Benzoxazines
TARGETMOL CHEMICALS INC MK-2461 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met with a mean IC50 of 2.5 nM. purity: 99%
TARGETMOL CHEMICALS INC WAY-600 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. WAY-600 is a potent ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3K(alpha) (>100-fold) and PI3K(gamma) (>500-fold). purity: 99%
TARGETMOL CHEMICALS INC CDK9-IN-8 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50 12 nM). purity: 98%
Abcam Cinnabarinic acid, Endogenous mGlu4 selective agonist, 10MG
MW 300.22 Da, Purity >98%. Endogenous selective mGlu4 agonist; generated by autoxidation of the tryptophan metabolite 3-hydroxyanthranilic acid. Activates mGlu4 receptors in transiently transfected HEK293 cells, and is devoid of activity on other mGlu receptor subtypes (mGlu1, 2, 5, 6, 7, and 8). Protects against NMDA-induced excitotoxic cell death.
The product is subject to the following: Abcam Restricted Use Statement
Cell Signaling Technology CD19 Intracellular Domain D
CD19 (Intracellular Domain) (D4V4B) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
Cayman Chemical 7-EthoxyresorufIn 1mg
A fluorogenic substrate for, and inhibitor of, CYP1A1; upon enzymatic cleavage by CYP1A1, resorufin is released and its fluorescence can be used to quantify CYP1A1 activity; ex/em = 570/580 nm, respectively; a noncompetitive inhibitor of nNOS (Ki = 0.76 µM)
TARGETMOL CHEMICALS INC SAVIPRAZOLE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Saviprazole (Hoe-731) a proton pump inhibitor is used potentially for treatment of gastric ulcer. purity: 99%
TARGETMOL CHEMICALS INC TRICIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7. purity: 98%
TARGETMOL CHEMICALS INC INOBRODIB 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Inobrodib (CBP-IN-1) is a potent inhibitor of p300/CBP bromodomain. purity: 97%
Cayman Chemical ResorufIn benzyl ether 10mg
A fluorometric probe that acts as a substrate for CYP3A4; typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds and to predict potential drug-drug interactions
Cell Signaling Technology V5-Tag (D3H8Q) Rabbit mAb (Sepharose(R) Bead Conjugate) 400 ul
V5-Tag (D3H8Q) Rabbit mAb (Sepharose(R) Bead Conjugate) 400 ul