Azobenzenes
Medchemexpress LLC Rhodojaponin V | 37720-86-8 | 5 MG
Rhodojaponin V is a diterpenoid isolated from the leaves of *Rhododendron molle* and is recognized for its anti-inflammatory activity. It is the C-14 acetylation product of Rhodojaponen III, presented as a white to off-white solid. This high-purity compound (99.96%) is intended strictly for research purposes.
- Diterpenoid with anti-inflammatory activity
- C-14 acetylation product of Rhodojaponen III
- Appearance as a white to off-white solid
- High purity of 99.96%
- Suitable for research applications
Medchemexpress LLC GPX4-IN-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 100 MG
GPX4-IN-3 is a potent and selective glutathione peroxidase 4 (GPX4) inhibitor and a selective ferroptosis inducer. It demonstrates significant inhibition of GPX4 and effectively induces ferroptosis in various cell lines, showing a strong ability to increase lipid peroxides. This compound also exhibits antitumor activity and good biological safety in preclinical models, effectively suppressing tumor growth.
- Potent glutathione peroxidase 4 (GPX4) inhibitor
- Selective ferroptosis inducer
- Increases lipid peroxide levels
- Induces ferroptosis with satisfactory selectivity
- Increases reactive oxygen species (ROS) levels in 4T1 cells
- Exhibits antitumor activity
- Good biological safety in vivo
- Suppresses tumor growth in mouse xenograft models
Medchemexpress LLC Manool | 596-85-0 | 290.48 | 50 MG
Manool is a diterpene derived from Salvia officinalis. It selectively induces cytotoxicity in cancer cells and arrests them at the G(2)/M phase of the cell cycle. Manool has shown higher cytotoxic activity against HeLa (IC50=6.7 μg/mL) and U343 (IC50=6.7 μg/mL) cells. Additionally, it exhibits a protective effect against chromosome damage induced by MMS in HepG2 cells.
- Diterpene from Salvia officinalis.
- Induces selective cytotoxicity in cancer cells.
- Arrests cancer cells at the G(2)/M phase of the cell cycle.
- Exhibits protective effect against chromosome damage.
Medchemexpress LLC SU5205 | 3476-86-6 | 98.02% | 239.24 | 50 MG
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM. It inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM.
- Inhibitor of VEGFR2 (FLK-1)
- Inhibits ligand-induced endothelial mitogenesis for VEGF
Medchemexpress LLC Sudan III (Sudan Red III) | 85-86-9 | 98.2% | 500 MG
Sudan III is a hydrophobic bisazo dye. Its color changes from orange to blue when exposed to a small volume of sulfuric acid. The acetonitrile solution of Sudan III is most suitable for observing this color-change phenomenon. Studies using H-NMR and UV-Vis spectroscopy indicate that the color change mechanism is due to the protonation of the dye by sulfuric acid. This product is for research use only.
- Changes color from orange to blue when exposed to sulfuric acid.
- Acetonitrile solution is suitable for observing color change.
- Protonation of the dye by sulfuric acid causes the color change.
- For research use only.
eMolecules AstaTech / HALOPERIDOL / 1g / 696739973 / AT13670 / 95.000 / 52-86-8 / MFCD00051423 / 375.870 / C21H23ClFNO2
AstaTech / HALOPERIDOL / 1g / 696739973 / AT13670 / 95.000 / 52-86-8 / MFCD00051423 / 375.870 / C21H23ClFNO2
Medchemexpress LLC GSK1702934A | 924377-85-5 | 99.11% | 395.52 | 50 MG
GSK1702934A is a selective TRPC3 agonist that modulates cardiac contractility and arrhythmogenesis by activation of TRPC3.
- Selective TRPC3 agonist.
- Modulates cardiac contractility and arrhythmogenesis.
- Induces TRPC3/6-currents in HEK293 cells.
- Induces a transient, non-selective conductance and prolonged action potentials in TRPC3-overexpressing myocytes.
- Promotes NCX currents in TRPC3-overexpressing myocytes.
