Biotin and derivatives
Research Products International Corp D Biotin 5 G
CAS Number: 58-85-5
Molecular Formula: C10H16N2O3S
Molecular Weight: 244.3
Medchemexpress LLC Sulfo-NHS-Biotin sodium | 194041-65-1 | 95.0% | 443.43 | 1 ML
Sulfo-NHS-Biotin sodium is a low-molecular-weight (443.4 Da) tracer designed to assess blood-brain barrier permeability. It is intended for research use only.
- Low molecular weight tracer
- Assesses blood-brain barrier permeability
- Utilized in traumatic brain injury models
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | 90.0% | 400.38 | C16H24N4O8 | 10 MG
NOTA-NHS ester is an N-hydroxysuccinimide (NHS) ester used to conjugate a NOTA chelator to biomolecules for subsequent fluorescent or radioactive nuclide labeling in research applications. It is supplied as a solid reagent with defined molecular characteristics for use in radiopharmaceutical and probe development.
- Provides an NHS-ester functional group for amine conjugation.
- Suitable for fluorescent labeling and radioactive nuclide labeling applications.
- Documented molecular formula C16H24N4O8 and molecular weight 400.38.
- Available in small research pack sizes for synthesis and probe preparation.
- Typically soluble in DMSO for conjugation reactions.
Medchemexpress LLC Biotin-sar-oh | 154024-76-7 | 315.39 | C13H21N3O4S | 1 G
Biotin-sar-oh is a cleavable antibody-drug conjugate (ADC) linker bearing a biotin functionality, used in the synthesis of antibody-drug conjugates and probe development.
- Cleavable ADC linker for conjugation and release strategies.
- Biotinylated for affinity capture and detection.
- Molecular formula: C13H21N3O4S; molecular weight: 315.39.
- Available pack sizes: 250 mg and 1 g.
- CAS number: 154024-76-7.
Medchemexpress LLC Biotin-PEG4-OH | 1217609-84-1 | 98.0% | 100 MG
Biotin-PEG4-OH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It is intended for research use only and is not sold to patients.
- Molecular weight of 419.54
- Molecular formula of C18H33N3O6S
- Appears as a solid
- Color is white to off-white
- Purity is 98.0%
- Identified for laboratory chemicals and manufacturing
- Stable under recommended storage conditions
Medchemexpress LLC Sulfo-NHS-Biotin sodium | 194041-65-1 | 95.0% | 443.43 Da | 100 MG
Sulfo-NHS-Biotin sodium is a low-molecular-weight tracer (443.4 Da) that is used to assess blood-brain barrier permeability. It functions as a passive tracer in animal models of traumatic brain injury, helping to measure blood-brain barrier leakage volume without exhibiting inherent pharmacodynamic effects.
- Low-molecular-weight (443.4 Da) tracer
- Assesses blood-brain barrier permeability
- Functions as a passive tracer
- No inherent pharmacodynamic effects
- Suitable for research use
Medchemexpress LLC Sulfo-NHS-Biotin sodium | 194041-65-1 | 95.0% | 443.43 | 25 MG
Sulfo-NHS-Biotin sodium is a low-molecular-weight tracer (MW 443.4 Da) that can be used to assess blood-brain barrier permeability. It serves as a passive tracer for detecting blood-brain barrier leakage in mouse models of traumatic brain injury.
- Low-molecular-weight tracer
- Assesses blood-brain barrier permeability
- Used as a passive tracer for detecting blood-brain barrier leakage
- Suitable for mouse models of traumatic brain injury
- For research use only
Medchemexpress LLC Mal-PEG8-NHS ester | 2055033-05-9 | 99.0% | 50 MG
Mal-PEG8-NHS ester is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It appears as a colorless to light yellow viscous liquid, intended solely for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
- Appearance: viscous liquid
- Color: colorless to light yellow
- Molecular formula: C27H42N2O14
- Molecular weight: 618.63
- Solubility in DMSO: ≥ 100 mg/mL
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 g/mol | C38H64N2O21 | 25 MG
Bis-PEG13-NHS ester is a PEG-based N-hydroxysuccinimide (NHS) ester linker for research use in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs).
- Provides a bifunctional PEG13 spacer for conjugation to amines.
