Oxazinanes
Medchemexpress LLC 7,8-Dihydro-L-biopterin (Standard) | 6779-87-9 | 239.23 | 1 MG
7,8-Dihydro-L-biopterin (Standard) | 6779-87-9 | 239.23 | 1 MG
Medchemexpress LLC 5-Bromopentanoyl chloride | 4509-90-4 | 98.63% | 199.47 | 10 G
5-Bromopentanoyl chloride is a PROTAC linker used in PROTAC ATR degrader-2 and for the synthesis of PROTACs. It is intended for research use only.
- PROTAC linker
- Suitable for synthesis of PROTACs
- For research use only
Medchemexpress LLC Prexasertib dihydrochloride | 1234015-54-3 | MFCD25977016 | 99.7% | 10 MG
Prexasertib dihydrochloride is a selective, ATP-competitive CHK1 inhibitor used in preclinical research to probe checkpoint signaling, replication stress, and DNA damage-induced apoptosis. It is suitable for biochemical and cellular assays investigating antitumor mechanisms and pathway dependencies.
- High potency against CHK1 (Ki 0.9 nM; IC50 <1 nM).
- Also inhibits CHK2 and RSK1 at low nanomolar concentrations (CHK2 IC50 8 nM; RSK1 IC50 9 nM).
- Available as solid powder and as DMSO solutions for flexible assay formats.
- Reported high purity appropriate for preclinical studies.
- Useful for studies of DNA damage response, replication catastrophe, and apoptosis.
eMolecules 1201905-61-4 | (E)-1-Ethoxyethene-2-boronic acid pinacol ester | Combi-Blocks | MFCD09998813 | 198.070 | C10H19BO3 | 98.000 | CCO\C=C\B1OC(C)(C)C(C)(C)O1 | 5g | 267161125
(E)-1-Ethoxyethene-2-boronic acid pinacol ester | Combi-Blocks | 1201905-61-4 | MFCD09998813 | 198.070 | C10H19BO3 | 98.000 | CCO\C=C\B1OC(C)(C)C(C)(C)O1 | 5g | 267161125
![Medchemexpress LLC Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride (1:2) | 69-44-3 | 99.97% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000411980-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride (1:2) | 69-44-3 | 99.97% | 1 ML
Amodiaquine dihydrochloride is a 4-aminoquinoline antimalarial agent that is orally active. It functions as a potent inhibitor of histamine N-methyltransferase with a Ki of 18.6 nM, and also acts as a Nurr1 agonist, binding specifically to its ligand-binding domain with an EC50 of approximately 20 μM. This compound also demonstrates anti-inflammatory effects and is for research use only.
- Purity: 99.97%
- Molecular weight: 428.78
- Formula: C20H24Cl3N3O
- CAS number: 69-44-3
- Appearance: Solid
- Color: Light yellow to yellow
- Solubility: Greater than or equal to 125 mg/mL in DMSO (requires sonication), greater than or equal to 50 mg/mL in water (requires sonication)
Apexbio Technology LLC SOLIFENACIN-HYDROCHLORIDE
Solifenacin hydrochloride (CAS No 180468-39-7) is a pharmaceutical compound widely used in biomedical research especially in urology and pharmacological studies It originates from a class of antimuscarinic agents specifically targeting the muscarinic acetylcholine receptors (M3 subtype) to inhibit involuntary bladder contractions This mechanism makes it valuable in researching overactive bladder conditions In vitro studies demonstrate its activity in the nanomolar to low micromolar range highlighting its potency Typical applications include cell models such as bladder smooth muscle cells and various animal studies aiding in drug screening and efficacy evaluation Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC NETICONAZOLE-HYDROCHLORIDE
Neticonazole hydrochloride (CAS No 130773-02-3) is a prominent antifungal agent within the imidazole class primarily explored in biomedical research It originates from synthetic compounds designed to inhibit the growth of pathogenic fungi Its mechanism of action involves disrupting ergosterol synthesis a critical component of fungal cell membranes thereby impairing cell membrane integrity and function Commonly neticonazole hydrochloride exhibits in vitro activity in the nanomolar to low micromolar range showcasing potent antifungal effects It is frequently used in various research applications including cell models and animal studies to assess antifungal efficacy and safety profiles Additionally drug screening programs often incorporate this compound to identify potential therapeutic candidates Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC ATRASENTAN-HYDROCHLORIDE-2MG
Atrasentan hydrochloride (CAS No 195733-43-8) is a potent compound used in biomedical research particularly within the field of oncology and nephrology It is an endothelin receptor antagonist primarily targeting the ETA receptors involved in vasoconstriction and cell proliferation pathways This compound exhibits activity in the nanomolar to low micromolar range which makes it suitable for precise in vitro experiments Atrasentan hydrochloride is commonly utilized in a variety of applications including cell model studies animal research and drug screening processes Its role in inhibiting endothelin-1 mediated pathophysiological processes makes it valuable for studying diseases such as cancer and chronic kidney disease Experimental concentrations typically depend on the specific research design allowing for flexibility in diverse experimental setups
