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Organic heterocyclic compounds that consist of a five-membered ring made up of four carbon atoms and one nitrogen atom, and only one carbon - carbon double bond.
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M-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. This product has an average molecular weight of 2000 and a high purity of 99.8%.
Appears as a white to yellow solid
Store at 4°C under nitrogen
In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Can be shipped at room temperature in the continental US
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VH 101, thiol (compound 20) is a VHL ligand primarily used for the synthesis of PROTACs. This product is intended for research purposes only and not for patient use.
VHL ligand for PROTAC synthesis
Intended for research use only
Molecular weight: 534.67
Appearance: solid
Storage (powder): -20°C for 3 years, 4°C for 2 years
Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Soluble in DMSO: 100 mg/mL
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MPP dihydrochloride is a selective estrogen receptor (ERα) antagonist provided as a high-purity solid for research use in studies of estrogen signaling. It is used in vitro and in vivo to probe ERα-mediated pathways.
High purity: 99.54% (HPLC).
Chemical formula: C29H33Cl2N3O3.
Molecular weight: 542.50 g/mol.
Physical form: solid (white powder).
Storage: store sealed at 4°C; in solution: -80°C (6 months), -20°C (1 month).
Supplied in small milligram quantities for research use.
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Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
Appearance is liquid
Color is colorless to light yellow
Soluble in DMSO
Shipped at room temperature
Pure form can be stored at -20°C for 3 years, 4°C for 2 years
In solvent, can be stored at -80°C for 6 months, -20°C for 1 month
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m-PEG-thiol (MW 10000), also known as mPEG-SH (MW 10000), is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are molecules designed to exploit the ubiquitin-proteasome system for targeted protein degradation.
Purity: 98.0%
Molecular weight: 10000 (average)
Appearance: Solid, white to off-white
Application: Used in the synthesis of PROTACs for targeted protein degradation research
Storage: 4°C, stored under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month (under nitrogen)
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Methimazole, also known as Thiamazole, is an anti-thyroid agent that effectively blocks the production of thyroid hormones from the thyroid gland. This compound is known to potentially cause hepatotoxicity. It is provided as a 10mM solution in 1mL of DMSO.
Available in high purity, typically >99%
Used as an anti-thyroid agent
Blocks thyroid hormone production
Packaged as a 10 mM solution in DMSO
Store powder at -20°C for up to 3 years or 4°C for 2 years
Store solutions in solvent at -80°C for up to 2 years or -20°C for 1 year
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Thiol-PEG3-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands joined by a linker; one ligand binds to an E3 ubiquitin ligase, and the other to the target protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Appearance: Liquid
Color: Colorless to light yellow
Formula: C9H18O5S
Purity: ≥95.0%
Molecular weight: 238.30
Storage (pure form): -20°C for 3 years, 4°C for 2 years
Storage (in solvent): -80°C for 6 months, -20°C for 1 month
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Thiol-PEG4-acid is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting a protein for degradation. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity of 95.0%
Molecular weight: 282.35
Chemical formula: C11H22O6S
Appearance: colorless to light yellow liquid
Storage at 4°C under nitrogen
In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Density: 1.156±0.06 g/cm3
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(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is the S-enantiomer of 3-benzothienylalanine, a chiral alanine derivative bearing a benzo[b]thiophene substituent. It is provided as a solid research reagent for use as a building block or reference standard in medicinal chemistry and biochemical studies.
Chiral S-enantiomer suitable for stereospecific synthesis and stereochemical studies.
Aromatic benzo[b]thiophene substituent at the 3-position.
Molecular formula C11H11NO2S and molecular weight 221.28 g/mol.
Supplied as a solid for laboratory use.
Appropriate as a building block or reference standard in medicinal chemistry workflows.
Store protected from light at 4°C; in solvent: -80°C (6 months), -20°C (1 month).
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