Biotin and derivatives
Medchemexpress LLC DBCO-NHS ester 2 500mg | 1384870-47-6 | 430.45 | C25H22N2O5 | 500 MG
DBCO-NHS ester 2 is a dibenzylcyclooctyne (DBCO)-derived N-hydroxysuccinimide (NHS) ester used as an amine-reactive linker for bioconjugation and antibody-drug conjugate synthesis. The reagent enables copper-free click chemistry via strain-promoted alkyne-azide cycloaddition (SPAAC) and is supplied as a powder for laboratory use.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) for copper-free click chemistry.
- Amine-reactive NHS ester for efficient labeling of proteins, peptides, and small molecules.
- Appropriate for antibody-drug conjugate (ADC) linker synthesis and general bioconjugation.
- High reported purity in product documentation.
- Powder form with long-term storage at -20°C; soluble in DMSO (≈14.29 mg/mL) with ultrasonic assistance.
Medchemexpress LLC Biotin-PEG3-benzophenone | 756525-96-9 | MFCD13184950 | 98.7% | 654.82 g/mol | C34H46N4O7S | 10 MG
Biotin-PEG3-benzophenone is a biotin-labeled benzophenone derivative used as a photosensitizer and affinity probe for photolabeling and enrichment of biomolecules. The compound couples a benzophenone photo-crosslinker to a biotin affinity tag via a PEG3 spacer, enabling efficient photolabeling workflows in biochemical and proteomic studies.
- Enables efficient photo-crosslinking and covalent capture of interacting partners.
- Biotin tag allows streptavidin-based enrichment and detection.
- PEG3 spacer improves solubility and reduces steric hindrance.
- High purity suitable for biochemical assays.
TARGETMOL CHEMICALS INC NSP-SA-NHS 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. NSP-SA-NHS is a chemiluminescent acridinium ester that can be used for immunoassays. Purity 98.42%
Sigma Aldrich Fine Chemicals Biosciences (+)-Biotin Hydrazide | 66640-86-6 | MFCD00078532 | 100mg
(+)-Biotin Hydrazide | Purity: 97% | Mol Wt: 258.34 | 66640-86-6 | MFCD00078532 | 100mg
Medchemexpress LLC Ibrutinib-biotin | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 | C56H80N12O9S | 10 MG
Ibrutinib-biotin is a biotinylated chemical probe derived from the BTK inhibitor ibrutinib. The probe links ibrutinib to a biotin tag via a long-chain linker, preserving low-nanomolar inhibitory potency against Bruton's tyrosine kinase while enabling affinity capture and target engagement studies. It is supplied as a high-purity solid and is also available as a DMSO solution for biochemical assays.
- Biotin tag enables affinity capture and pull-down experiments.
- Retains low-nanomolar BTK inhibitory potency for target engagement.
- High purity suitable for biochemical and proteomic workflows.
- Available as solid and as DMSO solution for assay flexibility.
- Useful for mechanism-of-action studies and probe-based profiling.
TARGETMOL CHEMICALS INC DSPE-NHS 25MG
Also available in 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. DSPE-NHS is a lipid that is often combined with other compounds to form nanoemulsions that can be used in skin care products and pharmaceuticals. Purity 99.85%
Medchemexpress LLC DMABA NHS ester | 58068-85-2 | MFCD16875522 | 99.0% | 262.26 g/mol | C13H14N2O4 | 25 MG
DMABA NHS ester is the N-hydroxysuccinimide ester of DMABA, a reactive labeling reagent used to derivatize primary amines for detection and analysis in biochemical workflows. It is supplied as a high-purity solid and is suitable for research applications requiring amine-specific tagging.
- Reactive toward primary amines for labeling and conjugation.
- Suitable for phospholipid, peptide, and protein derivatization for MS or fluorescence detection.
- High purity ensures minimal side products during reactions.
- Supplied as a solid for convenient storage and handling.
- Store sealed, away from moisture; long-term storage at -20°C recommended.
Medchemexpress LLC DBCO-NHS ester | 1353016-71-3 | 99.5% | 402.40 g/mol | C23H18N2O5 | 100 MG
DBCO-NHS ester is an N-hydroxysuccinimide (NHS) activated ester bearing a dibenzocyclooctyne (DBCO) moiety, used as a non-cleavable linker and click-chemistry reagent for bioconjugation and antibody-drug conjugate construction.
- Non-cleavable ADC linker suitable for bioconjugation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners.
- High purity (reported ~99.5%).
- Physical form: solid; color white to yellow.
- Storage: powder -20°C (3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Molecular formula C23H18N2O5; molecular weight 402.40 g/mol.
Apexbio Technology LLC Phos binding reagent (Phosbind) Biotin LC 50mg
Phosbind Biotin LC is a biotin-labeled dinuclear Zn(II) complex that selectively binds phosphorylated molecules at neutral pH (Kd 25 nM to phenyl phosphate) It is widely used in phosphoproteomics workflows to detect phosphoproteins on PVDF membranes via chemiluminescence (with streptavidin-HRP) or enrich phosphorylated peptides/proteins using streptavidin-agarose columns Compared to standard prestained protein markers (e g F4005 with 11 bands from 10 180 kDa) Phosbind enables phospho-specific detection Compatible buffers 20 mM Tris 150 mM NaCl pH 7 5
eMolecules Boc-met-onp | 2488-18-8 | MFCD00038123 | 1g
Combi-Blocks | Boc-met-onp | 1g | 117565039 | SS-8164 | 98.000 | 2488-18-8 | MFCD00038123 | 370.420 | C16H22N2O6S
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Apexbio Technology LLC Cy3 NHS ester (non-sulfonated) 5mg
Cy3 NHS ester (non-sulfonated) is an amine-reactive fluorescent cyanine dye commonly utilized in labeling biomolecules via covalent conjugation to primary amines As a cyanine derivative its fluorescence emission occurs at approximately 570 nm upon excitation near 550 nm allowing detection in the orange spectral region using standard TRITC filter sets commonly integrated in fluorescence microscopy imaging systems and spectroscopic instruments The dye s labeling procedure requires organic solvents such as DMF or DMSO due to its limited aqueous solubility In biomedical research Cy3 NHS ester is routinely employed for labeling peptides proteins nucleic acids and oligonucleotides facilitating visualization and tracking in biomolecular assays cell imaging gel electrophoresis analyses and flow cytometry experiments