Benzoxadiazoles
Medchemexpress LLC NBD-556 | 333353-44-9 | 99.6% | C17H24ClN3O2 | 50 MG
NBD-556 is a CD4 mimetic and a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. It demonstrates potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Functions as a CD4 mimetic
- Potent HIV-1 entry inhibitor
- Blocks gp120-CD4 interaction
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion
- Inhibits infection of MT-2 cells by laboratory-adapted HIV-1 strains
- Inhibits CD4-dependent virus in a dose-dependent manner
Apexbio Technology LLC NBD-Cl 10199-89-0 500mg
NBD-Cl (10199-89-0) is a fluorescent labeling reagent that covalently reacts with nucleophilic groups specifically amines and thiols It is designed to derivatize these functional groups enabling detection through the formation of highly fluorescent conjugates NBD-Cl exerts its biological utility primarily through its electrophilic reaction mechanism with free amino and thiol groups in biomolecules No specific experimental model or quantitative activity metric is provided Based on these chemical properties NBD-Cl holds research potential in the labeling and detection of amino acid residues peptides proteins and thiol-containing enzymes as well as in studies of enzyme activities and biomolecular interactions
Accela Chembio Inc 4-methyl-2 | 1 | 3-benzoxadiazole | 5g | 29091-40-5 | MFCD00100600 | 97+% | Shelf Life: 1440 Days | Light Sensitive/+4
4-methyl-2 | 1 | 3-benzoxadiazole | 5g | 29091-40-5 | MFCD00100600 | 97+% | Shelf Life: 1440 Days | Light Sensitive/+4
Medchemexpress LLC NBD-Pen | 1955505-54-0 | 99.94% | 25 MG
NBD-Pen is the first fluorescence probe for lipid radicals, offering high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). It specifically detects lipid-derived radicals over other reactive species in biological systems. It directly detects lipid radicals in living cells by turn-on fluorescence and can decrease inflammation, apoptosis, and oxidative stress markers. This probe can be studied in various disease models, such as hepatic carcinoma.
- First fluorescence probe for lipid radicals
- High selectivity and sensitivity (λex: 470 nm, λem: 530 nm)
- Detects lipid-derived radicals over other reactive species
- Directly detects lipid radicals in living cells by turn-on fluorescence
- Decreases inflammation, apoptosis, and oxidative stress markers
- Can be studied in various disease models
Medchemexpress LLC 7-Fluorobenzofurazan-4-sulfonic acid ammonium salt | 84806-27-9 | MFCD02682109 | 99.0% | 5 MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label and probe for thiols, used for detecting dissolved thiol-disulfide compounds such as Cys and GSH, and for pre-column labeling of biological thiols for HPLC. This product is for research use only.
- Fluorescent label and probe for detecting dissolved thiol-disulfide compounds.
- Suitable for pre-column labeling of biological thiols for HPLC.
- Appears as a solid with a light yellow to yellow color.
- Fluorescence excitation at 478 nm and emission at 495 nm.
- Exhibits fluorescence after derivatization with excitation at 385 nm and emission at 524 nm in 0.1 M borate pH 9.5.
- Molecular weight of 235.19.
- Derivatization grade for HPLC.
Medchemexpress LLC Nbd-556 | 333353-44-9 | 99.5% | C17H24ClN3O2 | 100 MG
NBD-556 is a CD4 mimetic and a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. It shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Inhibits HIV-1 entry by blocking gp120-CD4 interaction.
- Shows potent cell fusion and virus-cell fusion inhibitory activity.
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion.
- Inhibits infection of MT-2 cells by laboratory-adapted HIV-1 IIIB, MN, and V32 strains.
- Inhibits CD4-dependent virus in a dose-dependent manner.
Medchemexpress LLC NBD-Pen | 1955505-54-0 | 99.94% | 10 MG
NBD-Pen is the first fluorescence probe for lipid radicals, offering high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). It specifically detects lipid-derived radicals over other reactive species found in biological systems, including H2O2, ClO-, O2•-, and •OH. NBD-Pen directly detects lipid radicals in living cells through turn-on fluorescence. It has been observed to decrease inflammation, apoptosis, and oxidative stress markers, and can be utilized in various disease models such as hepatic carcinoma.
- First fluorescence probe for lipid radicals.
- High selectivity and sensitivity (λex: 470 nm, λem: 530 nm).
- Specifically detects lipid-derived radicals over other reactive species (H2O2, ClO-, O2•-, and •OH).
- Directly detects lipid radicals in living cells by turn-on fluorescence.
- Decreases inflammation, apoptosis, and oxidative stress markers.
- Applicable for studying various disease models, including hepatic carcinoma.
