Cycloheptathiophenes
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1,4-diethyl ester | 623-91-6 | 98.97% | 172.18 | 50 G
Diethyl fumarate is an analytical standard intended for research and analytical applications. It is a decomposition product of Malathion 9 (a pesticide) and a reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant and can cause non-immunologic contact urticaria. It can also hybridize with Curcumin to exert neuroprotective effects. The compound is of analytical standard grade and is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
- Can exert neuroprotective effects when hybridized with Curcumin
- Reactant in Diels-Alder reaction
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1,4-diethyl ester | 623-91-6 | 99.0% | 172.18 | 10 MM/ML
Diethyl fumarate (Standard) is the analytical standard of Diethyl fumarate. This product is intended for research and analytical applications. It is a decomposition product of Malathion 9 (a pesticide) and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin hybridize to exert neuroprotective effects.
- Serves as an analytical standard and reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Reactant in the Diels-Alder reaction.
- Exerts neuroprotective effects when hybridized with Curcumin.
Medchemexpress LLC 2-butenedioic-2,3-d2 acid, 1-methyl ester, (2E)- | 253122-44-0 | 98.2% | 132.11 | C5H4D2O4 | 5 MG
Monomethyl fumarate-d2 is the deuterium-labeled analogue of monomethyl fumarate, supplied as a solid research reagent for use in analytical, pharmacological, and metabolic studies. It serves as an internal standard and tracer in mass spectrometry and mechanistic experiments, and represents the active metabolite of dimethyl fumarate (DMF).
- Deuterium labeled for isotope-tracing and mass spectrometry applications.
- High purity suitable for analytical reference and research use.
- Solid form for stable storage and handling.
- Useful as a tracer in metabolic and pharmacokinetic studies.
- CAS 253122-44-0 corresponds to the d2 isotopologue.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 1 ML
Monoethyl fumarate is the monoethyl ester of fumaric acid used as a research reagent. It acts as an activator of Nrf2 and is employed as a preservative and polymerization agent for macromolecular materials. The compound is available as a ready-to-use 10 mM solution in DMSO or as a bulk solid and is provided with analytical documentation confirming high purity.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 25 G
Monoethyl fumarate (2-Butenedioic acid (2E)-, 1-ethyl ester) is the monoethyl ester of fumaric acid supplied as a research reagent. It functions as an NRF2 activator and is used in biochemical and pharmacological studies to probe Keap1-Nrf2 signaling and inflammatory responses. Analytical documentation and high-purity material are provided for reproducible experiments.
- High purity suitable for research applications.
- Documented analytical data (COA, SDS, datasheet) available.
- Useful as an NRF2 activator probe in Keap1-Nrf2 pathway studies.
- Applicable to biochemical, pharmacological, and inflammation/immunology research.
- Available in multiple sizes for flexible experimental scaling.
Medchemexpress LLC 2-butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g/mol | C6H8O4 | 50 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied as a research reagent and reported Nrf2 activator. It is used in biochemical research and as a preservative and polymerization agent for macromolecular materials. The compound is available as a solid and as a 10 mM solution in DMSO for experimental convenience.
- Activates Nrf2 signaling in research assays.
- High reported purity (99.62%).
- Molecular weight 144.13 g/mol and chemical formula C6H8O4.
- Available in multiple pack sizes and solution form.
- Useful as a preservative and polymerization agent for macromolecular materials.
- For research use only; not for clinical use.
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1-ethyl ester | 2459-05-4 | MFCD00002699 | 99.6% | 144.13 g·mol-1 | C6H8O4 | 10 G
Monoethyl fumarate is the monoethyl ester of fumaric acid supplied for research use. It functions as an activator of the Nrf2 pathway and is used in biochemical research, and as a preservative and polymerization agent for macromolecular materials. The compound is a white to off-white solid with reported high purity and a molecular weight of 144.13 g·mol-1.
- Activates the Nrf2 pathway in biochemical assays.
- Useful as a preservative and polymerization agent for macromolecular materials.
- Supplied as a solid suitable for formulation or dissolution in common solvents.
- High reported purity supports reproducible experimental results.
- Available in multiple package sizes for experimental flexibility.
- Simple molecular structure amenable to analytical characterization.
![Medchemexpress LLC 2-butenedioic acid (2e)-, 1-[2-(diethylamino)-2-oxoethyl] 4-methyl ester | 1208229-58-6 | 99.8% | 243.26 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-butenedioic acid (2e)-, 1-[2-(diethylamino)-2-oxoethyl] 4-methyl ester | 1208229-58-6 | 99.8% | 243.26 | 1 ML
Tepilamide fumarate is an oral fumaric acid ester that acts as a proagent of Monomethyl fumarate. It is used in the research of moderate to severe chronic plaque psoriasis and can enhance the effectiveness of oncolytic viruses. In vitro studies show that it makes 786-0 cancer cells more susceptible to infection by VSV∆51, leading to increased virus replication, and selectively promotes oncolytic virus infection in cancer cells without affecting healthy tissues.
- Oral fumaric acid ester
- Acts as a proagent of monomethyl fumarate
- Used in research of moderate to severe chronic plaque psoriasis
- Enhances the effectiveness of oncolytic viruses
- Increases susceptibility of cancer cells to viral infection
- Selectively promotes oncolytic virus infection in cancer cells
Medchemexpress LLC 3aH-indole-3a-carboxylic acid, biphenyl-4-ylmethyl derivative, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 25 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive fumarate hydratase inhibitor (Ki = 4.5 μM) that exhibits nutrient-dependent cytotoxicity. Supplied as a white to off-white solid intended for research use, it is suitable for cell-based and biochemical studies of fumarate hydratase activity.
- Cell-permeable inhibitor effective in cell-based assays.
- Competitive inhibition with Ki = 4.5 μM for target engagement.
- High purity (98.7%) suitable for research applications.
- Soluble in DMSO and water with warming and sonication.
- Available in small solid quantities and solution formats for flexibility.
![Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215663.png-250.jpg)
Medchemexpress LLC 3aH-indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-hexahydro-3-substituted, sodium salt | 2070009-45-7 | 98.7% | 440.47 g/mol | C25H25N2NaO4 | 10 MG
Fumarate hydratase-IN-2 sodium salt is a cell-permeable, competitive inhibitor of fumarate hydratase (Ki = 4.5 μM). Supplied as the sodium salt as a white to off-white solid, it is intended for biochemical and cell-based research, including studies of metabolic regulation and nutrient-dependent cytotoxicity.
- Cell-permeable competitive inhibitor of fumarate hydratase (Ki = 4.5 μM).
- Sodium salt form for improved solubility in aqueous and polar solvents.
- High purity (98.7%) appropriate for research use.
- Soluble in DMSO (10.66 mg/mL) and water (6.25 mg/mL) with warming and sonication.
- Stable when stored sealed away from moisture; follow solvent storage recommendations.
Selleck Chemical LLC Vonoprazan Fumarate
Vonoprazan Fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H /K ATPase with IC50 of 19 nM (pH 6 5) controls gastric acid secretion Phase 3
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