- Transiently increases blood pressure in conscious Sprague Dawley rats.
- Useful for research applications.
- Available for research use only.
eMolecules Ambeed / 2-(4-(Bromomethyl)phenyl)-4455-tetramethyl-132-dioxaborolane / 1g / 525123326 / A207813 / / 138500-85-3 / MFCD02179493 / 297.000 / C13H18BBrO2
Ambeed / 2-(4-(Bromomethyl)phenyl)-4455-tetramethyl-132-dioxaborolane / 1g / 525123326 / A207813 / / 138500-85-3 / MFCD02179493 / 297.000 / C13H18BBrO2
eMolecules ChemScene / 2-Cyclopropylpyridine-4-carbonitrile / 100mg / 569144638 / CS-0060776 / 0.000 / 1020747-85-6 / MFCD18089268 / 144.177 / C9H8N2
ChemScene / 2-Cyclopropylpyridine-4-carbonitrile / 100mg / 569144638 / CS-0060776 / 0.000 / 1020747-85-6 / MFCD18089268 / 144.177 / C9H8N2
Medchemexpress LLC SU5205 | 98.4% | 100 MG
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.
- No clinical development reported
eMolecules AstaTech / 2-(24-DIFLUOROPHENOXY)-5-NITROPYRIDINE / 0.25g / 437210136 / AB3643 / 95.000 / 219865-86-8 / MFCD00067766 / 252.177 / C11H6F2N2O3
AstaTech / 2-(24-DIFLUOROPHENOXY)-5-NITROPYRIDINE / 0.25g / 437210136 / AB3643 / 95.000 / 219865-86-8 / MFCD00067766 / 252.177 / C11H6F2N2O3
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 25 MG
C-021 is a small-molecule CCR4 antagonist supplied for research use. It inhibits CCR4-mediated chemotaxis in human and mouse cells and blocks CCL22-induced GTPγS binding, making it suitable for biochemical and cellular assays.
- Target: CCR4 (GPCR), suitable for immunology and GPCR research.
- Potent CCR4 antagonist with reported IC50s of 140 nM (human chemotaxis), 39 nM (mouse chemotaxis), and 18 nM in GTPγS binding assays.
- Molecular formula C27H41N5O2 and molecular weight 467.65 g/mol.
- Reported purity 99.95% and solid appearance (off-white to light yellow).
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or animal therapeutic use.
eMolecules ChemScene / 4-Nitropiperidine hydrochloride / 100mg / 603128780 / CS-0162514 / 0.000 / 1881295-85-7 / MFCD29043359 / 166.610 / C5H11ClN2O2
ChemScene / 4-Nitropiperidine hydrochloride / 100mg / 603128780 / CS-0162514 / 0.000 / 1881295-85-7 / MFCD29043359 / 166.610 / C5H11ClN2O2
Medchemexpress LLC 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | 274925-86-9 | MFCD09954136 | 99.9% | 273.24 | C14H11NO5 | 50 MG
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor provided as a solid research compound for in vitro and in vivo studies. It is used to study COMT-mediated metabolism of L-DOPA and related pharmacology, and is supplied with characterization data and storage recommendations for experimental stability.
- Reversible COMT inhibitor for research use.
- Reported purity 99.9%.
- Molecular weight 273.24 g/mol.
- Physical form solid powder.
- High solubility in DMSO (≥100 mg/mL) and formulated in vivo solubility ≥2.5 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline.
- Recommended storage 4°C protected from light; in solution store at -80°C up to 6 months or -20°C up to 1 month.
eMolecules AstaTech / (3-PHENOXYPHENYL)METHYLAMINE HCL / 1g / 112531058 / AR1547 / 95.000 / 376637-85-3 / MFCD07781045 / 235.710 / C13H14ClNO
AstaTech / (3-PHENOXYPHENYL)METHYLAMINE HCL / 1g / 112531058 / AR1547 / 95.000 / 376637-85-3 / MFCD07781045 / 235.710 / C13H14ClNO