Oxazinanes
eMolecules 1-Naphthylacetyl Spermine Trihydrochloride | 1049731-36-3 | MFCD01321052 | 250mg
Toronto Research Chemicals | 1-Naphthylacetyl Spermine Trihydrochloride | 250mg | 483425926 | N377800 | | 1049731-36-3 | MFCD01321052 | 479.920 | C22H37Cl3N4O
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eMolecules Building Block Tool
Selleck Chemical LLC Cefotiam Hexetil Hydrochloride
Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil Cefotiam is a semi-synthetic beta-lactam cephalosporin antibiotic with antibacterial activity
Cayman Chemical Nefazodone hydrochloride
A serotonin, norepinephrine, and dopamine reuptake inhibitor (Kis = 137, 570, 2,380 nM, respectively); an antagonist of 5-HT2A, 5-HT1A, and histamine H1 receptors, as well as α1- and α2-ARs (Kis = 7.1, 52, 30, 5.5, and 84 nM, respectively); reduces immobility time in the tail suspension test in gerbils at 100 mg/kg; toxic to isolated human hepatocytes in a cultured sandwich hepatocyte preparation at 30 µM
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 200 MG
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor, with IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3 respectively. It demonstrates potent efficacy in xenograft models where Akt is activated due to genetic alterations, leading to tumor growth delay, stasis, or regression. This compound is intended for research use only.
- Highly selective and ATP-competitive pan-Akt inhibitor.
- IC50s of 5, 18, and 8 nM for Akt1, Akt2, and Akt3.
- Significant selectivity for Akt1 compared to closely related kinases.
- Effective in xenograft models with Akt activation due to genetic alterations.
- Induces tumor growth delay, stasis, or regression in vivo.
- Enhances tumor regression and stasis when used in combination therapies.
- Increases tumor growth inhibition in ovarian cancer models when combined with other agents.
eMolecules Ambeed / 4-Bromo-2-methyl-2H-123-triazole / 100mg / 525043181 / A136090 / / 16681-67-7 / MFCD23378485 / 161.990 / C3H4BrN3
Ambeed / 4-Bromo-2-methyl-2H-123-triazole / 100mg / 525043181 / A136090 / / 16681-67-7 / MFCD23378485 / 161.990 / C3H4BrN3
Medchemexpress LLC Clobenpropit dihydrobromide | 145231-35-2 | MFCD00467655 | 99.8% | 470.65 g·mol⁻¹ | C14H19Br2ClN4S | 10 MG
Clobenpropit dihydrobromide is the dihydrobromide salt of clobenpropit, a histamine receptor ligand used for laboratory research. It acts as a potent histamine H3 receptor antagonist/inverse agonist and a partial H4 agonist, with reported additional binding to 5-HT3 and α2 adrenoceptors. The compound is supplied as a high-purity solid for receptor pharmacology and binding studies.
- High purity (99.76%).
- Molecular formula C14H19Br2ClN4S; molecular weight 470.65 g·mol⁻¹.
- CAS number 145231-35-2.
- Potent H3 antagonist/inverse agonist (pEC50 ~8.07).
- Suitable for receptor pharmacology and binding assays.
- Available in small research quantities (e.g., 10 MG).
Selleck Chemical LLC Diphenylpyraline hydrochloride
Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline which is an antihistamine used in the treatment of allergic rhinitis hay fever and allergic skin disorders
Selleck Chemical LLC Chloropyramine hydrochloride
Chloropyramine hydrochloride (Halopyramine) is a histamine receptor H1 antagonist and has anti-cholinergic antispasmodic and antiallergic effects
Selleck Chemical LLC Cytarabine hydrochloride
Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA
Selleck Chemical LLC Olodaterol hydrochloride
Olodaterol hydrochloride (BI-1744) is the hydrochloride salt form of Olodaterol which is a long-acting beta2-adrenergic agonist
Apexbio Technology LLC AMTB hydrochloride 1mg
AMTB hydrochloride (CAS 926023-82-7) is a selective antagonist of the TRPM8 ion channel effectively inhibiting TRPM8-mediated activation induced by agonists such as icilin with a reported pIC50 of approximately 6 23 In addition to its primary action AMTB hydrochloride also exhibits non-selective inhibitory effects on voltage-gated sodium channels (NaV) This compound is commonly utilized in biomedical research to investigate the role of TRPM8 channel activity alterations in the pathophysiology of bladder overactivity and bladder pain syndrome
Medchemexpress LLC 9-Dihydro-13-acetylbaccatin III (9-DHAB III) | 142203-65-4 | 99.6% | C33H42O12 | 1 ML
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate used in the preparation of paclitaxel analogs. This compound exhibits antiproliferative activity against mouse P388 cells, as determined by MTT assay.
- Intermediate for paclitaxel analog preparation
- Purity of 99.6%
- White to off-white solid appearance
- Classified as terpenoids and diterpenoids
- Derived from Taxus chinensis plants
- Demonstrates antiproliferative activity against P388 cells
- Powder stable for up to 3 years at -20°C or 2 years at 4°C
- Solution stable for up to 2 years at -80°C or 1 year at -20°C
- Soluble in DMSO at 20 mg/mL
Cayman Chemical FR122047 hydrochloride
A selective COX-1 inhibitor (IC50 = 0.028 µM for the human enzyme); selective for COX-1 over COX-2 (IC50 = 65 µM); inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation in human platelet-rich plasma (IC50 = 180-200 nM); unlike aspirin, it does not induce gastric damage at 100 mg/kg, p.o.; has an anti-inflammatory effect in a rat models of collagen-induced arthritis