Cycloheptathiophenes
Medchemexpress LLC 3aH-indole-3a-carboxylic acid, biphenyl-4-ylmethyl derivative, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 25 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive fumarate hydratase inhibitor (Ki = 4.5 μM) that exhibits nutrient-dependent cytotoxicity. Supplied as a white to off-white solid intended for research use, it is suitable for cell-based and biochemical studies of fumarate hydratase activity.
- Cell-permeable inhibitor effective in cell-based assays.
- Competitive inhibition with Ki = 4.5 μM for target engagement.
- High purity (98.7%) suitable for research applications.
- Soluble in DMSO and water with warming and sonication.
- Available in small solid quantities and solution formats for flexibility.
![Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215663.png-250.jpg)
Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM). Supplied as the sodium salt as a white to off-white solid, it is intended for biochemical and cell-based research, including studies of metabolic regulation and nutrient-dependent cytotoxicity.
- Cell-permeable competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Sodium salt form for improved solubility in aqueous and polar solvents.
- High purity (98.7%) appropriate for research use.
- Soluble in DMSO (10.66 mg/mL) and water (6.25 mg/mL) with warming and sonication.
- Stable when stored sealed away from moisture; follow solvent storage recommendations.
Medchemexpress LLC 2-butenedioic-2,3-d2 acid, 1-methyl ester, (2E)- | 253122-44-0 | 98.2% | 132.11 | C5H4D2O4 | 5 MG
Monomethyl fumarate-d2 is the deuterium-labeled analogue of monomethyl fumarate, supplied as a solid research reagent for use in analytical, pharmacological, and metabolic studies. It serves as an internal standard and tracer in mass spectrometry and mechanistic experiments, and represents the active metabolite of dimethyl fumarate (DMF).
- Deuterium labeled for isotope-tracing and mass spectrometry applications.
- High purity suitable for analytical reference and research use.
- Solid form for stable storage and handling.
- Useful as a tracer in metabolic and pharmacokinetic studies.
- CAS 253122-44-0 corresponds to the d2 isotopologue.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 25 G
Monoethyl fumarate (2-Butenedioic acid (2E)-, 1-ethyl ester) is the monoethyl ester of fumaric acid supplied as a research reagent. It functions as an NRF2 activator and is used in biochemical and pharmacological studies to probe Keap1-Nrf2 signaling and inflammatory responses. Analytical documentation and high-purity material are provided for reproducible experiments.
- High purity suitable for research applications.
- Documented analytical data (COA, SDS, datasheet) available.
- Useful as an NRF2 activator probe in Keap1-Nrf2 pathway studies.
- Applicable to biochemical, pharmacological, and inflammation/immunology research.
- Available in multiple sizes for flexible experimental scaling.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 1 ML
Monoethyl fumarate is the monoethyl ester of fumaric acid used as a research reagent. It acts as an activator of Nrf2 and is employed as a preservative and polymerization agent for macromolecular materials. The compound is available as a ready-to-use 10 mM solution in DMSO or as a bulk solid and is provided with analytical documentation confirming high purity.
Medchemexpress LLC 2-butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 50 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied as a research reagent and reported Nrf2 activator. It is used in biochemical research and as a preservative and polymerization agent for macromolecular materials. The compound is available as a solid and as a 10 mM solution in DMSO for experimental convenience.
- Activates Nrf2 signaling in research assays.
- High reported purity (99.62%).
- Molecular weight 144.13 g/mol and chemical formula C6H8O4.
- Available in multiple pack sizes and solution form.
- Useful as a preservative and polymerization agent for macromolecular materials.
- For research use only; not for clinical use.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g·mol-1 | C6H8O4 | 10 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied for research use. It functions as an activator of the Nrf2 pathway and is used in biochemical research, and as a preservative and polymerization agent for macromolecular materials. The compound is a white to off-white solid with reported high purity and a molecular weight of 144.13 g·mol-1.
- Activates the Nrf2 pathway in biochemical assays.
- Useful as a preservative and polymerization agent for macromolecular materials.
- Supplied as a solid suitable for formulation or dissolution in common solvents.
- High reported purity supports reproducible experimental results.
- Available in multiple package sizes for experimental flexibility.
