Azobenzenes

eMolecules​ ChemScene / 1-(2-Isopropoxypyridin-3-yl)ethanone / 100mg / 582634293 / CS-0042760 / 0.000 / 1551553-85-5 / MFCD27974420 / 179.219 / C10H13NO2

ChemScene / 1-(2-Isopropoxypyridin-3-yl)ethanone / 100mg / 582634293 / CS-0042760 / 0.000 / 1551553-85-5 / MFCD27974420 / 179.219 / C10H13NO2

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eMolecules​ Medchem Express / FAK-IN-7 / 5mg / 761041122 / HY-148109 / / 19948-85-7 / [null] / 295.360 / C16H13N3OS

Medchem Express / FAK-IN-7 / 5mg / 761041122 / HY-148109 / / 19948-85-7 / [null] / 295.360 / C16H13N3OS

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Medchemexpress LLC DB04760 (compound 4) | 544678-85-5 | MFCD09878513 | 99.2% | 410.42 g/mol | C22H20F2N4O2 | 10MG

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DB04760 is a small-molecule MMP-13 inhibitor (compound 4) reported as a potent, highly selective, non-zinc-chelating inhibitor with an IC50 of 8 nM. It has been used in studies showing reduction of paclitaxel-induced neurotoxicity and anticancer activity, and is supplied for research use with defined purity and solubility characteristics.

• Potent MMP-13 inhibitor with IC50 = 8 nM.
• Highly selective non-zinc-chelating mechanism.
• Molecular formula C22H20F2N4O2, molecular weight 410.42 g/mol.
• CAS number 544678-85-5.
• Purity 99.2%.
• Soluble in DMSO at ≥100 mg/mL; in vivo formulation: 10% DMSO then 90% corn oil.
• Reported to reduce paclitaxel neurotoxicity and exhibit anticancer activity.
• Available in multiple small-scale pack sizes for research use.

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eMolecules​ Ambeed / 2-(4-(Bromomethyl)phenyl)-4455-tetramethyl-132-dioxaborolane / 1g / 525123326 / A207813 / / 138500-85-3 / MFCD02179493 / 297.000 / C13H18BBrO2

Ambeed / 2-(4-(Bromomethyl)phenyl)-4455-tetramethyl-132-dioxaborolane / 1g / 525123326 / A207813 / / 138500-85-3 / MFCD02179493 / 297.000 / C13H18BBrO2

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Medchemexpress LLC Protostemotinine | 1MG

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Protostemotinine | 1MG

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Medchemexpress LLC SU5205 | 3476-86-6 | 98.02% | 239.24 | 50 MG

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SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM. It inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM.

• Inhibitor of VEGFR2 (FLK-1)
• Inhibits ligand-induced endothelial mitogenesis for VEGF

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eMolecules​ AstaTech / ISOPROPYL(2-NITROPHENYL)SULFANE / 0.25g / 434269003 / W12996 / 95.000 / 70415-85-9 / MFCD13689000 / 197.250 / C9H11NO2S

AstaTech / ISOPROPYL(2-NITROPHENYL)SULFANE / 0.25g / 434269003 / W12996 / 95.000 / 70415-85-9 / MFCD13689000 / 197.250 / C9H11NO2S

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Medchemexpress LLC SU5205 | 98.4% | 100 MG

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SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.

• No clinical development reported

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Medchemexpress LLC 3-(benzylthio)-5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazole | 129544-85-0 | 99.9% | C22H19N3OS | 10MG

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MIND4-19 is a small-molecule SIRT2 inhibitor (IC50 7.0 μM) used as a research tool in studies of neurodegeneration, including Huntington's disease. The compound is a solid, white to off-white material with formula C22H19N3OS and a molecular weight of 373.47 g·mol⁻¹; it is supplied with high purity and storage recommendations to protect activity.

