Biotin and derivatives
Apexbio Technology LLC Cy3 NHS ester(Et)(Synonyms: Cy3 NHS ester, Cy3 NHS Ester (ethyl), Cyanine3 NHS ester, Cyanine 3 NHS ester, Cy3 Mono NHS Ester), 25mg.
Cy3 NHS ester(Et) is a small molecule commonly employed in biomedical research as a reactive fluorescent reagent Through its N-hydroxysuccinimide (NHS) ester functionality it readily forms stable covalent linkages with primary amine groups present on proteins peptides and other biomolecules Due to its fluorescent character Cy3 NHS ester(Et) is extensively utilized for labeling biological targets enabling visualization and tracking in fluorescence microscopy and imaging analyses This property facilitates investigations into molecular localization trafficking processes and pathology-associated pathways in various experimental models
Medchemexpress LLC Mal-PEG3-C1-NHS ester | 2230016-26-7 | 95.0% | 384.34 g/mol | C16H20N2O9 | 25 MG
Mal-PEG3-C1-NHS ester is a non-cleavable, three-unit polyethylene glycol (PEG) linker bearing maleimide and N-hydroxysuccinimide (NHS) ester functional groups, designed for use in antibody-drug conjugate (ADC) synthesis and related bioconjugation research.
- Non-cleavable three-unit PEG linker
- Contains maleimide and NHS ester functional groups
- Enables conjugation to thiols and amines for ADC assembly
- Purity ≥95.0% and molecular weight 384.34 g/mol
- Available in small milligram packaging for research applications
Medchemexpress LLC Azido-PEG12-NHS ester | 2363756-50-5 | 98.0% | C31H56N4O16 | 50 MG
Azido-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC BHQ-2 NHS | 916753-62-3 | 97.7% | 603.58 | 50 MG
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. It has a wide and intense quenching range from 560-670 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications with orange to far-red emitting dyes. The NHS ester can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester.
- Wide and intense quenching range from 560-670 nm.
- Useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes.
- NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Chemscene ChemScene | Azido-PEG11-amine | 100MG | CS-0114594 | 0.95 | 1800414-71-4| MFCD08274605 | 570.67
ChemScene | Azido-PEG11-amine | 100MG | CS-0114594 | 0.95 | 1800414-71-4| MFCD08274605 | 570.67
TARGETMOL CHEMICALS INC DOTA-NHS-ester 10MG
Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. DOTA-NHS-ester is a linker for affibody molecules with applications in small animal PET, SPECT, and CT. It can be used to label radiotherapeutic agents or imaging probes for tumor detection. Purity ≥98%
Sigma Aldrich Fine Chemicals Biosciences Biotin meets USP testing specifications | 58-85-5 | MFCD00005541 | 5G
Biotin meets USP testing specifications | Purity: 97.5-102.0% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5G
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 | C38H64N2O21 | 100 MG
Bis-PEG13-NHS ester is a polyethylene glycol (PEG)-based NHS ester linker supplied for research use in bioconjugation, antibody-drug conjugate (ADC) synthesis, and PROTAC linker construction. It reacts with primary amines to form amide bonds, enabling stable attachment of payloads to biomolecules.
- Peg/alkyl/ether-based linker suitable for conjugation chemistry.
- Reactive NHS ester functional group for coupling to primary amines.
- Cleavable linker properties useful for ADC and PROTAC designs.
- Available in multiple pack sizes, including a 100 MG option.
- High purity, typically around 98.0%.
Medchemexpress LLC Diazo biotin-PEG3-azide | 1339202-33-3 | 95.5% | C33H45N9O7S | 25 MG
Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that have DBCO or BCN groups. PROTACs themselves consist of two different ligands linked together, one targeting an E3 ubiquitin ligase and the other a specific protein, leveraging the intracellular ubiquitin-proteasome system to degrade target proteins selectively.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition reactions
- Undergoes strain-promoted alkyne-azide cycloaddition reactions
Medchemexpress LLC Biotin-PEG-Biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 25 MG
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC N-succinimidyl 4-(dimethylamino)benzoate | 58068-85-2 | MFCD16875522 | 99.0% | 262.26 g/mol | C13H14N2O4 | 10 MG
DMABA NHS ester is an N-hydroxysuccinimide (NHS) ester reagent used to derivatize primary amine groups of phosphatidylethanolamine (PE) lipids, enabling selective detection by mass spectrometry. It is supplied as a white to off-white solid with high purity and recommended cold storage to preserve activity.
- Enables selective labeling of PE lipids for precursor ion scanning.
- Improves detection sensitivity in electrospray tandem mass spectrometry.
- High purity supports reliable analytical results.
- Stable as supplied with recommended low-temperature, moisture-free storage.
- Compatible with isotope-labeled DMABA analogs for comparative analyses.
Medchemexpress LLC Bis-PEG21-NHS ester | 2221948-98-5 | 98.0% | 1237.34 g/mol | C54H96N2O29 | 25 MG
Bis-PEG21-NHS ester is a PEG/alkyl/ether-based linker used in the synthesis of PROTACs and as a cleavable linker for antibody-drug conjugates (ADCs). It is supplied as a solid with high purity and defined storage recommendations.
- PEG/alkyl/ether-based linker
- Cleavable linker suitable for ADC synthesis
- Used in the construction of PROTAC molecules
- High purity (98.0%)
- Molecular weight 1237.34 g/mol
- CAS number 2221948-98-5
- Powder storage: -20°C for long-term stability