Lactams
Selleck Chemical LLC Tazobactam S3077-500mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect
![eMolecules 16084-57-4 | 3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000472055.jpg-250.jpg)
eMolecules 16084-57-4 | 3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148
3-Azabicyclo[3.2.0]heptane hydrochloride | Synthonix | 16084-57-4 | MFCD22573703 | 133.620 | C6H12ClN | 97.000 | Cl.C1CC2CNCC12 | 1g | 532174148
Medchemexpress LLC VH 101 phenol-alkylC4-amine dihydrochloride | 2564467-03-2 | 676.67 | 25 MG
VH 101 phenol-alkylC4-amine dihydrochloride is a von-Hippel-Lindau protein ligand (VHL). It incorporates an E3 ligase ligand and an alkylC4 linker.
- Von-Hippel-Lindau protein ligand (VHL)
- Incorporates an E3 ligase ligand
- Incorporates an alkylC4 linker
- Can be used for PROTAC research (extracted from patent WO2022051326A1)
Medchemexpress LLC Thalidomide-5-O-C11-NH2 hydrochloride | >98.0% | 480.00 | C24H34ClN3O5 | 10 MG
Thalidomide-5-O-C11-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ligase in targeted protein degradation constructs. Supplied as a white to off-white solid, it is intended for research use in PROTAC synthesis and ligand-linker conjugation. Handle under light protection and low-temperature storage to maintain stability.
- Thalidomide-derived cereblon ligand for E3 ligase recruitment.
- High purity (>98.0% HPLC) suitable for synthetic applications.
- White to off-white solid, convenient for handling and weighing.
- Stable under low-temperature, light-protected storage when handled under nitrogen.
- Available in small research quantities for conjugation and PROTAC development.
Sigma Aldrich Fine Chemicals Biosciences (+)-Thalidomide >=98% (HPLC), powder | 2614-06-4 | MFCD00210220 | 10MG
(+)-Thalidomide >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 258.23 | 2614-06-4 | MFCD00210220 | 10MG
![Medchemexpress LLC 7-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}heptanoic acid | 2169266-69-5 | MFCD32063464 | 99.3% | C20H22N2O7 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261970.png-250.jpg)
Medchemexpress LLC 7-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}heptanoic acid | 2169266-69-5 | MFCD32063464 | 99.3% | C20H22N2O7 | 10MG
Thalidomide-O-C6-COOH is a thalidomide-based cereblon (CRBN) E3 ligase ligand-linker conjugate terminating in a six-carbon carboxylic acid. It is used as a building block in PROTAC synthesis and chemical biology research, providing a convenient carboxylic acid handle for linker attachment and efficient recruitment of CRBN.
- Used in PROTAC design to recruit cereblon (CRBN) E3 ligase.
- Thalidomide-based ligand with a six-carbon carboxylic acid linker.
- High purity, 99.3% (reported).
- Soluble ≥100 mg/mL in DMSO.
- Off-white to light yellow solid suitable for synthesis.
- Molecular formula C20H22N2O7; molecular weight 402.40 g·mol⁻1.
- Storage recommendations provided for powder and solutions to maintain stability.
Medchemexpress LLC Thalidomide-4-O-C7-NH2 hydrochloride | 00-00-0 | 99.8% | C20H26ClN3O5 | 10MG
Thalidomide-4-O-C7-NH2 hydrochloride is a thalidomide-derived cereblon (CRBN) ligand-linker conjugate provided as the hydrochloride salt for research use in PROTAC development and E3 ligase recruitment studies. It is supplied as a high-purity, well-characterized reagent suitable for biochemical assays, linker conjugation, and medicinal chemistry workflows.
- High purity (99.8%) suitable for research applications.
- Hydrochloride salt form for consistent handling and storage.
- Characterized molecular formula C20H26ClN3O5 and molecular weight 387.43 g/mol.
- Functions as a cereblon (CRBN) E3 ligase ligand for PROTAC design.
- Available in small, lab-scale quantities for screening and synthesis.
- Datasheet and certificate of analysis available from the supplier.
Medchemexpress LLC Thalidomide-NH-C6-NH2 TFA | 2093386-51-5 | 99.8% | 50 MG
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a Thalidomide-based cereblon ligand
- Uses a linker in PROTAC technology
- Targets Cereblon
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride | 2983037-00-7 | 98.0% | C25H36ClN5O9 | 10MG
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride is a thalidomide-based cereblon (CRBN) ligand-linker conjugate intended as a building block for PROTAC synthesis. The molecule combines a thalidomide-derived CRBN recruiting moiety with an amino-terminated PEG4-C2 spacer to enable straightforward coupling to target ligands. It is supplied as the hydrochloride salt for improved handling and is for research use only.
- High HPLC purity (98.0%).
- Amino-terminated PEG4-C2 linker for facile conjugation.
- Thalidomide-based cereblon ligand for CRBN recruitment.
- Supplied as a solid hydrochloride salt, light yellow to yellow.
- Available in small-scale quantities suitable for medicinal chemistry.
- Store sealed, away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.