Cycloheptathiophenes
TARGETMOL CHEMICALS INC FORMOTEROL FUMARATE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Formoterol fumarate (Eformoterol Hemifumarate) an effective specific and long-acting (beta)2-adrenoceptor agonist is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma. purity: 99%
Apexbio Technology LLC Rupatadine Fumarate 182349-12-8 10mM (in 1mL Ethanol)
Rupatadine Fumarate (CAS 182349-12-8) is a small molecule antagonist targeting platelet-activating factor receptor (PAFR) and histamine H1 receptor It exhibits binding affinities (K i) of 550 nM at PAFR and 102 nM at the histamine H1 receptor effectively inhibiting signaling mediated by these pathways Through dual antagonism rupatadine fumarate disrupts inflammatory and allergic responses regulated by platelet-activating factor and histamine signaling Currently in Phase 2 clinical development it serves as a valuable pharmacological tool for studying inflammation and allergic conditions
Apexbio Technology LLC Ketotifen Fumarate 34580-14-8 200mg
Ketotifen fumarate is a noncompetitive antagonist of histamine H1 receptors and functions additionally as a mast cell stabilizer It inhibits histamine-mediated allergic responses through preventing histamine receptor activation and limiting mast cell degranulation Its pharmacological activity involves suppression of calcium influx into mast cells thus inhibiting histamine release Ketotifen fumarate is extensively utilized in biomedical research focusing on allergy and asthma pathophysiology to assess mast-cell-mediated mechanisms and histamine signaling pathways In vitro studies report its IC50 values ranging approximately from 0 8 to 2 5 M depending on assay parameters and cell types This compound commonly serves as a pharmacological tool when investigating allergic inflammation asthma and histamine-dependent cellular events
Apexbio Technology LLC GR 89696 fumarate 126766-32-3 10mg
GR 89696 fumarate (CAS 126766-32-3) is a selective agonist of the 2-opioid receptor By specifically activating 2 subtypes this small molecule modulates neural signaling pathways implicated in sensory processing particularly pain and pruritus Experimental studies have demonstrated that GR 89696 fumarate induces physiological effects in the nervous system through 2-opioid receptor activation This compound has been widely utilized as a pharmacological tool in the investigation of neurocutaneous disorders and the underlying mechanisms of opioid receptor-mediated modulation of somatosensory functions
Cayman Chemical DImethyl fumarate 250g
A lipophilic electrophile that has profound effects on oxidative and immunological pathways; activates the transcription factor Nrf2, resulting in heme oxygenase-1 expression and increased glutathione levels; suppresses the expression of pro-inflammatory cytokines and inhibits angiogenesis
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 10mM (in 1mL DMSO)
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Apexbio Technology LLC Quetiapine Fumarate 111974-72-2 10mM (in 1mL DMSO)
Quetiapine Fumarate (CAS 111974-72-2) is a small-molecule atypical antipsychotic with antagonistic activity at dopamine (D1 D2) serotonin (5-HT1A 5-HT2) and adrenergic ( 1 2) receptors In vitro it exhibits affinity for multiple neurotransmitter receptors with dopamine-2 binding characteristics similar to clozapine Preclinical in vivo studies demonstrate antipsychotic effects minimal extrapyramidal side effects and a lower propensity for sustained prolactin elevation Quetiapine has been shown to modulate neurotrophin expression and restore hippocampal neurogenesis following chronic stress in animal models supporting its value in neuropsychiatric and neuropharmacological research
Sigma Aldrich Fine Chemicals Biosciences Ketotifen fumarate salt1G
Ketotifen fumarate salt is an antihistamine drug.
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 5mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders