Azobenzenes
Medchemexpress LLC 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | 274925-86-9 | MFCD09954136 | 99.9% | 273.24 | C14H11NO5 | 100 MG
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor provided as a high-purity research reagent for biochemical and pharmacological studies. It is characterized by known identifiers and physical properties, and is intended for laboratory research use only (not for human use).
- Reversible COMT inhibitor suitable for enzyme assays and pharmacology studies.
- High purity for analytical and experimental consistency.
- Well-characterized identifiers available (CAS, MFCD, InChIKey).
- Soluble in DMSO for preparation of concentrated stock solutions.
- Supplied in a measured 100 mg amount for small-scale experiments.
eMolecules 139139-86-9 | Ambeed | (R)-22-Bis(diphenylphosphino)-55667788-octahydro-11-binaphthyl | 50mg | 588342799 | A525018 | MFCD01630795 | 630.752 | C44H40P2
ChemScene | (R)-1-(4-((Trifluoromethyl)thio)phenyl)ethan-1-amine hydrochloride | 100mg | 569145795 | CS-0101656 | 1800240-39-4 | MFCD24418250 | 257.700 | C9H11ClF3NS
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Medchemexpress LLC 4-MMPB | 928853-86-5 | 313.42 g/mol | C16H19N5S | 25 MG
4-MMPB is a small-molecule research compound that acts as a selective 15-lipoxygenase inhibitor and is provided for laboratory research use only. It has documented enzyme inhibition and cell viability data and is commonly used in biochemical assays and exploratory cellular studies.
- Selective 15-lipoxygenase inhibition (IC50 ≈ 18 μM)
- Molecular formula C16H19N5S; molecular weight 313.42 g/mol
- Soluble in DMSO (7.69 mg/mL; may require sonication)
- Compatible in vivo formulations at ≥ 0.77 mg/mL in multiple vehicle systems
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years)
- Intended for laboratory research use only; not for human or clinical use
Medchemexpress LLC Gsk962 | 2049872-86-6 | 99.2% | 230.31 | C14H18N2O | 25 MG
GSK962 is the inactive enantiomer of GSK963 supplied as a purified small-molecule research reagent for use as a negative control to confirm on-target effects in studies of RIP kinase.
- Inactive enantiomer control for RIP kinase studies.
- High purity (99.18%) suitable for in vitro research.
- Provided as a 25 MG powder for laboratory use.
- Soluble in DMSO; follow SDS and datasheet for handling.
- Certificate of analysis and SDS available for quality verification.
Medchemexpress LLC Rhodojaponin V | 37720-86-8 | MFCD01724481 | 1 MG
Rhodojaponin V is a diterpenoid isolated from the leaves of *Rhododendron molle*. This compound exhibits anti-inflammatory activity and is identified as the C-14 acetylation product of Rhodojaponen III. It is intended for research use only.
- Diterpenoid compound
- Isolated from *Rhododendron molle*
- Exhibits anti-inflammatory activity
- C-14 acetylation product of Rhodojaponen III
- For research use only
Medchemexpress LLC KG5 | 877874-85-6 | C20H16F3N7OS | 100 MG
KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor, also inhibiting Flt3, KIT, and c-Raf. It demonstrates anticancer and antiangiogenic activities.
- Inhibits vascular smooth muscle cells and endothelial cells viability
- Selectively blocks S338 phosphorylation
- Inhibits PDGFRα, PDGFRβ, Flt3, and KIT
- Prevents tumor growth in an orthotopic renal cell carcinoma model
- Completely blocks angiogenesis in mice
- Disrupts angiogenesis during zebrafish embryogenesis
Chemscene ChemScene | Methyl 6-formylnicotinate | 5G | CS-D0517 | 0.98 | 10165-86-3| MFCD08275010 | 165.15
ChemScene | Methyl 6-formylnicotinate | 5G | CS-D0517 | 0.98 | 10165-86-3| MFCD08275010 | 165.15
eMolecules 3138-86-1 | AstaTech | 23-BIS(BROMOMETHYL)QUINOXALINE | 1g | 448261998 | 90455 | 98 | MFCD00006729 | 315.996 | C10H8Br2N2
Ambeed | (4-Chlorophenyl)(dimethoxyphosphoryl)methyl dimethyl phosphate | 1mg | 598442883 | A913260 | 76541-72-5 | MFCD00864813 | 358.650 | C11H17ClO7P2
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Medchemexpress LLC Pegaptanib sodium | 222716-86-1 | 90.51% | 50000 (Approximately) | 500 MG
Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, directed against vascular endothelial growth factor (VEGF)-165. It can be used for the study of neovascular age-related macular degeneration (AMD).
- Solid appearance.
- White to off-white color.
- Inhibits VEGF165-mediated phosphorylation of VEGFR2 and phospholipase Cγ.
- Inhibits VEGF165-induced calcium mobilization in human umbilical vein endothelial cells.
- Targets vascular endothelial growth factor-165.
- Suitable for the study of neovascular age-related macular degeneration.
