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Organic bicyclic compounds that consist of a seven-membered ring fused with a thiophene ring; thiophenes are a five-membered ring with four carbon atoms and one sulfur atom.
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi 8.1). Purity 99.5%
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Bedaquiline fumarate is an analytical standard and a diarylquinoline antibiotic that targets ATP synthase, effective for treating *Mycobacterium tuberculosis* infections. This product is intended for research and analytical applications.
Effective for treating *Mycobacterium tuberculosis* infections.
Inhibits growth of TDR *M. tuberculosis* strains.
Shows activity against *Mycobacterium avium*.
Active against *Mycobacterium abscessus* subspecies *abscessus* and *massiliense*.
Possesses moderate in vitro activity against NTM species.
Demonstrates excellent in vitro activity against multidrug resistant *M. tuberculosis*.
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Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
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Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
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Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
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GR 89696 fumarate (CAS 126766-32-3) is a selective agonist of the 2-opioid receptor By specifically activating 2 subtypes this small molecule modulates neural signaling pathways implicated in sensory processing particularly pain and pruritus Experimental studies have demonstrated that GR 89696 fumarate induces physiological effects in the nervous system through 2-opioid receptor activation This compound has been widely utilized as a pharmacological tool in the investigation of neurocutaneous disorders and the underlying mechanisms of opioid receptor-mediated modulation of somatosensory functions
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Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2 2 M1]
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Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2 2 M1]
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Monomethyl fumarate-d3 is the deuterium-labeled analogue of monomethyl fumarate, supplied as an isotopically labeled tracer and internal standard for analytical and pharmacokinetic studies. It is intended for research use in quantitative workflows where precise isotope labeling improves detection and quantitation.
Isotopically labeled internal standard for NMR, GC-MS, and LC-MS.
Useful as a tracer in pharmacokinetic and metabolic profiling.
High analytical purity (≈99.0%).
Provided in small research quantities suitable for analytical assays.
Molecular formula C5H3D3O4; CAS 1616345-41-5.
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Crozbaciclib fumarate is the fumarate salt of crozbaciclib, a small-molecule cyclin-dependent kinase inhibitor selective for CDK4 and CDK6, provided for laboratory research. It exhibits low-nanomolar biochemical potency (CDK4 IC50 ≈ 3 nM; CDK6 IC50 ≈ 1 nM) and demonstrates antiproliferative activity in cellular assays.
Fumarate salt form for improved chemical stability.
Potent inhibition of CDK4 and CDK6 (low-nanomolar IC50s).
High chemical purity (reported 99.4%).
Supplied in small milligram quantities for research use.
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Monomethyl fumarate-d2 is the deuterium-labeled analogue of monomethyl fumarate, supplied as a solid research reagent for use in analytical, pharmacological, and metabolic studies. It serves as an internal standard and tracer in mass spectrometry and mechanistic experiments, and represents the active metabolite of dimethyl fumarate (DMF).
Deuterium labeled for isotope-tracing and mass spectrometry applications.
High purity suitable for analytical reference and research use.
Solid form for stable storage and handling.
Useful as a tracer in metabolic and pharmacokinetic studies.
CAS 253122-44-0 corresponds to the d2 isotopologue.
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