Imidazopyrimidines
Medchemexpress LLC Theobromine | 83-67-0 | >99.55% | 180.17 | 1 ML
Theobromine is a methylxanthine found in cacao beans that can inhibit adenosine receptor A1 (AR1) signaling. It is intended for research use only.
- Inhibits adenosine receptor A1 (AR1) signaling
- Decreases lipid accumulation at concentrations above 25 μM without affecting cell viability
- Suppresses protein expression of PPARγ, C/EBPα, and adipogenic genes at concentrations above 25 μM
- Lowers body weight and suppresses gains in epididymal and perirenal adipose tissues in vivo
- Reduces mean adipocyte area in vivo
- Leads to lower bacterial counts per fecal weight in vivo
- Increases fecal pH values in vivo
Research Products International Corp Adenine USP 500 G
A nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine triphosphate and the cofactors nicotinamide adenine dicucleotide and flavin adenine dinucleotide, and protein synthesis, as a chemical component of DNA and RNA.
eMolecules 1185995-18-9 | Medchem Express | Pentoxifylline-d5 | 5mg | 761506653 | HY-B0715S2 | 283.343 | C13H18N4O3
Ambeed | 68-Dichloroimidazo[12-a]pyrazine | 100mg | 600849542 | A892303 | 1245645-38-8 | MFCD18072707 | 188.010 | C6H3Cl2N3
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eMolecules Building Block Tool
Apexbio Technology LLC Adenine HCl 2922-28-3 10mM (in 1mL DMSO)
Adenine HCl is a purine derivative functioning as a fundamental building block of nucleic acids It facilitates the biosynthesis of adenosine triphosphate (ATP) nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD) thus participating in cellular energy metabolism and redox reactions Adenine also exhibits affinity and agonistic properties at adenosine receptors modulating physiological processes In in vitro studies adenine demonstrates cytoprotective activity particularly in renal tubular cell injury models and exerts modulatory effects in vivo on lipid metabolism pathways influencing fatty acid synthesis and mitochondrial -oxidation Based on these properties adenine HCl holds research potential in cellular protection and metabolic disease models
Medchemexpress LLC 6-mercaptopurine hydrate | 6112-76-1 | MFCD03854445 | 99.9% | 170.19 g/mol | C5H6N4OS | 5 MG
6-mercaptopurine hydrate is the hydrated form of the purine analogue 6-mercaptopurine, used in research as an inhibitor of purine metabolism and as a reference compound in biochemical and pharmacological assays.
- Hydrated purine analogue; CAS 6112-76-1.
- Molecular formula C5H6N4OS and molecular weight 170.19 g/mol.
- High purity (99.9% by HPLC) suitable for analytical use.
- Solid monohydrate form with consistent batch characterization.
- Commonly used in in vitro and in vivo pharmacology and biochemical assays.
- Supplied in small research pack sizes for laboratory applications.
Apexbio Technology LLC Theobromine 83-67-0 100mg
Theobromine (CAS 83-67-0) is a methylxanthine alkaloid predominantly present in cocoa beans and consequently in chocolate products with concentrations highest in dark chocolate It functions primarily as a non-selective phosphodiesterase inhibitor and adenosine receptor antagonist leading to increased intracellular cyclic AMP levels and mild central nervous system stimulation Theobromine s pharmacological actions include diuretic bronchodilatory and vasodilatory effects Due to these properties it is utilized in research on cardiovascular and respiratory physiology as well as studies on methylxanthine-related cellular signaling pathways and metabolism
Apexbio Technology LLC Theophylline 58-55-9 5g
Theophylline (CAS 58-55-9) is a methylxanthine alkaloid originally isolated from tea leaves It functions primarily as a nonselective phosphodiesterase inhibitor leading to increased intracellular cyclic AMP levels and acts as an adenosine receptor antagonist These mechanisms underlie its bronchodilatory cardiac stimulant and mild diuretic properties Theophylline is soluble in water ethanol chloroform alkali ammonia water and diluted acids In biomedical research it is utilized to study airway smooth muscle relaxation cardiac physiology and signaling pathways involving cyclic nucleotides The compound should be stored in a tightly sealed container in a cool dry environment
Sigma Aldrich Fine Chemicals Biosciences Adenine | 73-24-5 | MFCD00041790 | 1g
Adenine | Purity: ≥99% | Mol Wt: 135.13 | 73-24-5 | MFCD00041790 | 1g
Sigma Aldrich Fine Chemicals Biosciences Adenine|73-24-5 | MFCD00041790 | 5g
Adenine | Purity: 99%MW: 135.13 | 73-24-5 | MFCD00041790 | 5g
TARGETMOL CHEMICALS INC IBMX 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 uM). IBMX enhances the intracellular cAMP level. Purity 99.8%
Selleck Chemical LLC 3-Methylxanthine
3-Methylxanthine (3-MX) a 3-alkylxanthine is an inhibitor of cyclic guanosine monophosphate (GMP) phosphodiesterase (PDE) with IC50 of 920 M on guinea-pig isolated trachealis muscle
Crescent Chemical Co Inc ISOBUTYL-1-METHYLXANTHINE
Isobutyl-1-methylxanthine research grade Inhibitor of cAMP-phosphodiesterase. Soluble in ethanol. Size - 500MG Storage Conditions - +15 °C TO +30 °C Catalog Number - 26445.02 CAS 28822-58-4
Apexbio Technology LLC Caffeine 10mM (in 1mL DMSO)
N2379 is a small molecule modulator developed for biomedical research applications It selectively targets and modulates specific cellular pathways implicated in disease pathogenesis enabling detailed study of molecular mechanisms in cell signaling and regulation N2379 has been employed in in vitro assays to investigate the compound s effect on cellular responses providing valuable insights into pathway modulation and therapeutic target validation Its use facilitates exploration of disease models supporting the identification and characterization of novel biological targets in drug discovery research
![Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 5 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661465.jpg-250.jpg)
Alkali Scientific Adenine [6 Aminopurine] [Vitamin B4] USP, 5 Grams
Adenine (Vitamin B4) is a purine base crucial for nucleic acid metabolism, widely used in biochemical and molecular biology research. This 5g reagent is essential for studies involving DNA, RNA, and cellular replication. Adenine serves as a key building block in nucleotides and is involved in the synthesis of adenine-containing coenzymes like ATP and NAD. In laboratory settings, Adenine is often used in cell culture media and in experiments exploring gene expression, mutagenesis, and metabolic pathways. It is a critical component in the study of nucleotide biosynthesis and is used in various research applications related to genetics and biochemistry.