Medchemexpress LLC Eln318463 racemate | 851599-82-1 | >98% | C19H20BrClN2O3S | 50 MG
ELN318463 racemate is a selective γ-secretase inhibitor, demonstrating differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase. It shows significant selectivity for PS1 with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. This compound acts as a classic γ-secretase inhibitor, inhibiting Aβ production with 75- to 120-fold selectivity over Notch signaling in cells.
- Amyloid precursor protein (APP) selective γ-secretase inhibitor
- Differentially inhibits presenilin (PS1) and PS2-comprised γ-secretase
- 51-fold more selective for PS1
- Demonstrates 75- to 120-fold selectivity for inhibiting Aβ production
- Displaces an active site-directed inhibitor in the presence of a substrate
- Achieves brain levels up to 2.7 μM at 100 mg/kg dose
eMolecules 34042-85-8 | Medchem Express | Sudoxicam | 5mg | 721309281 | HY-106628 | MFCD00866053 | 337.37 | C13H11N3O4S2
AstaTech | N-CARBETHOXY-3-METHOXY-4-PIPERIDONE | 0.25g | 381448120 | 57304 | 97.000 | 83863-72-3 | MFCD02093811 | 201.222 | C9H15NO4
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Medchemexpress LLC Lys006 hydrochloride | 2619563-79-8 | 429.23 | 50 MG
LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 of 2 nM. It is extracted from patent WO2015092740A1, example 29, and is for research use only. It can be used for the research of inflammatory and autoimmune disorders.
- Potent inhibitor of LTA4H hydrolase
- IC50 of 2 nM
- Used for research on inflammatory and autoimmune disorders
- Currently in Phase 2 clinical trials for inflammatory acne, ulcerative colitis, hidradenitis suppurativa, and non-alcoholic fatty liver disease/nonalcoholic steatohepatitis
![Medchemexpress LLC 3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one | 924377-85-5 | MFCD08868156 | 99.1% | 395.52 g/mol | C22H25N3O2S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000264561.png-250.jpg)
Medchemexpress LLC 3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one | 924377-85-5 | MFCD08868156 | 99.1% | 395.52 g/mol | C22H25N3O2S | 5 MG
GSK1702934A is a small-molecule activator selective for TRPC3 and TRPC6 channels used as a research tool to probe TRPC-mediated calcium signaling. It induces TRPC3/6-dependent currents and has been applied to studies of cardiac contractility and arrhythmogenesis in cellular and tissue models. The compound is offered in solid form and as DMSO solution for experimental convenience.
- Selective TRPC3/6 activation for targeted functional studies.
- High purity suitable for biochemical and electrophysiology assays.
- Available as small solid quantities and as DMSO solution for convenience.
- Supports studies of cardiac contractility and arrhythmogenesis.
- Compatible with cellular assays and patch-clamp electrophysiology.
![Medchemexpress LLC 5-chloro-2-fluoro-4-[(1S,2R)-2-(2-methylpyrazol-3-yl)cyclohexyl]oxy-N-pyrimidin-4-ylbenzenesulfonamide | 1450595-86-4 | Not found on authoritative sources | 99.6% | C20H21ClFN5O3S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259338.png-250.jpg)
Medchemexpress LLC 5-chloro-2-fluoro-4-[(1S,2R)-2-(2-methylpyrazol-3-yl)cyclohexyl]oxy-N-pyrimidin-4-ylbenzenesulfonamide | 1450595-86-4 | Not found on authoritative sources | 99.6% | C20H21ClFN5O3S | 10MG
DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor used in pain research. It shows low-nanomolar inhibition of human NaV1.7, activity in rodent models, and has demonstrated analgesic effects in preclinical studies.
- Potent NaV1.7 inhibition: hNaV1.7 IC50 = 22.8 nM; mNaV1.7 IC50 ≈ 59.4 nM.
- Orally active with reported analgesic effects in preclinical models.
- High purity, typically 99.6% by supplier specification.
- Defined chemical identity: CAS 1450595-86-4; formula C20H21ClFN5O3S; MW 465.93 g·mol⁻¹.
- Soluble in DMSO and compatible with common in vivo formulation vehicles.
- Stable as a solid with recommended refrigerated or frozen storage for long-term retention.
![eMolecules 1558023-86-1 | Ambeed | Anthra[219-def6510-def]diisoquinoline-13810(2H9H)-tetrone 29-bis[3-(dimethyloxidoamino)propyl]- | 100mg | 633419517 | A1156199 | 592.652 | C34H32N4O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502452240.PNG-250.jpg)
eMolecules 1558023-86-1 | Ambeed | Anthra[219-def6510-def]diisoquinoline-13810(2H9H)-tetrone 29-bis[3-(dimethyloxidoamino)propyl]- | 100mg | 633419517 | A1156199 | 592.652 | C34H32N4O6
Medchem Express | 5-ROX | 5mg | 446274288 | HY-D0784 | 216699-35-3 | MFCD28355897 | 534.612 | C33H30N2O5
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