Oxazinanes
Medchemexpress LLC 13,14-Dihydro-15-keto-PGE2-d9 | 2750534-81-5 | 361.52 | 25 UG
13,14-Dihydro-15-keto-PGE2-d9 is the deuterium labeled 13,14-Dihydro-15-keto-PGE2. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements
- Affects pharmacokinetic and metabolic profiles of drugs
- For research use only
eMolecules METHYL 2-AMINO-4-(MORPHOLINE-4-CARBONYL)BENZOATE | 322764-64-7 | MFCD11501885 | 1g
AstaTech | METHYL 2-AMINO-4-(MORPHOLINE-4-CARBONYL)BENZOATE | 1g | 112531767 | AR2624 | 95.000 | 322764-64-7 | MFCD11501885 | 264.281 | C13H16N2O4
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Cayman Chemical Leelamine hydrochloride
The hydrochloride of leelamine, an inhibitor of pyruvate dehydrogenase kinase.
Selleck Chemical LLC PF-543 hydrochloride
PF-543 hydrochloride a novel sphingosine-competitive inhibitor of SphK1 inhibits SphK1 with IC50 and Ki of 2 0 nM and 3 6 nM exhibits 100-fold selectivity over the SphK2 isoform PF-543 hydrochloride induces apoptosis necrosis and autophagy
Medchemexpress LLC Decloxizine dihydrochloride | 13073-96-6 | 99.7% | C21H30Cl2N2O2 | 500 MG
Decloxizine dihydrochloride acts as a histamine 1 receptor antagonist and is intended for research use only. This compound presents as a white to off-white solid with a high purity of 99.69%.
- Antagonizes histamine 1 receptors
- Solid form
- High purity of 99.69%
- Suitable for various research applications
- Recommended storage at 4°C in sealed conditions, away from moisture
- Solutions can be stored at -80°C for up to 6 months or -20°C for 1 month
Medchemexpress LLC Sapropterin dihydrochloride | 69056-38-8 | 99.8% | C9H17Cl2N5O3 | 1 ML
Sapropterin dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor. It is effective in reducing blood phenylalanine concentrations and can be used in the study of phenylketonuria (PKU). This compound enhances residual phenylalanine hydroxylase activity to increase phenylalanine oxidation and can also aggravate experimental autoimmune encephalomyelitis (EAE). For research use only.
- Orally active phenylalanine hydroxylase (PAH) cofactor
- Reduces blood phenylalanine concentrations
- Used in the study of phenylketonuria (PKU)
- Enhances residual phenylalanine hydroxylase activity
Selleck Chemical LLC Tribenzagan Hydrochloride
Tribenzagan Hydrochloride (Trimethobenzamide) is an orally available antiemetic agent used in the therapy of nausea and vomiting associated with medications and gastrointestinal viral and other illnesses
Selleck Chemical LLC Kevetrin hydrochloride
Kevetrin hydrochloride (Thioureidobutyronitrile) is a water-soluble small molecule and activator of the tumor suppressor protein p53 with potential antineoplastic activity
Selleck Chemical LLC Vardenafil hydrochloride
Vardenafil (BAY38-9456 Levitra Staxyn) hydrochloride is a selective orally active potent inhibitor of phosphodiesterase (PDE) with IC50 of 0 7 nM 11 nM and 180 nM for PDE5 PDE6 and PDE1 respectively
Selleck Chemical LLC RS-102895 Hydrochloride
RS-102895 hydrochloride (HCl) is a potent antagonist of Chemokine (C-C motif) receptor 2 (CCR2) with IC50 of 360 nM and shows no effect on CCR1 RS-102895 hydrochloride also inhibits human 1a and 1d receptors rat brain cortex 5-HT1a receptor in cells with IC50s of 130 nM 320 nM 470 nM respectively
Selleck Chemical LLC PF-543 hydrochloride
PF-543 hydrochloride a novel sphingosine-competitive inhibitor of SphK1 inhibits SphK1 with IC50 and Ki of 2 0 nM and 3 6 nM exhibits 100-fold selectivity over the SphK2 isoform PF-543 hydrochloride induces apoptosis necrosis and autophagy
Medchemexpress LLC Xamoterol hemifumarate | 73210-73-8 | MFCD00661103 | 99.9% | 397.43 g/mol | C20H29N3O9 | 5 MG
Xamoterol hemifumarate is the hemifumarate salt of xamoterol, a selective beta1-adrenergic receptor agonist used as a research reagent for studies of adrenergic signaling and cardiac arrhythmogenesis. It is supplied as a high-purity solid with options for small-scale mg quantities or DMSO solutions for in vitro assays.
- Selective beta1-adrenergic receptor agonist suitable for receptor pharmacology studies.
- High purity (>99.9%) suitable for analytical and biological assays.
- Supplied as a solid, stable for storage and formulation.
- Available in small mg quantities and as DMSO solutions for immediate use.
- Molecular weight 397.43 g/mol; CAS 73210-73-8.
- Useful for studies of cardiac electrophysiology and arrhythmogenesis.
Medchemexpress LLC Inolitazone dihydrochloride | 223132-38-5 | 98.5% | 575.51 | 100 MG
Inolitazone dihydrochloride is a novel high-affinity PPARγ agonist, demonstrating potent anti-proliferative activities both in vitro and in vivo, with an IC50 of 0.8 nM for growth inhibition. Its biological activity is dependent on PPARγ.
- Upregulates the cell cycle kinase inhibitor p21WAF1/CIP1
- Activates PPARγ:RXRα-dependent transcription at 10 nM
- Specifically activates PPARγ, unlike PPARα or PPARδ
- Exhibits a low EC50 of 1 nM for activating PPARγ in DRO cells
- Potently inhibits growth with an IC50 of 0.8 nM
- Shows additive antiproliferative activity when combined with paclitaxel
- Inhibits tumor growth in a dose-responsive manner in vivo, including established DRO and ARO tumors
Medchemexpress LLC Landiolol hydrochloride | 144481-98-1 | MFCD01937430 | >=98.0% | 546.05 g/mol | C25H40ClN3O8 | 1 ML
Landiolol hydrochloride is a highly selective, ultra-short-acting β1-adrenergic receptor antagonist formulated for research use. It is suitable for in vitro pharmacology and biochemical studies, and is offered as both a ready-to-use solution and as solid material for analytical and formulation purposes.
- Highly selective β1-adrenergic receptor antagonist.
- Ultra-short-acting pharmacological profile suitable for acute studies.
- Available as a 10 mM solution in DMSO and as solid forms for flexibility.
- Provided with molecular and analytical characterization data.
- Designed for in vitro receptor pharmacology and biochemical assays.