Biotin and derivatives
Medchemexpress LLC Sulfo-Cy3-NHS disodium | 865.90 g/mol | C36H41N3Na2O13S3 | 10 MG
Sulfo-Cy3-NHS disodium is a water-soluble Cyanine3 (Cy3) derivative bearing an NHS ester for amine-reactive conjugation. The sulfonate groups increase aqueous solubility, making this reagent suitable for labeling proteins, peptides, and antibodies for fluorescence detection and imaging.
- Water-soluble NHS ester for efficient labeling of primary amines.
- Improved aqueous solubility due to sulfonate groups.
- Suitable for conjugation to proteins, antibodies, and peptides.
- Enables fluorescence detection and imaging applications.
- Stable solid form for routine laboratory handling and storage per manufacturer instructions.
Medchemexpress LLC PD-L1 Human Biotin 20ug
Recombinant, biotinylated human PD-L1 produced in HEK293 cells and supplied as a lyophilized 20 μg vial for research use. The protein includes C-terminal human Fc and Avi tags, is characterized for purity and molecular mass, and exhibits specific binding activity suitable for PD-1/PD-L1 interaction and immunoassay applications.
- Expressed in HEK293 mammalian cells.
- Contains C-terminal human Fc and Avi tags.
- Site-specific biotinylation via Avi tag.
- Purity greater than 95% by reducing SDS-PAGE.
- Lyophilized from 20 mM PB, 150 mM NaCl, pH 7.4.
- Predicted molecular mass 54.2 kDa; apparent 70-95 kDa by SDS-PAGE.
- Demonstrated binding activity with ED50 of 15.30 ng/mL.
- Store frozen and aliquot after reconstitution for long-term stability.
Medchemexpress LLC PCSK9 Human Biotin 20ug
The PCSK9 protein is an important regulator of plasma cholesterol homeostasis affecting LDL receptor family members such as LDLR and VLDLR It promotes their intracellular degradation and enhances hepatic LDLR degradation through non-proteolytic mechanisms PCSK9 Protein Human (Biotinylated V474I G670E HEK293 Avi) is the recombinant human-derived PCSK9 protein expressed by HEK293 with C-Avi labeled tag and V474I G670E mutation
Medchemexpress LLC GGGYK-Biotin | 99.8% | 706.81 | 10 MG
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. It can be used to develop Sortase A variants with different substrate specificities.
- Purity of 99.75%
- Molecular weight of 706.81
- Appears as a white to off-white solid
- Sequence: Gly-Gly-Gly-Tyr-Lys-Biotin
- Formula: C31H46N8O9S
Medchemexpress LLC Pomalidomide-C3-NHS ester | 2828476-87-3 | 98.7% | 456.41 | 50 MG
Pomalidomide-C3-NHS ester is a synthesized E3 ligase ligand-linker conjugate, incorporating the Pomalidomide based cereblon ligand and NHS ester linker. This product is intended for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Includes NHS ester linker
- Stable under recommended storage conditions
- Ships at room temperature in continental US
- Stores at 4°C, sealed, away from moisture
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC IL-13 Human Biotin 100ug
IL-13 protein is a cytokine involved in allergic inflammation immune response to parasites and B cell proliferation IL-13 Protein Human (Biotinylated HEK293 Avi-His) is the recombinant human-derived IL-13 protein expressed by HEK293 with C-Avi C-6 His labeled tag
Medchemexpress LLC Biotin-PEG12-NHS ester | 1934296-88-4 | 99.31% | C41H72N4O18S | 25 MG
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Utilizes intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Biotin-PEG2-NHS ester | 596820-83-6 | 96.7% | C21H32N4O8S | 25 MG
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. One ligand is for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand is for an E3 ubiquitin ligase
- Other ligand is for the target protein
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Mal-PEG6-NHS ester | 1599472-25-9 | MFCD20926374 | 98.0% | 530.52 g/mol | C23H34N2O12 | 1 G
Mal-PEG6-NHS ester is a non-cleavable ADC linker containing a maleimide reactive group, a six-unit polyethylene glycol (PEG6) spacer, and an N-hydroxysuccinimide (NHS) ester for amine coupling. It is supplied for research use in synthesis and bioconjugation workflows.
- Purity 98.0%.
- Cas number 1599472-25-9.
- Molecular weight 530.52 g/mol.
- Chemical formula C23H34N2O12.
- Soluble in DMSO at 100 mg/mL (in vitro; ultrasonic recommended).
- Suggested in vivo formulations provided for dosing preparations.
- For research use only; not for use in patients.
- Pack quantity 1 G.
Medchemexpress LLC NHS-PEG1-SS-PEG1-NHS | 1688598-83-5 | 98.0% | 436.41 | 200 MG
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecules.
- Functions as a reversible linker
- Enables biomacromolecule linkage with active small molecules
- Applicable in proteins
- Applicable in liposomes
- Applicable in nanoparticles
Medchemexpress LLC Biotin-C10-NHS ester | 887628-40-2 | MFCD05865045 | 99.5% | 524.67 | C25H40N4O6S | 5 MG
Biotin-C10-NHS ester is an alkyl/ether-based PROTAC linker bearing an N-hydroxysuccinimide (NHS) ester and a ten-carbon biotin spacer. It reacts with primary amines to install a biotin handle for affinity capture, target identification, and PROTAC probe construction. The compound is supplied as a solid with reported high purity and recommended low-temperature storage to maintain stability.
- Alkyl/ether-based PROTAC linker suited for probe design.
- NHS ester for efficient coupling to primary amines.
- Ten-carbon biotin spacer for robust affinity capture.
- Supplied as a solid with reported high purity.
- Storage conditions preserve stability (powder -20°C).
Medchemexpress LLC 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-Heneicosaoxaheptahexacontanedioic acid, 1,67-bis(2,5-dioxo-1-pyrrolidinyl) ester | 2221948-98-5 | 99.89% | 250 MG
Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker that can be utilized in the synthesis of PROTACs. It also serves as a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Can be used in the synthesis of PROTACs.
- Serves as a cleavable ADC linker.