50 MG.
• Store and handle according to the supplied safety data sheet.

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