Topiramate (Standard) is the analytical standard of Topiramate, intended for research and analytical applications. Topiramate is a broad-spectrum antiepileptic agent and a GluR5 receptor antagonist. Its antiepileptic effects are produced through the enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase. It is believed to block the spread of seizures.
- Broad-spectrum antiepileptic agent
- GluR5 receptor antagonist
- Enhances GABAergic activity
- Inhibits kainate/AMPA receptors
- Inhibits voltage-sensitive sodium and calcium channels
- Increases potassium conductance
- Inhibits carbonic anhydrase
- Intended for research and analytical applications