- Simple molecular structure amenable to analytical characterization.
AdipoGen Hoechst 34580
Chemical. CAS 911004-45-023555-00-2 free base. Formula C27H29N7 . 3HCl. MW 561. Synthetic. The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. Useful vital stain for the flow cytometric recognition of DNA damage and other viability measurements by monitoring the emission spectral shifts of the dyes. Because this fluorescent stain labels DNA, it can also be used to visualize nuclei and mitochondria. Hoechst 34580 can be excited by violet laser at 405 nm, and emit blue/cyan fluorescence light around an emission maximum at ~440 nm. It is cell-permeable and an excellent tool for flow cytometry studies.
AdipoGen Hoechst 34580
Chemical. CAS 911004-45-023555-00-2 free base. Formula C27H29N7 . 3HCl. MW 561. Synthetic. The Hoechst stains are a family of fluorescent stains for labeling DNA in fluorescence microscopy. The blue fluorescent Hoechst dye is a cell permeable nucleic acid stain that has multiple applications, including sensitive detection of DNA in the presence of RNA in agarose gels, automated DNA determination, sensitive determination of cell number and chromosome sorting. Useful vital stain for the flow cytometric recognition of DNA damage and other viability measurements by monitoring the emission spectral shifts of the dyes. Because this fluorescent stain labels DNA, it can also be used to visualize nuclei and mitochondria. Hoechst 34580 can be excited by violet laser at 405 nm, and emit blue/cyan fluorescence light around an emission maximum at ~440 nm. It is cell-permeable and an excellent tool for flow cytometry studies.
Selleck Chemical LLC Vonoprazan Fumarate
Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H /K ATPase with IC50 of 19 nM (pH 6 5) controls gastric acid secretion Phase 3
Apexbio Technology LLC Dimethyl Fumarate 624-49-7 5g
Dimethyl fumarate (CAS 624-49-7) is a small-molecule activator targeting the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway It is designed to promote Nrf2 nuclear translocation and induce transcription of antioxidant response genes thereby modulating oxidative stress response pathways Dimethyl fumarate exerts its biological activity primarily through activation of Nrf2-mediated antioxidant gene expression In cell-based assays dimethyl fumarate demonstrates Nrf2 activation activity with an IC50 value of approximately 5 M Based on these pharmacological properties dimethyl fumarate holds research potential in the study of oxidative stress inflammation and related pathophysiological processes
Apexbio Technology LLC Dimethyl Fumarate 624-49-7 10mM (in 1mL DMSO)
Dimethyl fumarate (CAS 624-49-7) is a small-molecule activator targeting the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway It is designed to promote Nrf2 nuclear translocation and induce transcription of antioxidant response genes thereby modulating oxidative stress response pathways Dimethyl fumarate exerts its biological activity primarily through activation of Nrf2-mediated antioxidant gene expression In cell-based assays dimethyl fumarate demonstrates Nrf2 activation activity with an IC50 value of approximately 5 M Based on these pharmacological properties dimethyl fumarate holds research potential in the study of oxidative stress inflammation and related pathophysiological processes
Selleck Chemical LLC Ketotifen Fumarate S2024-50mg
Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer
Medchemexpress LLC Ro 48-8071 fumarate | 189197-69-1 | MFCD05865242 | 99.1% | 564.44 g/mol | C27H31BrFNO6 | 10 MG
Ro 48-8071 fumarate is a potent oxidosqualene cyclase (OSC) inhibitor used in research to block cholesterol biosynthesis and to probe cholesterol-dependent cellular pathways in vitro and in vivo. It is supplied as the fumarate salt at high purity for biochemical and cell-based studies.
- Potent oxidosqualene cyclase inhibitor (IC50 ≈ 6.5 nM).
- Suitable for cell-based and in vivo research applications.
- High purity appropriate for biochemical assays (≈99.1%).
- Provided as the fumarate salt to aid stability and handling.
- Molecular weight 564.44 g/mol for accurate dosing and calculations.
- Supplied in small research pack sizes for screening and mechanistic studies.
TARGETMOL CHEMICALS INC Dofequidar fumarate 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the inhibition of ABCB1/P-glycoprotein (P-gp) and ABCC1/MDR-associated protein 1. Purity 99.43%
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