- Reactive NHS ester termini enable efficient coupling.
- High purity suitable for research applications.
- Molecular weight approximately 884.92 g/mol; molecular formula C38H64N2O21.
- Available in small pack sizes for research-scale synthesis.
Medchemexpress LLC NHS-modified monomethyl auristatin F (TFA salt) | 1404073-10-4 | 96.0% | 1051.32 g/mol | C55H86N8O12 | 10 MG
NHS-Modified MMAF TFA is an NHS-activated derivative of monomethyl auristatin F provided as the trifluoroacetic acid (TFA) salt and used as a drug-linker intermediate for preparing antibody-drug conjugates (ADCs).
- NHS-activated ester for efficient conjugation to primary amines
- Provided as the TFA salt for isolation and handling
- Intended as a drug-linker intermediate for ADC synthesis
- Molecular formula C55H86N8O12; molecular weight 1051.32 g/mol
- Commonly supplied in a 10 mg pack size
Medchemexpress LLC Sulfo-NHS-biotin (sodium) | 194041-65-1 | 95.0% | 443.43 | 50 MG
Sulfo-NHS-Biotin sodium is a low-molecular-weight tracer used to assess blood-brain barrier permeability. It functions as a passive tracer for detecting blood-brain barrier permeability in mouse models of traumatic brain injury. No inherent pharmacodynamic effects have been observed for this product.
- Low-molecular-weight tracer
- Used to assess blood-brain barrier permeability
- Detects blood-brain barrier permeability in mouse models of traumatic brain injury
- Serves as a passive tracer
- No inherent pharmacodynamic effects observed
Sigma Aldrich Fine Chemicals Biosciences Biotin, 58-85-5, MFCD00005541, 1g
Empirical Formula (Hill Notation) C10H16N2O3S, ≥99% (HPLC), Molecular Weight 244.31, lyophilized powder, Synonym: D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H; Biotin may be used to elute proteins from avidin/streptavidin resins.
Medchemexpress LLC Cyclooctyne-O-NHS ester | 1425803-45-7 | 95.0% | 279.29 g/mol | C14H17NO5 | 25 MG
Cyclooctyne-O-NHS ester is an NHS-activated cyclooctyne reagent used for bioconjugation and antibody-drug conjugate synthesis. It couples to primary amines to form stable amide bonds and participates in strain-promoted azide-alkyne cycloaddition (click chemistry) workflows.
- N-hydroxysuccinimide (NHS) activated ester for efficient amide coupling.
- Strained cyclooctyne enables copper-free click reactions with azides.
- Molecular formula C14H17NO5 and molecular weight 279.29 g/mol.
- High purity for research use (95.0%).
- White to off-white solid; store at -20°C under nitrogen.
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | 501.49 g/mol | C20H31N5O10 | 1 G
DOTA-NHS-ester is an amine-reactive DOTA derivative (N-hydroxysuccinimide ester) used to conjugate chelators to peptides, proteins, and other biomolecules for radiolabeling and imaging probe preparation in PET and SPECT studies. It has formula C20H31N5O10 and molecular weight 501.49 g/mol. Manufacturer documents such as a datasheet, SDS, and COA are available.
- Amine-reactive NHS-ester for conjugation.
- Suitable for radiolabeling and imaging probe preparation.
- Chelator compatible with common radiometals.
- Molecular weight 501.49 g/mol.
- CAS number 170908-81-3.
- Supplied in research pack sizes including 1 g.
Medchemexpress LLC NOTA-NHS ester | 1338231-09-6 | MFCD30747764 | ≥97.0% | 400.38 g/mol | C16H24N4O8 | 25 MG
NOTA-NHS ester is a bifunctional chelator derivative used for fluorescent labeling and radiolabeling (radionuclide-drug conjugates). It contains an activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines and a NOTA chelator for radiometal coordination. Supplied for research use only.
- Activated N-hydroxysuccinimide (NHS) ester for conjugation to primary amines.
- NOTA chelator for stable binding of radiometals.
- Purity ≥97.0%.
- CAS number 1338231-09-6.
- Molecular formula C16H24N4O8; molecular weight 400.38 g/mol.
- Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).