Biotin and derivatives
Biotin, Powder, FCC, 97.5-100.5%, Spectrum™ Chemical
CAS: 58-85-5 Molecular Formula: C10H16N2O3S Molecular Weight (g/mol): 244.31 MDL Number: MFCD00005541 InChI Key: YBJHBAHKTGYVGT-UHFFFAOYNA-N IUPAC Name: 5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanoic acid SMILES: OC(=O)CCCCC1SCC2NC(=O)NC12
Biotin, Powder, USP, 97.5-102%, Spectrum™ Chemical
CAS: 58-85-5 Molecular Formula: C10H16N2O3S Molecular Weight (g/mol): 244.31 MDL Number: MFCD00005541 InChI Key: YBJHBAHKTGYVGT-UHFFFAOYNA-N IUPAC Name: 5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanoic acid SMILES: OC(=O)CCCCC1SCC2NC(=O)NC12
Medchemexpress LLC Biotin-TEG-ATFBA | 1264662-85-2 | MFCD13184978 | 99.1% | 663.68 | C27H37F4N7O6S | 10 MG
Biotin-TEG-ATFBA is a biotin-labeled click chemistry reagent containing a perfluorophenylazide group. Upon photolysis it forms a stable azene intermediate that participates in insertion and cycloaddition reactions, enabling bioconjugation and linker construction for research applications. The compound is supplied as a solid with high purity and is intended for laboratory use.
Medchemexpress LLC Biotin-PEG1-azide | 1204085-48-2 | 99.9% | 356.44 g/mol | C14H24N6O3S | 10 MG
Biotin-PEG1-azide is a biotinylated polyethylene glycol (PEG1) azide reagent used as a cleavable linker and click chemistry handle for bioconjugation and antibody-drug conjugate synthesis. It provides an azide functional group for copper-catalyzed or strain-promoted azide-alkyne cycloaddition, enabling attachment to alkyne-containing partners.
- Biotinylated PEG1 structure with terminal azide functional group.
- Suitable for CuAAC and SPAAC click chemistry reactions.
- High purity for research applications.
- Oil appearance; store frozen for stability.
- Available in small milligram pack sizes for laboratory use.
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | MFCD21363287 | 98.0% | 884.92 | C38H64N2O21 | 10 MG
Bis-PEG13-NHS ester is a PEG/alkyl/ether-based bifunctional linker bearing NHS ester reactive groups for conjugation to primary amines. It is used as a cleavable linker for antibody-drug conjugates and as a linker in PROTAC synthesis to enable targeted bioconjugation and protein degradation.
- Contains two NHS ester reactive groups for conjugation to primary amines.
- Suitable as cleavable linker for antibody-drug conjugates and PROTAC synthesis.
- High purity, typically 98.0%.
- Molecular weight 884.92 and formula C38H64N2O21.
- Store sealed, away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
Medchemexpress LLC Sulfo-NHS-LC-LC-biotin | 194041-66-2 | 99.3% | 669.74 g/mol | C26H40N5NaO10S2 | 10 MG
Sulfo-NHS-LC-LC-Biotin is a water-soluble, amine-reactive biotinylation reagent that contains a sulfo-NHS ester joined to biotin via a long-chain spacer arm to reduce steric hindrance and improve labeling efficiency. It reacts selectively with primary amines to form stable amide bonds and is commonly used to label proteins on intact exosomes and cell surfaces.
- Water soluble sulfo-NHS ester for aqueous labeling.
- Long-chain spacer reduces steric hindrance and improves accessibility.
- Reacts selectively with primary amines to form stable amide bonds.
- Suitable for labeling proteins on intact exosomes and crowded surfaces.
- Provided as a small-quantity powder for convenient handling in research workflows.
Medchemexpress LLC Butanoic acid NHS ester (BHQ-1) | 916753-61-2 | 95.4% | 601.61 g/mol | C30H31N7O7 | 10 MG
BHQ-1 NHS is an N-hydroxysuccinimide (NHS) ester derivative of a non-fluorescent quencher designed for covalent coupling to primary amines on nucleotides, oligonucleotides, and other biomolecules. It is intended for use as a quencher in fluorescence probe and assay design and for direct labeling of fluorescently labeled nucleotides. For research use only.
- Reactive NHS ester for stable amide bond formation with amines.
- Non-fluorescent quenching suitable for fluorescence-based assays.
- High purity, typically 95.44% as stated on the COA.
- Soluble in DMSO at approximately 4.35 mg/mL; ultrasonic agitation recommended.
- Provided in milligram quantities for small-scale labeling workflows.
Medchemexpress LLC BHQ-2 N-hydroxysuccinimide ester | 916753-62-3 | MFCD28160399 | 97.7% | 603.58 g/mol | C29H29N7O8 | 10 MG
BHQ-2 NHS is a non-emitting quencher containing a polyaromatic-azo backbone with a terminal N-hydroxysuccinimide (NHS) ester. It is designed for covalent labeling of primary amines on proteins and amine-modified oligonucleotides, and for use as an acceptor in fluorescence resonance energy transfer (FRET) and other fluorescence-based assays.
- Provides strong quenching across 560-670 nm.
- NHS ester reacts with primary amines for covalent labeling.
- High purity, approximately 97.7%.
