Azolines
Apexbio Technology LLC Eicosapentaenoyl Serotonin 199875-71-3 1mg (solution)
Eicosapentaenoyl serotonin (CAS 199875-71-3) is a synthetic hybrid molecule structurally related to arachidonoyl serotonin which is known to inhibit fatty acid amide hydrolase (FAAH) and antagonize transient receptor potential vanilloid 1 (TRPV1) channels resulting in analgesic effects in rodent studies While the substitution of the arachidonoyl moiety with eicosapentaenoic acid has not yet been characterized analogs with different saturated fatty acid chains displayed potent inhibition of TRPV1 channel activation in capsaicin assays Eicosapentaenoyl serotonin is of interest for investigating novel modulation of pain pathways and TRPV1-mediated signaling
Apexbio Technology LLC Serotonin HCl(Synonyms: Serotonin hydrochloride, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride), 10mM (in 1mL DMSO), CAS: 153-98-0.
Serotonin hydrochloride (CAS 153-98-0) is a monoamine neurotransmitter naturally derived from tryptophan that functions as an endogenous agonist of serotonin (5-HT) receptors Additionally serotonin hydrochloride acts as a non-competitive inhibitor of the enzyme catechol O-methyltransferase (COMT) exhibiting a binding affinity (Ki) of approximately 44 M Serotonin modulates diverse physiological processes including mood regulation sleep appetite sexual function and gastrointestinal activity Due to its role in mediating neurological and inflammatory pathways serotonin hydrochloride is widely utilized in research studies investigating depression anxiety disorders migraine pathophysiology and inflammation-associated hypersensitivity
Medchemexpress LLC Creatinine | 60-27-5 | MFCD00004277 | 99.99% | 25 MG
Creatinine (Standard) is an analytical standard of Creatinine, a breakdown product of creatine phosphate found in muscles. It is commonly used for research and analytical applications, particularly in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Analytical standard for Creatinine
- Suitable for research and analytical applications
- Utilized in HPLC, GC and MS experiments
- Derived from creatine phosphate breakdown
- Store at 2-8°C, protected from light.
Medchemexpress LLC Creatinine | 60-27-5 | 99.99% | 113.12 | C4H7N3O | 10 MG
Creatinine (standard) is an analytical reference material supplied as a high-purity solid for research and analytical laboratories. It is used for calibration, method validation, and quality control in quantitative and qualitative creatinine analysis.
- High purity (99.99%) suitable for analytical work.
- CAS number 60-27-5.
- Molecular weight 113.12 g/mol.
- Supplied as a solid in small sizes down to 10 MG.
- Intended for calibration, method validation, and quality control.
- COA and SDS available for traceability and safety.
Medchemexpress LLC 5-HT Serotonin Ant 10uL | 10uL
5-HT (Serotonin) Antibody (YA6451) is a Rabbit-derived and non-conjugated IgG monoclonal antibody targeting to 5-HT (Serotonin)
Medchemexpress LLC Serotonin | 50-67-9 | 99.0% | 100 MG
Serotonin is a monoamine neurotransmitter in the central nervous system (CNS) and acts as an endogenous agonist for 5-HT receptors. It also functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. This product is for research use only and has not been fully validated for medical applications.
- Functions as a monoamine neurotransmitter.
- Acts as an endogenous 5-HT receptor agonist.
- Inhibits catechol O-methyltransferase (COMT).
- Suitable for research use only.
- Not validated for medical applications.
Medchemexpress LLC 1H-indol-5-ol, 3-(2-aminoethyl)- | 50-67-9 | MFCD00055054 | 99.9% | 50 MG
Serotonin, also known as 5-Hydroxytryptamine (5-HT), is a monoamine neurotransmitter in the central nervous system that acts as an endogenous 5-HT receptor agonist. It also functions as a catechol O-methyltransferase (COMT) inhibitor, binding non-competitively to the catechol substrate site with a Kᵢ of 44 μM. Research indicates that 100 μM Serotonin reduces COMT reaction velocity and produces robust hypersensitivity in vivo.
