MF: C13H13ClN2O, MW: 248.71, Synonyms: EX-527, SIRT1 Inhibitor III, SEN0014196, EX527. Solubility: 12.4 mg/mL in DMSO, 25.45 mg/mL in EtOH with ultrasonic, insoluble in H2O. EX 527 (SEN0014196) is a novel, potential, and specific small-molecule inhibitor of SIRT1 catalytic activity to examine the role of SIRT1 in p53 acetylation and cell survival after DNA damage.