• Potent SIRT2 inhibition (IC50 7.0 μM).
• High chemical purity (>99.9%).
• Solid, white to off-white appearance for easy handling.
• Suitable for neurodegeneration and SIRT2 biology research.
• Storage conditions provided to preserve stability and activity.

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Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 25 MG

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C-021 is a small-molecule CCR4 antagonist supplied for research use. It inhibits CCR4-mediated chemotaxis in human and mouse cells and blocks CCL22-induced GTPγS binding, making it suitable for biochemical and cellular assays.

• Target: CCR4 (GPCR), suitable for immunology and GPCR research.
• Potent CCR4 antagonist with reported IC50s of 140 nM (human chemotaxis), 39 nM (mouse chemotaxis), and 18 nM in GTPγS binding assays.
• Molecular formula C27H41N5O2 and molecular weight 467.65 g/mol.
• Reported purity 99.95% and solid appearance (off-white to light yellow).
• Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
• Intended for research use only; not for human or animal therapeutic use.

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Medchemexpress LLC Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-aze | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 100 MG

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ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor, demonstrating 51-fold selectivity for PS1 with EC50s of 12 nM for PS1 and 656 nM for PS2. It functions as a classic γ-secretase inhibitor, selectively inhibiting Aβ production over Notch signaling in cells. Oral administration *in vivo* leads to an acute reduction of brain Aβ in models of Alzheimer's disease.

• Amyloid precursor protein (APP) selective γ-secretase inhibitor
• Exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase
• Demonstrates 51-fold selectivity for PS1
• Selectively inhibits Aβ production over Notch signaling in cells
• Displaces an active site directed inhibitor *in vitro*
• Leads to acute reduction of brain Aβ *in vivo* in Alzheimer's disease models

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eMolecules​ ChemScene / 4-(Diphenylamino)phenol / 100mg / 536809149 / CS-0110718 / 0.000 / 25069-86-7 / MFCD20259251 / 261.324 / C18H15NO

ChemScene / 4-(Diphenylamino)phenol / 100mg / 536809149 / CS-0110718 / 0.000 / 25069-86-7 / MFCD20259251 / 261.324 / C18H15NO

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Medchemexpress LLC Cadrofloxacin 5mg | 153808-85-6 | 411.38 g·mol⁻1 | C19H20F3N3O4 | 5 MG

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Cadrofloxacin is a fluoroquinolone antibiotic supplied for research use. It is provided as a solid for experimental assays, with manufacturer guidance for solubilization and storage to preserve activity.

• Purity 98.21% as reported by the manufacturer.
• Molecular weight 411.38 g·mol⁻1.
• Soluble in DMSO at about 10 mg/mL with warming and pH adjustment.
• Store powder at -20°C for long-term stability; aliquot solutions to avoid freeze-thaw cycles.
• Suitable for in vitro antibacterial research and assay development.

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eMolecules​ Ambeed / (S)-2-(Benzo[b]thiophen-2-yl)-4-benzyl-45-dihydrooxazole / 50mg / 665578597 / A1493991 / / 2170033-85-7 / [null] / 293.380 / C18H15NOS

Ambeed / (S)-2-(Benzo[b]thiophen-2-yl)-4-benzyl-45-dihydrooxazole / 50mg / 665578597 / A1493991 / / 2170033-85-7 / [null] / 293.380 / C18H15NOS

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Medchemexpress LLC KG5 | 877874-85-6 | C20H16F3N7OS | 50 MG

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KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor, also inhibiting Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic activities, preventing tumor growth and blocking angiogenesis in various models.

• Inhibits vascular smooth muscle cells (VSMCs) and endothelial cell viability
• Selectively blocks S338 phosphorylation
• Inhibits PDGFRα and β, Flt3, and KIT
• Inhibits phosphorylation of MEK and ERK in endothelial cells
• Prevents tumor growth in an orthotopic renal cell carcinoma model
• Completely blocks angiogenesis in mice

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