Biotin and derivatives
Medchemexpress LLC Azido-PEG6-NHS ester | 2055014-64-5 | 98.0% | 250 MG
Azido-PEG6-NHS ester is a cleavable PEG ADC linker. It is also a PEG- and alkyl/ether-based PROTAC linker. This compound is a click chemistry reagent, featuring an azide group for copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
- Cleavable PEG ADC linker
- Used in antibody-drug conjugate (ADC) synthesis
- PEG- and alkyl/ether-based PROTAC linker
- Suitable for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Medchemexpress LLC DBCO-NHS ester 2 100mg | 1384870-47-6 | 100 MG
DBCO-C6-NHS ester is a DBCO-derived N-hydroxysuccinimide (NHS) ester used to introduce a DBCO handle onto amine-containing molecules for copper-free, strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation and antibody-drug conjugate (ADC) linker synthesis.
- Amine-reactive NHS ester for covalent coupling to primary and secondary amines.
- Facilitates copper-free SPAAC click chemistry with azide-functionalized partners.
- Suitable for bioconjugation, ADC synthesis, and labeling of proteins or small molecules.
- Available in multiple sizes; typical laboratory scale is 100 mg.
- Soluble in DMSO (~14.29 mg/mL); store powder at -20°C for long-term stability.
eMolecules Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Medchemexpress LLC FP-biotin | 259270-28-5 | 99.8% | C27H50FN4O5PS | 10MG
FP-Biotin is a biotinylated fluorophosphonate probe designed to covalently label serine hydrolases for activity-based profiling. The biotin tag enables enrichment and identification of labeled proteins or peptides from plasma and complex samples using avidin/streptavidin capture. Available as a solid and as a DMSO solution for flexible workflows.
- covalently labels serine hydrolases for activity profiling
- enables affinity purification via biotin-avidin interaction
- suitable for plasma and complex biological samples
- supplied as solid or ready-to-use solution for workflow flexibility
- high purity for reproducible results
- supported by data sheet, COA, and SDS for quality and safety
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 g/mol | C38H64N2O21 | 25 MG
Bis-PEG13-NHS ester is a PEG-based N-hydroxysuccinimide (NHS) ester linker for research use in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Provides a bifunctional PEG13 spacer for conjugation to amines.
- Reactive NHS ester termini enable efficient coupling.
- High purity suitable for research applications.
- Molecular weight approximately 884.92 g/mol; molecular formula C38H64N2O21.
- Available in small pack sizes for research-scale synthesis.
Medchemexpress LLC Bis-PEG6-NHS ester | 1526718-98-8 | 98.0% | 576.55 g/mol | C24H36N2O14 | 50 MG
Bis-PEG6-NHS ester is a PEG-based bifunctional linker bearing two N-hydroxysuccinimide (NHS) ester termini separated by a six-unit polyethylene glycol spacer. It is used to conjugate amine-containing ligands in the synthesis of PROTACs and as a cleavable linker for antibody-drug conjugates (ADCs).
- High purity (98.0%).
- Two NHS ester termini for efficient amine coupling.
- PEG6 spacer provides aqueous solubility and conformational flexibility.
- Suitable as a cleavable linker in ADC construction and for PROTAC linker design.
- Store sealed at -20 °C, away from moisture; unstable in solution, prepare fresh as needed.
Medchemexpress LLC PC biotin-PEG3-NHS ester | 2353409-93-3 | 840.89 | C36H52N6O15S | 10 MG
PC Biotin-PEG3-NHS ester is a cleavable 3-unit polyethylene glycol (PEG3) biotinylation reagent bearing an N-hydroxysuccinimide (NHS) active ester. It is used as a cleavable ADC linker and for biotinylation of primary amines in peptides, proteins, and other biomolecules to enable affinity capture or detection. The product is supplied as a solid and should be stored as a powder at -20°C; solutions have shorter storage lifetimes. Handle only by trained personnel for research use.
- Cleavable PEG3 biotin linker for ADC conjugation and labeling
- Reactive NHS ester for selective labeling of primary amines
- Molecular weight 840.89 and formula C36H52N6O15S
- Solid appearance; store powder at -20°C for long-term stability
- Intended for laboratory research use only
Medchemexpress LLC Biotin-PEG-Thiol (MW 2000) | 98.0% | 2000 (Average) | 25 MG
Biotin-PEG-Thiol (MW 2000) is an active compound that is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. It can modify biomolecules, proteins, peptides, and other small molecule materials and is widely used in research concerning agent release and nano new materials.
- Functions as an active compound.
- Pegylated for high affinity and specificity binding to streptavidin or antibiotin.
- Capable of modifying biomolecules, proteins, peptides, and other small molecule materials.
- Widely used in research concerning agent release and nano new materials.
- Solid, white to off-white appearance.
- Store at -20°C, protected from light, and under nitrogen.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen.
- Soluble in DMSO at 125 mg/mL (requires ultrasonication).