Lactams
Medchemexpress LLC Acy-957 | 1609389-52-7 | 99.6% | 429.54 g/mol | C24H23N5OS | 50 MG
ACY-957 is an orally active, selective small-molecule inhibitor of histone deacetylase isoforms HDAC1 and HDAC2, used for research into epigenetic regulation. It shows potent activity against HDAC1 and HDAC2, reduced activity against HDAC3, and no measurable inhibition of several class II HDACs. The compound is supplied as a high-purity solid and is available in solution formats for assay use.
- Potent inhibition of HDAC1 and HDAC2.
- High selectivity over HDAC3 and class II HDACs.
- Suitable for in vitro and in vivo formulation protocols.
- High reported purity for reliable experimental results.
- Provided as a solid and as ready-to-use DMSO solutions.
- Documented storage and stability conditions for sample handling.
![eMolecules Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502451719.PNG-250.jpg)
eMolecules Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2
Pharmablock / tert-butyl N-(9-azabicyclo[3.3.1]nonan-3-yl)carbamate / 25mg / 721772855 / PBTEN0138 / 0.000 / 1208530-70-4 / MFCD13196387 / 240.347 / C13H24N2O2
Medchemexpress LLC Thalidomide-5-O-CH2-COOH | 2467425-53-0 | MFCD34186095 | 95.0% | 332.26 g/mol | C15H12N2O7 | 50 MG
Thalidomide-5-O-CH2-COOH is an E3 ligase ligand-linker conjugate used as a cereblon (CRBN) ligand and an intermediate for the synthesis of PROTAC molecules. Supplied as a solid with supplier-characterized purity, it is intended for research applications in targeted protein degradation.
- Acts as a cereblon ligand for targeted protein degradation research.
- Suitable intermediate for PROTAC synthesis and conjugation chemistry.
- Approximately 95.0% purity, characterized by supplier analytical data.
- Solid form, light yellow to brown appearance for easy handling.
- Good solubility in DMSO for in vitro formulation and assays.
- Stable when stored under recommended conditions for long-term use.
TARGETMOL CHEMICALS INC Tazobactam 1G
Also available in 1 mL, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Tazobactam (YTR-830H) is an antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases. Purity 100%
Medchemexpress LLC Thalidomide-PEG2-C2-NH2 hydrochloride | 2245697-87-2 | 99.9% | 440.88 g·mol⁻1 | C19H25ClN4O6 | 5 MG
Thalidomide-PEG2-C2-NH2 hydrochloride is a thalidomide-based cereblon E3 ligase ligand-linker conjugate provided as the hydrochloride salt for research use. It combines a thalidomide cereblon-binding moiety with a two-unit polyethylene glycol spacer and a C2 amino termination, designed for incorporation into PROTAC constructs and linker chemistry in targeted protein degradation studies.
- Provides a thalidomide-derived cereblon binding motif suitable for E3 ligase recruitment.
- Contains a PEG2 spacer to improve solubility and linker flexibility.
- Terminates in a C2 amino handle for straightforward conjugation chemistry.
- Supplied as the hydrochloride salt for enhanced stability and handling.
- Characterized with reported molecular weight and purity for research applications.
Medchemexpress LLC Thalidomide-nh-c4-nh-boc | 2093388-52-2 | 99.6% | 444.48 g/mol | C22H28N4O6 | 5 MG
Thalidomide-NH-C4-NH-Boc is a thalidomide-derived E3 ligase ligand-linker conjugate developed for PROTAC research. It combines a cereblon-binding thalidomide moiety with a Boc-protected four-carbon linker to facilitate targeted protein degradation studies. For research use only.
- High purity: 99.64% by analytical HPLC.
- Appropriate for PROTAC development as a cereblon ligand-linker conjugate.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Storage: store at 4°C and protect from light; in solvent, -80°C (6 months) or -20°C (1 month).
- Available in small mg quantities suitable for medicinal chemistry applications.
Selleck Chemical LLC Tazobactam S3077-100mg
Tazobactam (Tazobactam acid Tazobactamum) is a -lactamases Inhibitor with antibacterial activity It also inhibits the class D oxacillinase OXA-2 It is used in combination with piperacillin and other -lactam antibiotics to broaden their spectrum and enhance their effect
![eMolecules Pharmablock / tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate / 25mg / 588505928 / PBLJ18135 / 0.000 / 2227205-60-7 / [null] / 212.293 / C11H20N2O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502458980.PNG-250.jpg)
eMolecules Pharmablock / tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate / 25mg / 588505928 / PBLJ18135 / 0.000 / 2227205-60-7 / [null] / 212.293 / C11H20N2O2
Pharmablock / tert-butyl N-(2-azabicyclo[2.2.1]heptan-6-yl)carbamate / 25mg / 588505928 / PBLJ18135 / 0.000 / 2227205-60-7 / [null] / 212.293 / C11H20N2O2
Medchemexpress LLC Thalidomide-5-PEG6-NH2 hydrochloride | 574.02 g/mol | C25H36ClN3O10 | 10 MG
Thalidomide-5-PEG6-NH2 hydrochloride is a thalidomide-derived cereblon ligand designed as a synthetic building block for targeted protein degradation research. The molecule includes a PEG6 linker terminating in a primary amine (hydrochloride salt) that enables conjugation to linkers or target ligands for PROTAC construction. Storage and handling conditions are provided to maintain stability.
Medchemexpress LLC Thalidomide-O-C8-Boc | 2225148-52-5 | MFCD32701934 | 95.1% | C26H34N2O7 | 10MG
Thalidomide-O-C8-Boc is a thalidomide-derived Cereblon (CRBN) ligand intended for use as the E3 ligase-recruiting moiety in PROTAC design. It features an O-linked eight-carbon spacer with a Boc-protected terminus to enable linker attachment. Manufacturer data report molecular formula C26H34N2O7, molecular weight 486.56, and typical purity ~95%.
- Provides an O-linked C8 spacer with a Boc-protected terminus for linker attachment.
- Suitable for recruiting Cereblon (CRBN) as the E3 ligase in degrader strategies.
- Reported purity approximately 95.1%.
- High solubility in DMSO (100 mg/mL); manufacturer lists example in vivo formulations.
- Recommended storage: solid at -20°C under nitrogen; in solution -80°C (6 months) or -20°C (1 month).