![Medchemexpress LLC Hexanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro | 94885-03-7 | 98.0% | 737.88 g·mol⁻¹ | C36H59N5O11 | 100 UG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285210.png-250.jpg)
Medchemexpress LLC Hexanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro | 94885-03-7 | 98.0% | 737.88 g·mol⁻¹ | C36H59N5O11 | 100 UG
C6 NBD Glucosylceramide is a fluorescently labeled glucosylceramide derivative used to investigate sphingolipid metabolism and intracellular trafficking. The NBD fluorophore on a C6 acyl chain provides fluorescence properties suitable for imaging and plate-based assays, and the material is supplied at high purity for biochemical experiments.
- Fluorescent label suitable for microscopy and plate assays.
- Excitation 466 nm and emission 535 nm for standard fluorescence setups.
- High purity suitable for biochemical and enzymatic assays (98.0%).
- Useful for studying glucosylceramide metabolism and internalization.
- Available in small-scale vials ideal for research applications (100 μg, 500 μg).
Medchemexpress LLC 4-nitro-2,1,3-benzoxadiazol-7-amine | 10199-91-4 | 96.7% | 25 MG
NBD-amine is a fluorogenic amine used as a fluorescent probe and labeling reagent. It fluoresces weakly in aqueous solution and strongly in organic solvents, lipid membranes, and other hydrophobic environments, making it suitable for sensing, labeling, and studies of membrane-associated processes.
- Fluorogenic amine that fluoresces weakly in water and strongly in hydrophobic environments.
- Useful as a fluorescent probe and labeling reagent for synthesis and detection.
- Suitable for studying membrane interactions and lipid environments.
- Provided as a solid with purity 96.7% and molecular weight 180.12 g/mol.
- Documentation available: data sheet, safety data sheet (SDS), and certificate of analysis (COA).
Medchemexpress LLC NBD-F (4-Fluoro-7-nitrobenzofurazan) | 29270-56-2 | 98.9% | 5 MG
NBD-F (4-Fluoro-7-nitrobenzofurazan) is a pro-fluorescent reagent developed for amino acid analysis. It reacts with primary or secondary amines to create a fluorescent product, and is used for the analysis of amino acids and low molecular weight amines.
- Pro-fluorescent reagent for amino acid analysis.
- Reacts with primary or secondary amines to produce a fluorescent product.
- Used for analysis of amino acids and low molecular weight amines.
- Derivatives are highly stable.
- Derivatization procedure is simple.
Medchemexpress LLC MBD (7-(p-methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole) | 33984-50-8 | 99.6% | C14H12N4O4 | 100 MG
MBD is a fluorescent probe utilized for investigating protein and nucleoprotein conformation. It has been successfully applied to bacterial ribosomes as well as bovine trypsinogen and trypsin.
- Fluorescent probe for investigating protein and nucleoprotein conformation.
- Successfully applied to bacterial ribosomes, bovine trypsinogen, and trypsin.
- Strong fluorescence when binding to hydrophobic regions of macromolecules.
Medchemexpress LLC 4-amino-7-nitro-2,1,3-benzoxadiazole | 10199-91-4 | 96.7% | 5MG
4-amino-7-nitro-2,1,3-benzoxadiazole | 10199-91-4 | 96.7% | 5MG
Medchemexpress LLC N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-phosphatidylethanolamine, triethylammonium salt | 178119-00-1 | MFCD00467850 | 95.0% | 956.26 g/mol | C49H90N5O11P | 10 MG
NBD-PE is an NBD-labeled phosphatidylethanolamine fluorescent probe used to label membranes and monitor lipid trafficking and membrane dynamics. It exhibits environment-sensitive green fluorescence (excitation ~463 nm, emission ~526 nm) and is supplied as a solid for laboratory use. CAS 178119-00-1; molecular weight ~956.26 g/mol.
- Green fluorescent NBD label with excitation ~463 nm and emission ~526 nm.
- Integrates into lipid bilayers for membrane labeling and tracking.
- Environment-sensitive fluorescence suitable for monitoring membrane order.
- Available in small laboratory quantities for experimental use.
- Supplied as a solid with a brown to black physical appearance.
- CAS 178119-00-1; molecular weight 956.26 g/mol.
Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | 428.40 | 100 MG
NBD-14189 is a potent HIV-1 entry antagonist, binding to HIV-1 gp120 and demonstrating potent antiviral activity against the HIV-1HXB2 pseudovirus. It shows anti-HIV-1 activity in both single-cycle and multi-cycle assays.
- Potent HIV-1 entry antagonist
- Binds to HIV-1 gp120
- Exhibits potent antiviral activity (EC50 < 200 nM)
- Prevents HIV-1 mediated cell-cell fusion
- Shows weak or no inhibition of the hERG current