- Molecular weight 603.58 g/mol.
- Suitable for oligonucleotide and protein labeling in FRET assays.
Medchemexpress LLC N-succinimidyl 4-(dimethylamino)benzoate | 58068-85-2 | MFCD16875522 | 99.0% | 262.26 g/mol | C13H14N2O4 | 10 MG
DMABA NHS ester is an N-hydroxysuccinimide (NHS) ester reagent used to derivatize primary amine groups of phosphatidylethanolamine (PE) lipids, enabling selective detection by mass spectrometry. It is supplied as a white to off-white solid with high purity and recommended cold storage to preserve activity.
- Enables selective labeling of PE lipids for precursor ion scanning.
- Improves detection sensitivity in electrospray tandem mass spectrometry.
- High purity supports reliable analytical results.
- Stable as supplied with recommended low-temperature, moisture-free storage.
- Compatible with isotope-labeled DMABA analogs for comparative analyses.
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-NHS (DSPE-NHS) | 1383932-86-2 | MFCD34561791 | 95.0% | 945.2 g/mol | C49H89N2O13P | 10 MG
DSPE-NHS is an N-hydroxysuccinimide (NHS) ester functionalized distearoyl phosphoethanolamine used for bioconjugation and liposome formation. The reagent self-assembles into lipid bilayers in aqueous solution, and the NHS ester reacts selectively with primary amines to form stable amide bonds, enabling antibody labeling and attachment of amine-containing molecules for nanoparticle and drug-delivery applications.
- Reactive NHS ester for covalent coupling to primary amines.
- Self-assembles into lipid bilayers in aqueous solution.
- Enables antibody labeling and protein conjugation.
- Suitable for liposome and nanocarrier preparation.
- Long-term storage recommended at -20 °C, sealed and protected from moisture and light.
![Medchemexpress LLC Carbonic acid, bicyclo[2.2.1]hept-5-en-2-yl (2,5-dioxo-1-pyrrolidinyl) ester | 1888335-48-5 | 92.1% | 251.24 g/mol | C12H13NO5 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286309.png-250.jpg)
Medchemexpress LLC Carbonic acid, bicyclo[2.2.1]hept-5-en-2-yl (2,5-dioxo-1-pyrrolidinyl) ester | 1888335-48-5 | 92.1% | 251.24 g/mol | C12H13NO5 | 10 MG
Norbornene-NHS is a click-chemistry reagent that functions as a norbornene-derived NHS carbonate dienophile for inverse electron-demand Diels-Alder (IEDDA) conjugation with tetrazines. It is provided for research use to enable efficient amine bioconjugation and labeling applications.
- Dienophile for inverse electron-demand Diels-Alder (IEDDA) conjugation with tetrazines.
- NHS carbonate functional group enables efficient coupling to primary amines.
- Available in small quantities suitable for labeling and bioconjugation experiments.
- Typical purity about 92.1% and molecular weight 251.24 g/mol.
- Store sealed and away from moisture; solid at -20°C; in solvent: -80°C for up to 6 months, -20°C for 1 month.
- Supplied for research use only.
![Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203370.png-250.jpg)
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl 3-((2-(((((1R,8S,9S)-bicyclo[6.1.0]non-4-yn-9-yl)methoxy)carbonyl)amino)... | 95.0% | 454.56 g/mol | C20H26N2O6S2 | 10 MG
BCN-SS-NHS is a cleavable linker reagent containing an NHS ester and a strained bicyclo[6.1.0]nonyne (BCN) moiety. It is used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry and to introduce a cleavable disulfide-containing linker arm in bioconjugation and antibody-drug conjugate synthesis.
- Used for SPAAC click chemistry
- Contains an NHS ester for efficient amine coupling
- Includes a disulfide-cleavable linker for intracellular release
- Suitable for antibody-drug conjugate and bioconjugation workflows
- Available in small-scale research quantities
Research Products International Corp D Biotin 5 G
CAS Number: 58-85-5
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.3
TARGETMOL CHEMICALS INC Biotin-azide 5MG
Also available in 1 mL, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Biotin-azide (N-(3-Azidopropyl)biotinamide) is used for preparing various biotin affixes and identifying proteins. Purity 99.69%
Medchemexpress LLC Bis-PEG2-NHS ester | 65869-63-8 | 99.2% | 400.34 | C16H20N2O10 | 100 MG
Bis-PEG2-NHS ester is a non-cleavable two-unit polyethylene glycol (PEG) linker intended for antibody-agent conjugation (ADC) research applications. It provides NHS ester reactive groups for coupling to amines and is used in bioconjugation workflows to construct antibody-drug conjugates.
- Non-cleavable 2-unit PEG linker for antibody-agent conjugation.
- Purity 99.24% as reported by the manufacturer.
- Molecular weight 400.34 g/mol.
- Chemical formula C16H20N2O10.
- CAS number 65869-63-8.
- Appearance solid, white to off-white.
- Storage: powder -20°C (stable for 3 years); in solvent -80°C (6 months) or -20°C (1 month).
- Package size options include 100 mg, 250 mg, 1 g, 5 g, 10 g, and 50 g.
- Manufacturer documents available: data sheet, safety data sheet, certificate of analysis, handling instructions, H NMR, RP-HPLC, and mass spectrometry data.