- Monoamine neurotransmitter
- Endogenous 5-HT receptor agonist
- Catechol O-methyltransferase (COMT) inhibitor
- Reduces COMT reaction velocity
- Causes robust hypersensitivity in vivo
Medchemexpress LLC Serotonin hydrochloride | 153-98-0 | 100.0% | 100 MG
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter found in the Central Nervous System (CNS) and acts as an endogenous 5-HT receptor agonist, capable of crossing the blood-brain barrier. It also functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
- Monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist
- Exhibits blood-brain barrier permeability
- Functions as a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM
- Inhibits catechol O-methyltransferase (COMT) via non-competitive binding to the site bound by catechol substrates
- Decreases the reaction velocity of COMT at a concentration of 100 μM
- Produces robust hypersensitivity compared to saline-treated controls (p<0.001)
![eMolecules 77415-55-5 | 2,7-Diazaspiro[4.4]nonane dihydrobromide | Apollo Scientific | MFCD27964259 | 288.027 | C7H16Br2N2 | 95.000 | Br.Br.C1CC2(CCNC2)CN1 | 250mg | 562465505](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502153884.JPG-250.jpg)
eMolecules 77415-55-5 | 2,7-Diazaspiro[4.4]nonane dihydrobromide | Apollo Scientific | MFCD27964259 | 288.027 | C7H16Br2N2 | 95.000 | Br.Br.C1CC2(CCNC2)CN1 | 250mg | 562465505
2,7-Diazaspiro[4.4]nonane dihydrobromide | Apollo Scientific | 77415-55-5 | MFCD27964259 | 288.027 | C7H16Br2N2 | 95.000 | Br.Br.C1CC2(CCNC2)CN1 | 250mg | 562465505
Medchemexpress LLC Irbesartan | 138402-11-6 | 99.9% | 1 ML
Irbesartan (SR-47436) is an orally active Angiotensin II type 1 (AT1) receptor blocker. It helps relax blood vessels, lower blood pressure, and increase blood and oxygen supply to the heart. It is used in research for high blood pressure, heart failure, and diabetic kidney disease.
- Inhibits Angiotensin II-induced proliferation of human aortic smooth muscle cells.
- Inhibits human MATE1-mediated ASP+ uptake in HEK293 cells.
- Acts as an antagonist to Angiotensin II, inhibiting its increase in cytosolic calcium concentration.
- Reduces and suppresses Th22 cells chemotaxis and differentiation.
- Inhibits Th22 cells related proinflammatory responses in TECs.
Medchemexpress LLC Irbesartan | 138402-11-6 | 99.95% | 500 MG
Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB) that can relax blood vessels, lower blood pressure, and increase the supply of blood and oxygen to the heart. It is used for the research of high blood pressure, heart failure, and diabetic kidney disease. This product is for research use only and not for sale to patients.
- Relaxes blood vessels
- Lowers blood pressure
- Increases blood and oxygen supply to the heart
- Used in research for high blood pressure
- Used in research for heart failure
- Used in research for diabetic kidney disease
Apexbio Technology LLC SEROTONIN-5MG
Serotonin (CAS No 50-67-9) is a neurotransmitter primarily involved in regulating mood cognition and various physiological processes Originating from the amino acid tryptophan serotonin s mechanism of action involves binding to its receptors influencing several intracellular pathways including cyclic AMP and diacylglycerol In biomedical research its in vitro activity is commonly observed in the nanomolar to low micromolar range Serotonin is widely used in studies focusing on neurological and psychiatric conditions as well as in drug screening assays Typical applications include the use of cell models and animal studies to explore its effects on brain function and behavior Experimental concentrations typically depend on the specific research design allowing flexibility in adapting the dosages to various models and hypotheses