Apexbio Technology LLC NETICONAZOLE-HYDROCHLORIDE
Neticonazole hydrochloride (CAS No 130773-02-3) is a prominent antifungal agent within the imidazole class primarily explored in biomedical research It originates from synthetic compounds designed to inhibit the growth of pathogenic fungi Its mechanism of action involves disrupting ergosterol synthesis a critical component of fungal cell membranes thereby impairing cell membrane integrity and function Commonly neticonazole hydrochloride exhibits in vitro activity in the nanomolar to low micromolar range showcasing potent antifungal effects It is frequently used in various research applications including cell models and animal studies to assess antifungal efficacy and safety profiles Additionally drug screening programs often incorporate this compound to identify potential therapeutic candidates Experimental concentrations typically depend on the specific research design
Apexbio Technology LLC Ligustrazine-Hydrochloride
Ligustrazine Hydrochloride (CAS No 76494-51-4) is a compound primarily used in the field of biomedical research particularly within pharmacology and cardiovascular studies Originating from the Chinese herb Chuanxiong this molecule is known for its ability to inhibit platelet aggregation and improve microcirculation via mechanisms targeting pathways such as nitric oxide release and calcium channel modulation In vitro activity is typically observed in the nanomolar to low micromolar range indicating its potency Ligustrazine Hydrochloride often serves as an experimental agent in cell models and animal studies to explore therapeutic potentials and screen drug candidates Its typical applications include investigating the treatment of cardiovascular diseases and ischemic conditions Experimental concentrations typically depend on the specific research design allowing for flexibility in dosing to suit various investigative protocols
Apexbio Technology LLC NETICONAZOLE-HYDROCHLORIDE
Neticonazole hydrochloride (CAS No 130773-02-3) is a prominent antifungal agent within the imidazole class primarily explored in biomedical research It originates from synthetic compounds designed to inhibit the growth of pathogenic fungi Its mechanism of action involves disrupting ergosterol synthesis a critical component of fungal cell membranes thereby impairing cell membrane integrity and function Commonly neticonazole hydrochloride exhibits in vitro activity in the nanomolar to low micromolar range showcasing potent antifungal effects It is frequently used in various research applications including cell models and animal studies to assess antifungal efficacy and safety profiles Additionally drug screening programs often incorporate this compound to identify potential therapeutic candidates Experimental concentrations typically depend on the specific research design
Medchemexpress LLC Ipatasertib dihydrochloride | 1396257-94-5 | C24H34Cl3N5O2 | 500 MG
Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-Akt inhibitor. It exhibits significant selectivity for Akt1 over closely related kinases PKA and p70S6K, inhibiting only a few other kinases at higher concentrations.
- Highly selective and ATP-competitive pan-Akt inhibitor
- Inhibits Akt1, Akt2, and Akt3
- Exhibits high selectivity against PKA and p70S6K
- Inhibits only three other kinases by more than 70% at 1 μM concentration in a panel of 230 protein kinases
Apexbio Technology LLC Orphenadrine-Hydrochloride
Orphenadrine Hydrochloride (CAS No 341-69-5) is a chemical compound studied in the field of pharmacology and neuroscience for its role as a muscle relaxant and anticholinergic agent It originates from the synthesis of antihistamines and works by blocking NMDA receptors and reducing signaling at neural pathways specifically inhibiting muscarinic acetylcholine receptors This dual mechanism helps in the modulation of neuronal activity and muscle relaxation Common in vitro activity is observed in the nanomolar to low micromolar range indicating its potency Orphenadrine Hydrochloride is frequently used in cell models and animal studies to understand its therapeutic potential and neuroprotective effects It s also applied in drug screening to evaluate its efficacy and safety profile Experimental concentrations typically depend on the specific research design ensuring adaptable application in various scientific investigations
Aobchem Methyl 8-bromo-2 3-dihydro-1 4-benzodioxin-5-carboxylate | 95% | CAS 823225-66-7 | C10H9BrO4 | 1g
Methyl 8-bromo-2 3-dihydro-1 4-benzodioxin-5-carboxylate | 95% | CAS 823225-66-7 | C10H9BrO4 | 1g